Osuna-Cabello, Maria

Mrs

Senior Bioanalyst, Drug Discovery Unit

United Kingdom

Source: Scopus
Calculated based on no. of publications stored in Pure and citations from Scopus

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588 Citations
11 h-Index
20 Article

Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity
Thomas, M., De Rycker, M., Wall, R. J., Spinks, D., Epemolu, O., Manthri, S., Norval, S., Osuna-Cabello, M., Patterson, S., Riley, J., Simeons, F. R. C., Stojanovski, L., Thomas, J., Thompson, S., Naylor, C., Fiandor, J. M., Wyatt, P. G., Marco, M., Wyllie, S., Read, K. D. & 2 others, Miles, T. J. & Gilbert, I. H., 10 Sep 2020, In: Journal of Medicinal Chemistry. 63, 17, p. 9523-9539 17 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
25 Downloads (Pure)
Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis
Thomas, M. G., De Rycker, M., Ajakane, M., Crouch, S. D., Campbell, L., Daugan, A., Fra, G., Guerrero, C., Mackenzie, C. J., MacLean, L., Manthri, S., Martin, F., Norval, S., Osuna-Cabello, M., Riley, J., Shishikura, Y., Miguel-Siles, J., Simeons, F. R. C., Stojanovski, L., Thomas, J. & 7 others, Thompson, S., Velasco, R. F., Fiandor, J. M., Wyatt, P. G., Read, K. D., Gilbert, I. H. & Miles, T. J., 21 Oct 2020, In: RSC Medicinal Chemistry. 11, 10, p. 1168-1177 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
23 Downloads (Pure)
Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1)
Bell, M., Foley, D., Naylor, C., Wood, G., Robinson, C., Riley, J., Epemolu, R., Ellis, L., Scullion, S., Shishikura, Y., Osuna-Cabello, M., Ferguson, L., Pinto, E., Fletcher, D., Katz, E., McLean, W., Wyatt, P., Read, K. & Woodland, C., 14 Mar 2019, In: ACS Medicinal Chemistry Letters. 10, 3, p. 341–347 7 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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2 Citations (Scopus)

161 Downloads (Pure)
Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis
Thomas, M. G., De Rycker, M., Ajakane, M., Albrecht, S., Álvarez-Pedraglio, A. I., Boesche, M., Brand, S., Campbell, L., Cantizani-Perez, J., Cleghorn, L. A. T., Copley, R. C. B., Crouch, S. D., Daugan, A., Drewes, G., Ferrer, S., Ghidelli-Disse, S., Gonzalez, S., Gresham, S. L., Hill, A. P., Hindley, S. J. & 32 others, Lowe, R. M., MacKenzie, C. J., MacLean, L., Manthri, S., Martin, F., Miguel-Siles, J., Nguyen, V. L., Norval, S., Osuna-Cabello, M., Woodland, A., Patterson, S., Pena, I., Quesada-Campos, M. T., Reid, I. H., Revill, C., Riley, J., Ruiz-Gomez, J. R., Shishikura, Y., Simeons, F. R. C., Smith, A., Smith, V. C., Spinks, D., Stojanovski, L., Thomas, J., Thompson, S., Underwood, T., Gray, D. W., Fiandor, J. M., Gilbert, I. H., Wyatt, P. G., Read, K. D. & Miles, T. J., 14 Feb 2019, In: Journal of Medicinal Chemistry. 62, 3, p. 1180-1202 23 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
8 Citations (Scopus)

74 Downloads (Pure)
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
Baragaña, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J. A., Pisco, J. P., Peet, C., Dranow, D. M., Robinson, D. A., Jansen, C., Norcross, N. R., Vinayak, S., Anderson, M., Brooks, C. F., Cooper, C. A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T. E. & 57 others, Hallyburton, I., Horst, B. G., Hulverson, M. A., Ferguson, L., Jiménez-Díaz, M. B., Jumani, R. S., Lorimer, D. D., Love, M. S., Maher, S., Matthews, H., McNamara, C. W., Miller, P., O'Neill, S., Ojo, K. K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L. M., Scullion, P., Sharma, A., Shepherd, S. M., Shishikura, Y., Simeons, F. R. C., Stebbins, E. E., Stojanovski, L., Straschil, U., Tamaki, F. K., Tamjar, J., Torrie, L. S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F-J., Mäser, P., Kyle, D. E., Winzeler, E. A., Myler, P. J., Wyatt, P. G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C. D., Gray, D. W., Fairlamb, A. H., Pisliakov, A. V., Walpole, C., Read, K. D., Van Voorhis, W. C. & Gilbert, I. H., 2 Apr 2019, In: Proceedings of the National Academy of Sciences. 116, 14, p. 7015-7020 6 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
24 Citations (Scopus)

304 Downloads (Pure)

Identification and Optimization of a Series of 8-Hydroxy Naphthyridines with Potent In Vitro Antileishmanial Activity: Initial SAR and Assessment of In Vivo Activity

Identification of 6-amino-1H-pyrazolo[3,4-d]pyrimidines with in vivo efficacy against visceral leishmaniasis

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1)

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis