Chuai, Manli

Dr

  • United Kingdom

  • 690 Citations
  • 15 h-Index
20062020
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Research Output 2006 2020

  • 690 Citations
  • 15 h-Index
  • 47 Article
  • 2 Review article
  • 1 Chapter
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Article
2020
3 Downloads (Pure)
Open Access
File
Primitive Streak
Germ Layers
Chick Embryo
Intercellular Junctions
Epithelial Cells
2018
4 Citations (Scopus)
100 Downloads (Pure)

Atg7-Mediated Autophagy Is Involved in the Neural Crest Cell Generation in Chick Embryo

Wang, G., Chen, E., Liang, C., Liang, J., Gao, L., Chuai, M., Münsterberg, A., Bao, Y., Cao, L. & Yang, X., Apr 2018, In : Molecular Neurobiology. 55, 4, p. 3523-3536 14 p.

Research output: Contribution to journalArticle

Open Access
File
Neural Crest
Autophagy
Chick Embryo
Neural Tube
Transfection
9 Citations (Scopus)
121 Downloads (Pure)

Baicalin administration attenuates hyperglycemia-induced malformation of cardiovascular system

Wang, G., Liang, J., Gao, L-R., Si, Z-P., Zhang, X-T., Liang, G., Yan, Y., Li, K., Cheng, X., Bao, Y., Chuai, M., Chen, L-G., Lu, D-X. & Yang, X., 14 Feb 2018, In : Cell Death and Disease. 9, 2, p. 1-17 17 p., 234.

Research output: Contribution to journalArticle

Open Access
File
Cardiovascular System
Hyperglycemia
Autophagy
Chick Embryo
Embryonic Structures
2 Citations (Scopus)
143 Downloads (Pure)

Gut microbiota-derived endotoxin enhanced the incidence of cardia bifida during cardiogenesis

Zhang, J., Wang, G., Liu, J., Gao, L., Liu, M., Wang, C-J., Chuai, M., Bao, Y., Li, G., Li, R-M., Zhang, Y. & Yang, X., Dec 2018, In : Journal of Cellular Physiology. 233, 12, p. 9271-9283 13 p.

Research output: Contribution to journalArticle

Open Access
File
Cardia
Endotoxins
Lipopolysaccharides
Incidence
Chick Embryo
92 Downloads (Pure)

High salt-induced excess reactive oxygen species production resulted in heart tube malformation during gastrulation

Gao, L. R., Wang, G., Zhang, J., Li, S., Chuai, M., Bao, Y., Hocher, B. & Yang, X., Sep 2018, In : Journal of Cellular Physiology. 233, 9, p. 7120-7133 14 p.

Research output: Contribution to journalArticle

Open Access
File
Gastrulation
Congenital Heart Defects
Reactive Oxygen Species
Salts
Cell Movement
3 Citations (Scopus)
126 Downloads (Pure)

Lipopolysaccharides (LPS) Induced Angiogenesis During Chicken Embryogenesis is Abolished by Combined ETA/ETB Receptor Blockade

Wang, G., Li, P-Z., Zhang, S-Y., Zhong, S., Chu, C., Zeng, S., Yan, Y., Cheng, X., Chuai, M., Hocher, B. & Yang, X., Aug 2018, In : Cellular Physiology and Biochemistry. 48, 5, p. 2084-2090 7 p.

Research output: Contribution to journalArticle

Open Access
File
Embryonic Development
Lipopolysaccharides
Chickens
Endothelins
Endothelin A Receptors
4 Citations (Scopus)
76 Downloads (Pure)

Role of FGF signalling in neural crest cell migration during early chick embryo development

Zhang, X-T., Wang, G., Li, Y., Chuai, M., Lee, K. K. H. & Yang, X., 6 Dec 2018, In : Zygote. 26, 6, p. 457-464 8 p.

