• United Kingdom

  • 4858 Citations
  • 38 h-Index
19962019
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Research Output 1996 2019

2019

EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis

Elias, M. S., Wright, S. C., Remenyi, J., Abbott, J. C., Bray, S. E., Cole, C., Edwards, S., Gierlinski, M., Glok, M., McGrath, J. A., Nicholson, W. V., Paternoster, L., Prescott, A. R., Have, S. T., Whitfield, P. D., Lamond, A. I. & Brown, S. J., Aug 2019, In : Journal of Allergy and Clinical Immunology. 144, 2, p. 470-481 12 p.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Skin
Genome-Wide Association Study
Keratinocytes
Skin Diseases
30 Downloads (Pure)
Open Access
File
Differential Expression
Eukaryota
RNA
Gene expression
Gene Expression
1 Citation (Scopus)
54 Downloads (Pure)

Live imaging of marked chromosome regions reveals their dynamic resolution and compaction in mitosis

Eykelenboom, J., Gierlinski, M., Yue, Z., Hegarat, N., Pollard, H., Fukagawa, T., Hochegger, H. & Tanaka, T., 6 May 2019, In : Journal of Cell Biology. 218, 5, p. 1531-1552 22 p.

Research output: Contribution to journalArticle

Open Access
File
Mitosis
Chromatids
Chromosomes
Prophase
G2 Phase
69 Downloads (Pure)

Triggering MSR1 promotes JNK-mediated inflammation in IL-4 activated macrophages

Guo, M., Härtlova, A., Gierlinski, M., Prescott, A., Castellvi, J., Hernandez Losa, J., Petersen, S. K., Wenzel, U. A., Dill, B., Emmerich, C. H., Ramon Y Cajal, S., Russell, D. G. & Trost, M., 3 Jun 2019, In : EMBO Journal. 38, 11, p. 1-15 15 p., e100299.

Research output: Contribution to journalArticle

Open Access
File
Scavenger Receptors
Macrophages
Interleukin-4
Inflammation
Chemical activation
2018
34 Downloads (Pure)
File
Kinetochores
Microtubules
Chromosome Segregation
Aurora Kinase B
Spindle Poles
27 Downloads (Pure)

Live-cell imaging of marked chromosome regions reveals dynamics of mitotic chromosome resolution and compaction

Eykelenboom, J. K., Gierlinski, M., Yue, Z., Hegarat, N., Pollard, H., Fukagawa, T., Hochegger, H. & Tanaka, T. U., 17 May 2018, In : BioRxiv. 53 p.

Research output: Contribution to journalArticle

File
Chromatids
Chromosomes
Prophase
Genomic Instability
G2 Phase
4 Citations (Scopus)
41 Downloads (Pure)

Neural differentiation, selection and transcriptomic profiling of human neuromesodermal progenitor-like cells in vitro

Verrier, L., Davidson, L., Gierlinski, M., Dady, A. & Storey, K., 12 Jul 2018, In : Development. 145, 16, 10 p., dev166215.

Research output: Contribution to journalArticle

Open Access
File
Stem Cells
Spinal Cord
Embryonic Structures
Clustered Regularly Interspaced Short Palindromic Repeats
Population
1 Citation (Scopus)
54 Downloads (Pure)
File
Proteome
Breast
Epithelial Cells
Proteins
Oncogenes
170 Downloads (Pure)

Proteus: an R package for downstream analysis of MaxQuant output

Gierlinski, M., Gastaldello, F., Cole, C. & Barton, G., 20 Sep 2018, In : BioRxiv. 10 p.

Research output: Contribution to journalArticle

Open Access
File
Proteus
Peptides
Mass Spectrometry
Proteins
13 Citations (Scopus)
79 Downloads (Pure)

Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib

Miettinen, T. P., Peltier, J., Härtlova, A., Gierliński, M., Jansen, V. M., Trost, M. & Björklund, M., 15 May 2018, In : EMBO Journal. 37, 10, p. 1-19 19 p., e98359.

Research output: Contribution to journalArticle

Open Access
File
Proteome
Hot Temperature
Proteasome Endopeptidase Complex
Chemical activation
Cells
2017
72 Downloads (Pure)

Mechanisms mitigating problems with multiple kinetochores on one microtubule in early mitosis

Yue, Z., Komoto, S., Gierlinski, M., Pasquali, D., Kitamura, E. & Tanaka, T. U., 15 Jul 2017, In : Journal of Cell Science. 130, 14, p. 2266-2276 11 p.

Research output: Contribution to journalArticle

Open Access
File
Kinetochores
Mitosis
Microtubules
Spindle Poles
Chromosome Segregation
6 Citations (Scopus)
69 Downloads (Pure)

Molecular mechanisms facilitating the initial kinetochore encounter with spindle microtubules

Vasileva, V., Gierlinski, M., Yue, Z., O'Reilly, N., Kitamura, E. & Tanaka, T. U., 26 Apr 2017, In : Journal of Cell Biology. 216, 6, p. 1809-1822 14 p.

Research output: Contribution to journalArticle

Open Access
File
Kinetochores
Microtubules
Saccharomycetales
Mitosis
2016
6 Citations (Scopus)
128 Downloads (Pure)
Open Access
File
Cell Division
Chromatin
Genes
Workflow
Eukaryota
Uncertainty
Error Analysis
Confidence interval
Biophysics
Biostatistics
2015
39 Citations (Scopus)

Correlation between the photon index and X-ray luminosity of black hole X-ray binaries and active galactic nuclei: Observations and interpretation

Yang, Q. X., Xie, F. G., Yuan, F., Zdziarski, A. A., Gierliński, M., Ho, L. C. & Yu, Z., 21 Feb 2015, In : Monthly Notices of the Royal Astronomical Society. 447, 2, p. 1692-1704 13 p.

Research output: Contribution to journalArticle

active galactic nuclei
accretion
luminosity
photons
x rays
25 Citations (Scopus)
64 Downloads (Pure)

High-resolution quantitative proteome analysis reveals substantial differences between phagosomes of RAW 264.7 and bone marrow-derived macrophages

Guo, M., Härtlova, A., Dill, B. D., Prescott, A. R., Gierliński, M. & Trost, M., Sep 2015, In : Proteomics. 15, 18, p. 3169-3174 6 p.

Research output: Contribution to journalArticle

Open Access
File
Phagosomes
Macrophages
Proteome
Bone
Phagocytosis
27 Citations (Scopus)

Quantitative proteome analysis of temporally-resolved phagosomes following uptake via key phagocytic receptors

Dill, B., Gierliński, M., Härtlova, A., González Arandilla, A., Guo, M., Clarke, R. G. & Trost, M., 1 May 2015, In : Molecular & Cellular Proteomics. 14, 5, p. 1334 1349 p., 16.

Research output: Contribution to journalArticle

Open Access
Phagosomes
Macrophages
Proteome
Ligands
Bone
27 Citations (Scopus)
91 Downloads (Pure)

Statistical models for RNA-seq data derived from a two-condition 48-replicate experiment

Gierlinski, M., Cole, C., Schofield, P., Schurch, N. J., Sherstnev, A., Singh, V., Wrobel, N., Gharbi, K., Simpson, G., Owen-Hughes, T., Blaxter, M. & Barton, G. J., 15 Nov 2015, In : Bioinformatics. 31, 22, p. 3625-3630 6 p.

Research output: Contribution to journalArticle

Open Access
File
2014
22 Citations (Scopus)
87 Downloads (Pure)

Evaluation of the diagnostic accuracy of prototype rapid tests for human African trypanosomiasis

Sternberg, J. M., Gierlinski, M., Biéler, S., Ferguson, M. A. J. & Ndung'u, J. M., Dec 2014, In : PLoS Neglected Tropical Diseases. 8, 12, p. e3373 8 p.

Research output: Contribution to journalArticle

Open Access
File
African Trypanosomiasis
Antigens
Routine Diagnostic Tests
Equipment and Supplies
Sensitivity and Specificity
2013
72 Citations (Scopus)

Kinetochores coordinate pericentromeric cohesion and early DNA replication by Cdc7-Dbf4 kinase recruitment

Natsume, T., Müller, C. A., Katou, Y., Retkute, R., Gierlinski, M., Araki, H., Blow, J. J., Shirahige, K., Nieduszynski, C. A. & Tanaka, T. U., 6 Jun 2013, In : Molecular Cell. 50, 5, p. 661-674 14 p.

Research output: Contribution to journalArticle

21 Citations (Scopus)

Stochastic association of neighboring replicons creates replication factories in budding yeast

Saner, N., Karschau, J., Natsume, T., Gierlinski, M., Retkute, R., Hawkins, M., Nieduszynski, C. A., Blow, J. J., de Moura, A. P. S. & Tanaka, T. U., 2013, In : Journal of Cell Biology. 202, 7, p. 1001-1012 12 p.

Research output: Contribution to journalArticle

Replicon
Saccharomycetales
Microscopy
DNA-Directed DNA Polymerase
DNA Replication
69 Citations (Scopus)

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

Saunders, S. P., Goh, C. S. M., Brown, S. J., Palmer, C. N. A., Porter, R. M., Cole, C., Campbell, L. E., Gierlinski, M., Barton, G. J., Schneider, G., Balmain, A., Prescott, A. R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y-A., Tavendale, R., Mukhopadhyay, S., Turner, S. W. & 14 others, Madhok, V. B., Sullivan, F. M., Relton, C., Burn, J., Meggitt, S., Smith, C. H., Allen, M. A., Barker, J. N. W. N., Reynolds, N. J., Cordell, H. J., Irvine, A. D., McLean, W. H. I., Sandilands, A. & Fallon, P. G., Nov 2013, In : Journal of Allergy and Clinical Immunology. 132, 5, p. 1121-1129 9 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Skin
Genes
Mutation
Single Nucleotide Polymorphism
2012
193 Citations (Scopus)

A quantitative spatial proteomics analysis of proteome turnover in human cells

Boisvert, F-M., Ahmad, Y., Gierlinski, M., Charrière, F., Lamont, D., Scott, M., Barton, G. & Lamond, A. I., 1 Mar 2012, In : Molecular & Cellular Proteomics. 11, 3, M111.011429.

Research output: Contribution to journalArticle

Spatial Analysis
Proteome
Proteomics
Cells
Proteins
69 Citations (Scopus)

Live imaging of nascent RNA dynamics reveals distinct types of transcriptional pulse regulation

Muramoto, T., Cannon, D., Gierlinski, M., Corrigan, A., Barton, G. J. & Chubb, J. R., 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 19, p. 7350-7355 6 p.

Research output: Contribution to journalArticle

2011
33 Citations (Scopus)

Kinetochore-Dependent Microtubule Rescue Ensures Their Efficient and Sustained Interactions in Early Mitosis

Gandhi, S. R., Gierlinski, M., Mino, A., Tanaka, K., Kitamura, E., Clayton, L. & Tanaka, T. U., 15 Nov 2011, In : Developmental Cell. 21, 5, p. 920-933 14 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Simulated spectral states of active galactic nuclei and observational predictions

Sobolewska, M. A., Siemiginowska, A. & Gierliński, M., 11 May 2011, In : Monthly Notices of the Royal Astronomical Society. 413, 3, p. 2259-2268 10 p.

Research output: Contribution to journalArticle

active galactic nuclei
prediction
predictions
accretion
corona
2010
31 Citations (Scopus)

Compton scattering as the explanation of the peculiar X-ray properties of Cyg X-3

Zdziarski, A. A., Misra, R. & Gierliński, M., 21 Feb 2010, In : Monthly Notices of the Royal Astronomical Society. 402, 2, p. 767-775 9 p.

Research output: Contribution to journalArticle

scattering
power spectra
energy spectra
x rays
energy
149 Citations (Scopus)

High-resolution whole-genome sequencing reveals that specific Chromatin Domains from most human chromosomes associate with nucleoli

van Koningsbruggen, S., Gierlinski, M., Schofield, P., Martin, D., Barton, G. J., Ariyurek, Y., den Dunnen, J. T. & Lamond, A. I., 1 Nov 2010, In : Molecular Biology of the Cell. 21, 21, p. 3735-3748 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

The X-ray Binary analogy to the first AGN QPO

Middleton, M., Done, C. & Gierliński, M., 15 Jul 2010, X-ray Astronomy-2009: Present Status, Multi-Wavelength Approach and Future Perspectives - Proceedings of the International Conference. Comastri, A., Angelini, L. & Cappi, M. (eds.). AIP Publishing, Vol. 1248. p. 325-328 4 p. (AIP Conference Proceedings; vol. 1248).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

power spectra
slopes
continuums
low frequencies
scaling
2009
60 Citations (Scopus)

RE J1034+396: the origin of the soft X-ray excess and quasi-periodic oscillation

Middleton, M., Done, C., Ward, M., Gierliński, M. & Schurch, N., 21 Mar 2009, In : Monthly Notices of the Royal Astronomical Society. 394, 1, p. 250-260 11 p.

Research output: Contribution to journalArticle

oscillation
oscillations
x rays
active galactic nuclei
energy
73 Citations (Scopus)

Reprocessing of X-rays in the outer accretion disc of the black hole binary XTE J1817-330

Gierliński, M., Done, C. & Page, K., 21 Jan 2009, In : Monthly Notices of the Royal Astronomical Society. 392, 3, p. 1106-1114 9 p.

Research output: Contribution to journalArticle

accretion disks
accretion
x rays
scattering
broadband data
24 Citations (Scopus)

The Seyfert AGN RX J0136.9-3510 and the spectral state of super Eddington accretion flows

Jin, C., Done, C., Ward, M., Gierliński, M. & Mullaney, J., Sep 2009, In : Monthly Notices of the Royal Astronomical Society: Letters. 398, 1, p. L16-L20 5 p.

Research output: Contribution to journalLetter

active galactic nuclei
accretion
oscillation
H beta line
x rays
18 Citations (Scopus)

What can we learn about quasars from αOX measurements in Galactic black hole binaries?

Sobolewska, M. A., Gierliński, M. & Siemiginowska, A., 11 Apr 2009, In : Monthly Notices of the Royal Astronomical Society. 394, 3, p. 1640-1648 9 p.

Research output: Contribution to journalArticle

active galactic nuclei
quasars
radio
x rays
outburst
2008
153 Citations (Scopus)

A periodicity of ∼1 hour in X-ray emission from the active galaxy RE J1034+396

Gierliński, M., Middleton, M., Ward, M. & Done, C., 18 Sep 2008, In : Nature. 455, 7211, p. 369-371 3 p.

Research output: Contribution to journalArticle

active galaxies
periodic variations
active galactic nuclei
x rays
oscillations
42 Citations (Scopus)
42 Downloads (Pure)

High-frequency X-ray variability as a mass estimator of stellar and supermassive black holes

Gierliński, M., Nikołajuk, M. & Czerny, B., 11 Jan 2008, In : Monthly Notices of the Royal Astronomical Society. 383, 2, p. 741-749 9 p.

Research output: Contribution to journalArticle

Open Access
File
estimators
x rays
luminosity
active galactic nuclei
power law

The superorbital variability and triple nature of the X-ray source 4U 1820-303

Zdziarski, A. A., Wen, L. & Gierliński, M., 1 Dec 2008, Astrophysics of Compact Objects - International Conference on Astrophysics of Compact Objects. Vol. 968. 1 p. 244. (AIP Conference Proceedings; vol. 968).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

X Ray Timing Explorer
modulation
eccentricity
x rays
light curve
102 Citations (Scopus)
38 Downloads (Pure)

X-ray irradiation in XTE J1817-330 and the inner radius of the truncated disc in the hard state

Gierliński, M., Done, C. & Page, K., 1 Aug 2008, In : Monthly Notices of the Royal Astronomical Society. 388, 2, p. 753-760 8 p.

Research output: Contribution to journalArticle

Open Access
File
irradiation
radii
plasma
x rays
outburst
2007
45 Citations (Scopus)
37 Downloads (Pure)

An absorption origin for the soft excess in Seyfert 1 active galactic nuclei

Middleton, M., Done, C. & Gierliński, M., 17 Oct 2007, In : Monthly Notices of the Royal Astronomical Society. 381, 4, p. 1426-1436 11 p.

Research output: Contribution to journalArticle

Open Access
File
active galactic nuclei
accretion
accretion disks
galaxies
outflow
68 Citations (Scopus)
32 Downloads (Pure)

Analysing the atolls: X-ray spectral transitions of accreting neutron stars

Gladstone, J., Done, C. & Gierliński, M., 11 Jun 2007, In : Monthly Notices of the Royal Astronomical Society. 378, 1, p. 13-22 10 p.