Research output: Contribution to journalArticle

Open Access
File
Neural Crest
Chick Embryo
Embryonic Development
Cell Movement
Neural Tube
2017
5 Citations (Scopus)
218 Downloads (Pure)

Alcohol exposure induces chick craniofacial bone defects by negatively affecting cranial neural crest development

Zhang, P., Wang, G., Lin, Z., Wu, Y., Zhang, J., Liu, M., Lee, K. K. H., Chuai, M. & Yang, X., 5 Nov 2017, In : Toxicology Letters. 281, p. 53-64 12 p.

Research output: Contribution to journalArticle

Open Access
File
Neural Crest
Bone
Ethanol
Alcohols
Bone and Bones
9 Citations (Scopus)
186 Downloads (Pure)

BRE modulates granulosa cell death to affect ovarian follicle development and atresia in the mouse

Yeung, C. K., Wang, G., Yao, Y., Liang, J., Tenny Chung, C. Y., Chuai, M., Lee, K. K. H. & Yang, X., 23 Mar 2017, In : Cell Death and Disease. 8, p. 1-11 11 p., e2697.

Research output: Contribution to journalArticle

Open Access
File
Ovarian Follicle
Granulosa Cells
Cell Death
Brain
Follicular Atresia
1 Citation (Scopus)
114 Downloads (Pure)

Ethanol exposure leads to disorder of blood island formation in early chick embryo

Wang, G., Chen, B-Z., Wang, C-J., Zhang, J., Gao, L., Chuai, M., Bao, Y. & Yang, X., Oct 2017, In : Reproductive Toxicology. 73, p. 96-104 9 p.

Research output: Contribution to journalArticle

Open Access
File
Chick Embryo
Blood
Ethanol
Cell Movement
Cell Differentiation
5 Citations (Scopus)
183 Downloads (Pure)

Robo signaling regulates the production of cranial neural crest cells

Li, Y., Zhang, X-T., Wang, X-Y., Wang, G., Chuai, M., Münsterberg, A. & Yang, X., Dec 2017, In : Experimental Cell Research. 361, 1, p. 73-84 12 p.

Research output: Contribution to journalArticle

Open Access
File
Neural Crest
Cadherins
Parietal Bone
Frontal Bone
Neural Tube
4 Citations (Scopus)
45 Downloads (Pure)

Usage of Dexamethasone Increases the Risk of Cranial Neural Crest Dysplasia in the Chick Embryo

Cheng, X., Li, H., Yan, Y., Wang, G., Berman, Z., Chuai, M. & Yang, X., 27 Apr 2017, In : Toxicological Sciences. 158, 1, p. 36-47 12 p.

Research output: Contribution to journalArticle

Open Access
File
Neural Crest
Chick Embryo
Dexamethasone
Embryonic Development
Embryonic Structures
2016
9 Citations (Scopus)

Angiogenesis is repressed by ethanol exposure during chick embryonic development

Wang, G., Zhong, S., Zhang, S., Ma, Z., Chen, J., Lu, W., Cheng, X., Chuai, M., Lee, K. K. H., Lu, D. & Yang, X., May 2016, In : Journal of Applied Toxicology. 36, 5, p. 692-701

Research output: Contribution to journalArticle

7 Citations (Scopus)

Dexamethasone exposure accelerates endochondral ossification of chick embryos via angiogenesis

Cheng, X., Yan, Y., Chen, J. L., Ma, Z. L., Yang, R. H., Wang, G., Chuai, M., Ka Ho Lee, K. & Yang, X., 1 Jan 2016, In : Toxicological Sciences. 149, 1, p. 167-177 11 p.

Research output: Contribution to journalArticle

Chick Embryo
Osteogenesis
Dexamethasone
Bone
Osteoblasts
5 Citations (Scopus)

Ethanol exposure represses osteogenesis in the developing chick embryo

Li, Z-Y., Ma, Z-L., Lu, W-H., Cheng, X., Chen, J-L., Song, X-Y., Chuai, M., Lee, K. K. H. & Yang, X., Jul 2016, In : Reproductive Toxicology. 62, p. 53-61 9 p.

Research output: Contribution to journalArticle

Chick Embryo
Osteogenesis
Bone
Ethanol
Bone and Bones
7 Citations (Scopus)
101 Downloads (Pure)

Excess Imidacloprid Exposure Causes the Heart Tube Malformation of Chick Embryos

Gao, L., Li, S., Zhang, J., Liang, C., Chen, E., Zhang, S., Chuai, M., Bao, Y., Wang, G. & Yang, X., 30 Nov 2016, In : Journal of Agricultural and Food Chemistry. 64, 47, p. 9078-9088 11 p.

Research output: Contribution to journalArticle

Open Access
File
Congenital Heart Defects
imidacloprid
Chick Embryo
embryo (animal)
chicks
9 Citations (Scopus)
227 Downloads (Pure)

Exposing imidacloprid interferes with neurogenesis through impacting on chick neural tube cell survival

Liu, M., Wang, G., Zhang, S-Y., Zhong, S., Qi, G-L., Wang, C-J., Chuai, M., Lee, K. K. H., Lu, D-X. & Yang, X., 21 Jul 2016, In : Toxicological Sciences. 153, 1, p. 137-148 12 p.

Research output: Contribution to journalArticle

Open Access
File
Neural Tube
Neurogenesis
Cell Survival
Cells
Neural Tube Defects
1 Citation (Scopus)
248 Downloads (Pure)

Exposure to excess Phenobarbital negatively influences the osteogenesis of chick embryos

Yan, Y., Cheng, X., Yang, R-H., Li, H., Chen, J-L., Ma, Z-L., Wang, G., Chuai, M. & Yang, X., 30 Sep 2016, In : Frontiers in Pharmacology. 7, 15 p., 349.

Research output: Contribution to journalArticle

Open Access
File
Chick Embryo
Phenobarbital
Osteogenesis
Chondrocytes
Bone and Bones
15 Citations (Scopus)

Imidacloprid exposure suppresses neural crest cells generation during early chick embryo development

Wang, C-J., Wang, G., Wang, X., Liu, M., Chuai, M., Lee, K. K. H., He, X-S., Lu, D-X. & Yang, X., 15 Jun 2016, In : Journal of Agricultural and Food Chemistry. 64, 23, p. 4705-4715 11 p.

Research output: Contribution to journalArticle

neural crest
Neural Crest
imidacloprid
Chick Embryo
Embryonic Development
6 Citations (Scopus)

Investigating the effect of excess caffeine exposure on placental angiogenesis using chicken 'functional' placental blood vessel network

Ma, Z. L., Wang, G., Lu, W. H., Cheng, X., Chuai, M., Lee, K. K. H. & Yang, X., 1 Feb 2016, In : Journal of Applied Toxicology. 36, 2, p. 285-295 11 p.

Research output: Contribution to journalArticle

Blood vessels
Caffeine
Blood Vessels
Chickens
Chorioallantoic Membrane
9 Citations (Scopus)

Liver Fibrosis Can Be Induced by High Salt Intake through Excess Reactive Oxygen Species (ROS) Production

Wang, G., Yeung, C. K., Wong, W. Y., Zhang, N., Wei, Y. F., Zhang, J. L., Yan, Y., Wong, C. Y., Tang, J. J., Chuai, M., Lee, K. K. H., Wang, L. J. & Yang, X., 24 Feb 2016, In : Journal of Agricultural and Food Chemistry. 64, 7, p. 1610-1617 8 p.

Research output: Contribution to journalArticle

liver cirrhosis
Liver Cirrhosis
Liver
reactive oxygen species
Reactive Oxygen Species
10 Citations (Scopus)

Proper autophagy is indispensable for angiogenesis during chick embryo development

Lu, W. H., Shi, Y. X., Ma, Z. L., Wang, G., Liu, L., Chuai, M., Song, X., Münsterberg, A., Cao, L. & Yang, X., 2 Jul 2016, In : Cell Cycle. 15, 13, p. 1742-1754 13 p.