Research output: Contribution to journalArticle

Open Access
File
atolls
neutron stars
accretion
x rays
hysteresis
21 Citations (Scopus)

Dependence of the orbital modulation of X-rays from 4U 1820-303 on the accretion rate

Zdziarski, A. A., Gierliński, M., Wen, L. & Kostrzewa, Z., 21 May 2007, In : Monthly Notices of the Royal Astronomical Society. 377, 3, p. 1017-1023 7 p.

Research output: Contribution to journalArticle

Open Access
accretion
modulation
orbitals
X Ray Timing Explorer
x rays
590 Citations (Scopus)
accretion
modeling
x rays
luminosity
radio
29 Citations (Scopus)

The iron K feature in narrow line Seyfert 1 galaxies: Evidence for a P Cygni profile?

Done, C., Sobolewska, M. A., Gierliński, M. & Schurch, N. J., 1 Jan 2007, In : Monthly Notices of the Royal Astronomical Society: Letters. 374, 1, p. L15-L19 5 p.

Research output: Contribution to journalLetter

Open Access
ionization
galaxies
iron
profiles
K lines
36 Citations (Scopus)

The superorbital variability and triple nature of the X-ray source 4U 1820-303

Zdziarski, A. A., Wen, L. & Gierliński, M., 21 May 2007, In : Monthly Notices of the Royal Astronomical Society. 377, 3, p. 1006-1016 11 p.

Research output: Contribution to journalArticle

Open Access
eccentricity
oscillation
x rays
oscillations
light curve
2006
70 Citations (Scopus)

Black hole spin in GRS 1915+105

Middleton, M., Done, C., Gierliński, M. & Davis, S. W., 11 Dec 2006, In : Monthly Notices of the Royal Astronomical Society. 373, 3, p. 1004-1012 9 p.

Research output: Contribution to journalArticle

Open Access
radiative transfer
accretion
radio
gravity
X Ray Timing Explorer
27 Citations (Scopus)

Consistency of the black hole mass determination in AGN from the reverberation and the X-ray excess variance method

Nikołajuk, M., Czerny, B., Ziółkowski, J. & Gierliński, M., 11 Aug 2006, In : Monthly Notices of the Royal Astronomical Society. 370, 3, p. 1534-1540 7 p.

Research output: Contribution to journalArticle

Open Access
reverberation
x rays
inclination
galaxies
orbits
42 Citations (Scopus)
36 Downloads (Pure)
Open Access
File
active galactic nuclei
opacity
constancy
luminosity
continuums
56 Citations (Scopus)
36 Downloads (Pure)

Truncated disc versus extremely broad iron line in XTE J1650-500

Done, C. & Gierliński, M., 1 Apr 2006, In : Monthly Notices of the Royal Astronomical Society. 367, 2, p. 659-668 10 p.

Research output: Contribution to journalArticle

Open Access
File
iron
accretion
K lines
relativistic effects
accretion disks
45 Citations (Scopus)
42 Downloads (Pure)

X-ray spectral transitions of black holes from RXTE all-sky monitor

Gierliński, M. & Newton, J., 1 Aug 2006, In : Monthly Notices of the Royal Astronomical Society. 370, 2, p. 837-844 8 p.

Research output: Contribution to journalArticle

Open Access
File
X Ray Timing Explorer
sky
monitors
luminosity
outburst
2005

Accretion in strong gravity: From galactic to supermassive black holes

Done, C. & Gierliński, M., 1 Dec 2005, Astrophysics and Space Science: From X-Ray Binaries to Quasars: Black Holes on all Mass Scales. Springer Netherlands, p. 167-175 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

gravitation
accretion disks
templates
scaling
physics
49 Citations (Scopus)

GRS 1915+105: The distance, radiative processes and energy-dependent variability

Zdziarski, A. A., Gierliński, M., Rao, A. R., Vadawale, S. V. & Mikolajewska, J., 1 Jul 2005, In : Monthly Notices of the Royal Astronomical Society. 360, 3, p. 825-838 14 p.

Research output: Contribution to journalArticle

proportional counters
energy
Gamma Ray Observatory
X Ray Timing Explorer
detectors