Research output: Contribution to journalArticle

Autophagy
Chick Embryo
Embryonic Development
Chorioallantoic Membrane
Catenins
2015
5 Citations (Scopus)

Autophagy is involved in ethanol-induced cardia bifida during chick cardiogenesis

Li, S., Wang, G., Gao, L. R., Lu, W. H., Wang, X. Y., Chuai, M., Lee, K. K. H., Cao, L. & Yang, X., 15 Oct 2015, In : Cell Cycle. 14, 20, p. 3306-3317 12 p.

Research output: Contribution to journalArticle

Cardia
Autophagy
Ethanol
Sirolimus
Chick Embryo
10 Citations (Scopus)

Autophagy is involved in high glucose-induced heart tube malformation

Wang, G., Huang, W. Q., Cui, S. D., Li, S., Wang, X. Y., Li, Y., Chuai, M., Cao, L., Li, J., Lu, D. & Yang, X., 2015, In : Cell Cycle. 14, 5, p. 772-783 12 p.

Research output: Contribution to journalArticle

Congenital Heart Defects
Autophagy
Glucose
Dextrocardia
Hypertrophy
5 Citations (Scopus)

Changes in the osmolarity of the embryonic microenvironment induce neural tube defects

Jin, Y. M., Wang, G., Zhang, N., Wei, Y., Li, S., Chen, Y., Chuai, M., Lee, H. S. S., Hocher, B. & Yang, X., May 2015, In : Molecular Reproduction and Development. 82, 5, p. 365-376 12 p.

Research output: Contribution to journalArticle

Neural Tube
Neural Tube Defects
Osmolar Concentration
Bone Morphogenetic Protein 4
Congenital, Hereditary, and Neonatal Diseases and Abnormalities
1 Citation (Scopus)

Effects of antitumor drug sorafenib on chick embryo development

Cheng, Y. S., Wang, X-Y., Wang, G., Li, Y., Chen, Y-L., Chuai, M., Lee, K. K. H., Ding, X-Y. & Yang, X., Jul 2015, In : Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology. 298, 7, p. 1271-1281 11 p.

Research output: Contribution to journalArticle

Chick Embryo
tumor
Antineoplastic Agents
Embryonic Development
embryo
18 Citations (Scopus)
106 Downloads (Pure)

High glucose environment inhibits cranial neural crest survival by activating excessive autophagy in the chick embryo

Wang, X. Y., Li, S., Wang, G., Ma, Z. L., Chuai, M., Cao, L. & Yang, X., 16 Dec 2015, In : Scientific Reports. 5, 16 p., 18321.

Research output: Contribution to journalArticle

Open Access
File
Neural Crest
Autophagy
Chick Embryo
Glucose
Parietal Bone
7 Citations (Scopus)

Misexpression of BRE gene in the developing chick neural tube affects neurulation and somitogenesis

Wang, G., Li, Y., Wang, X-Y., Chuai, M., Chan, J. Y-H., Lei, J., Münsterberg, A., Lee, K. K. H. & Yang, X., 1 Mar 2015, In : Molecular Biology of the Cell. 26, 5, p. 978-992 15 p.

Research output: Contribution to journalArticle

Neurulation
Neural Tube
Gene Expression
Brain
Neurogenesis
69 Citations (Scopus)

Myosin-II-mediated cell shape changes and cell intercalation contribute to primitive streak formation

Rozbicki, E., Chuai, M., Karjalainen, A., Song, F., Sang, H. M., Martin, R., Knolker, H-J., MacDonald, M. & Weijer, C. J., Apr 2015, In : Nature Cell Biology. 17, 4, p. 397-408 12 p.

Research output: Contribution to journalArticle

Primitive Streak
Myosin Type II
Cell Shape
Myosin Type I
Myosin Type V
10 Citations (Scopus)

The impact of high-salt exposure on cardiovascular development in the early chick embryo

Wang, G., Zhang, N., Wei, Y-F., Jin, Y-M., Zhang, S-Y., Cheng, X., Ma, Z-L., Zhao, S-Z., Chen, Y-P., Chuai, M., Hocher, B. & Yang, X., 4 Nov 2015, In : Journal of Experimental Biology. 218, 21, p. 3468-3477 10 p.

Research output: Contribution to journalArticle

Chick Embryo
early development
embryo
embryo (animal)
Salts
2014

Adverse effects of high glucose levels on somite and limb development in avian embryos

Chen, Y., Wang, G., Ma, Z., Li, Y., Wang, X., Cheng, X., Chuai, M., Tang, S., Lee, K. K. H. & Yang, X., 2014, In : Food and Chemical Toxicology. 71, September, p. 1-9 9 p.

Research output: Contribution to journalArticle

Somites
limbs (animal)
embryo (animal)
Embryonic Structures
Extremities
21 Citations (Scopus)

Autophagy functions on EMT in gastrulation of avian embryo

Lu, W., Wang, G., Li, Y., Li, S., Song, X., Wang, X., Chuai, M., Lee, K. K. H., Cao, L. & Yang, X., 1 Sep 2014, In : Cell Cycle. 13, 17, p. 2752-2764 13 p.

Research output: Contribution to journalArticle

Gastrulation
Autophagy
Embryonic Structures
Chick Embryo
Endoderm
16 Citations (Scopus)

Biphasic influence of dexamethasone exposure on embryonic vertebrate skeleton development

Cheng, X., Chen, J., Ma, Z., Zhang, Z., Lv, S., Mai, D., Liu, J., Chuai, M., Lee, K. K. H., Wan, C. & Yang, X., 15 Nov 2014, In : Toxicology and Applied Pharmacology. 281, 1, p. 19-29 11 p.

Research output: Contribution to journalArticle

Skeleton
Dexamethasone
Vertebrates
Chondrocytes
Chick Embryo
16 Citations (Scopus)

Dimethyl phenyl piperazine iodide (DMPP) induces glioma regression by inhibiting angiogenesis

He, Y., Li, Y., Wang, X., He, X., Jun, L., Chuai, M., Lee, K. K. H., Wang, J., Wang, L. & Yang, X., 15 Jan 2014, In : Experimental Cell Research. 320, 2, p. 354-364 11 p.

Research output: Contribution to journalArticle

Iodides
Glioma
Chorioallantoic Membrane
Dimethylphenylpiperazinium Iodide
Cholinergic Agonists
7 Citations (Scopus)
101 Downloads (Pure)

Effects of High Salt-Exposure on the Development of Retina and Lens in 5.5-Day Chick Embryo

Chen, Y., Wang, G., Wang, X., Ma, Z., Chen, Y., Chuai, M., von Websky, K., Hocher, B. & Yang, X., Aug 2014, In : Cellular Physiology and Biochemistry. 34, 3, p. 804-817 14 p.

Research output: Contribution to journalArticle

Open Access
File
Chick Embryo
Lenses
Retina
Salts
In Situ Nick-End Labeling
1 Citation (Scopus)

Endoderm contributes to endocardial composition during cardiogenesis

Li, Y., Wang, X., Ma, Z., Chuai, M., Münsterberg, A., Lee, K. K. & Yang, X., Aug 2014, In : Chinese Science Bulletin. 59, 22, p. 2749-2755 7 p.

Research output: Contribution to journalArticle

heart
pharynx
quails
chimerism
cells
15 Citations (Scopus)
92 Downloads (Pure)

Excess caffeine exposure impairs eye development during chick embryogenesis

Ma, Z-L., Wang, G., Cheng, X., Chuai, M., Kurihara, H., Lee, K. K. H. & Yang, X., Jun 2014, In : Journal of Cellular and Molecular Medicine. 18, 6, p. 1134-43 10 p.

Research output: Contribution to journalArticle

Open Access
File
Caffeine
Embryonic Development
Chick Embryo
Microphthalmos
Reactive Oxygen Species
27 Citations (Scopus)

Excess ROS induced by AAPH causes myocardial hypertrophy in the developing chick embryo

Li, Y., Wang, X-Y., Zhang, Z., Cheng, X., Li, X-D., Chuai, M., Lee, K. K. H., Kurihara, H. & Yang, X., Sep 2014, In : International journal of cardiology. 176, 1, p. 62-73 12 p.

Research output: Contribution to journalArticle

Chick Embryo
Hypertrophy
Reactive Oxygen Species
Cardiomegaly
Cardiac Myocytes
2013
13 Citations (Scopus)

High glucose level induces cardiovascular dysplasia during early embryo development

Jin, Y-M., Zhao, S-Z., Zhang, Z-L., Chen, Y., Cheng, X., Chuai, M., Liu, G-S., Lee, K. K. H. & Yang, X., Aug 2013, In : Experimental and Clinical Endocrinology and Diabetes. 121, 8, p. 448-454 7 p.

Research output: Contribution to journalArticle

Embryonic Development
Cardiac Myocytes
Blood Vessels
Glucose
Yolk Sac
10 Citations (Scopus)
105 Downloads (Pure)

PTEN is involved in modulation of vasculogenesis in early chick embryos

Li, Y., Wang, X. Y., Wu, T., Chuai, M., Lee, K. K. H., Wang, L. J. & Yang, X., 15 Jun 2013, In : Open Biology. 2, 6, p. 587-595 9 p.

Research output: Contribution to journalArticle

Open Access
File
Chick Embryo
embryo (animal)
Blood
chicks
Modulation
11 Citations (Scopus)

Slit/Robo1 signaling regulates neural tube development by balancing neuroepithelial cell proliferation and differentiation

Wang, G., Li, Y., Wang, X., Han, Z., Chuai, M., Wang, L., Ho Lee, K. K., Geng, J. & Yang, X., 2013, In : Experimental Cell Research. 319, 8, p. 1083-1093 11 p.

Research output: Contribution to journalArticle

Neuroepithelial Cells
Neural Tube
Cell Differentiation
Cell Proliferation
Neural Crest
7 Citations (Scopus)

The Negative Influence of High-Glucose Ambience on Neurogenesis in Developing Quail Embryos

Chen, Y., Fan, J., Zhang, Z., Wang, G., Cheng, X., Chuai, M., Lee, K. K. H. & Yang, X., 2013, In : PLoS ONE. 8, 6

Research output: Contribution to journalArticle

Quail
neurogenesis
Neurogenesis
quails
embryo (animal)
2012
22 Citations (Scopus)

Collective epithelial and mesenchymal cell migration during gastrulation

Chuai, M., Hughes, D. & Weijer, C. J., 2012, In : Current Genomics. 13, 4, p. 267-277 11 p.

Research output: Contribution to journalArticle

2011
22 Citations (Scopus)

A 'chemotactic dipole' mechanism for large-scale vortex motion during primitive streak formation in the chick embryo

Sandersius, S. A., Chuai, M., Weijer, C. J. & Newman, T. J., Aug 2011, In : Physical Biology. 8, 4, 11 p., 045008.

Research output: Contribution to journalArticle

17 Citations (Scopus)

Correlating cell behavior with tissue topology in embryonic epithelia

Sandersius, S. A., Chuai, M., Weijer, C. J. & Newman, T. J., 29 Apr 2011, In : PLoS ONE. 6, 4, 11 p., e18081.

Research output: Contribution to journalArticle

2009
18 Citations (Scopus)

Who moves whom during primitive streak formation in the chick embryo

Chuai, M. & Weijer, C. J., Apr 2009, In : HFSP Journal. 3, 2, p. 71-76 6 p.

Research output: Contribution to journalArticle

2006
84 Citations (Scopus)

Cell movement during chick primitive streak formation

Chuai, M., Zeng, W., Yang, X., Boychenko, V., Glazier, J. A. & Weijer, C. J., 2006, In : Developmental Biology. 296, 1, p. 137-149 13 p.

Research output: Contribution to journalArticle

Primitive Streak
Cell Movement
Germ Layers
Embryonic Structures
Blastoderm