Stavridis, Marios

Dr

20032019
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Research Output 2003 2019

2019

A missense mutation in the catalytic domain of O-GlcNAc transferase links perturbations in protein O-GlcNAcylation to X-linked intellectual disability

Pravata, V. M., Gundogdu, M., Bartual, S. G., Ferenbach, A. T., Stavridis, M., Õunap, K., Pajusalu, S., Žordania, R., Wojcik, M. H. & van Aalten, D. M. F., 7 Nov 2019, In : FEBS Letters.

Research output: Contribution to journalArticle

Missense Mutation
Intellectual Disability
Catalytic Domain
X ray crystallography
Stem cells
65 Downloads (Pure)

Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability

Pravata, V., Muha, V., Gundogdu, M., Ferenbach, A., Kakade, P., Vandadi, V., Wilmes, A. C., Borodkin, V., Joss, S., Stavridis, M. & van Aalten, D., 23 Jul 2019, In : Proceedings of the National Academy of Sciences. 116, 30, p. 14961-14970 10 p.

Research output: Contribution to journalArticle

Open Access
File
Intellectual Disability
Host Factor 1 Protein
Missense Mutation
Proteome
Catalytic Domain
2016
11 Citations (Scopus)
128 Downloads (Pure)

mRNA Cap methylation in pluripotency and differentiation

Grasso, L., Suska, O., Davidson, L., Gonatopoulos-Pournatzis, T., Williamson, R., Wasmus, L., Wiedlich, S., Peggie, M., Stavridis, M. P. & Cowling, V. H., 2 Aug 2016, In : Cell Reports. 16, 5, p. 1352-1365 14 p.

Research output: Contribution to journalArticle

Open Access
File
Methylation
Random access storage
Messenger RNA
Genes
Gene expression
2015
8 Citations (Scopus)
120 Downloads (Pure)

Neural differentiation of mouse embryonic stem cells in serum-free monolayer culture

Wongpaiboonwattana, W. & Stavridis, M. P., 14 May 2015, In : JoVE: Journal of Visualized Experiments. 99, e52823.

Research output: Contribution to journalArticle

Open Access
File
Embryonic Stem Cells
Stem cells
Cell culture
Monolayers
Microscopy
2014
23 Citations (Scopus)
351 Downloads (Pure)

Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ES cell differentiation without affecting naive to primed cell transition

Speakman, C. M., Domke, T. C. E., Wongpaiboonwattana, W., Sanders, K., Mudaliar, M., van Aalten, D. M. F., Barton, G. J. & Stavridis, M. P., Oct 2014, In : Stem Cells. 32, 10, p. 2605-2615

Research output: Contribution to journalArticle

Open Access
File
Embryonic Stem Cells
Embryoid Bodies
Cell Differentiation
Hydrolases
Up-Regulation
2012

Embryonic stem cells: a signalling perspective

Stavridis, M. P., 2012, Mitochondrial DNA, mitochondria, disease and stem cells. St. John, J. (ed.). Humana Press, p. 49-68 (Stem cell biology and regenerative medicine).

Research output: Chapter in Book/Report/Conference proceedingChapter

Embryonic Stem Cells
Induced Pluripotent Stem Cells
Embryonic Development
Signal Transduction
Animal Models
2011
45 Citations (Scopus)

Specific Glycosaminoglycans Modulate Neural Specification of Mouse Embryonic Stem Cells

Pickford, C. E., Holley, R. J., Rushton, G., Stavridis, M. P., Ward, C. M. & Merry, C. L. R., Apr 2011, In : Stem Cells. 29, 4, p. 629-640 12 p.

Research output: Contribution to journalArticle

2010

Investigating the regulatory role of GAGs in early neural differentiation of mouse embryonic stem cells

Johnson, C. E., Holley, R. J., Rushton, G., Stavridis, M. P., Gallagher, J. T., Ward, C. M. & Merry, C. L. R., Dec 2010, In : International Journal of Experimental Pathology. 91, 6, p. A36-A37 2 p.

Research output: Contribution to journalMeeting abstract

82 Citations (Scopus)

Retinoic acid orchestrates fibroblast growth factor signalling to drive embryonic stem cell differentiation

Stavridis, M. P., Collins, B. J. & Storey, K. G., 15 Mar 2010, In : Development. 137, 6, p. 881-890 10 p.

Research output: Contribution to journalArticle

2009

Mechanisms regulating differentiation onset in the embryonic axis and ES cells

Collins, B. J., Olivera-Martinez, I., Stavridis, M. P. & Storey, K. G., Aug 2009, In : Mechanisms of Development. 126, p. S29-S29 1 p.

Research output: Contribution to journalMeeting abstract

2008
124 Citations (Scopus)

Negative-feedback regulation of FGF signalling by DUSP6/MKP-3 is driven by ERK1/2 and mediated by Ets factor binding to a conserved site within the DUSP6/MKP-3 gene promoter

Ekerot, M., Stavridis, M. P., Delavaine, L., Mitchell, M. P., Staples, C., Owens, D. M., Keenan, I. D., Dickinson, R. J., Storey, K. G. & Keyse, S. M., 1 Jun 2008, In : Biochemical Journal. 412, 2, p. 287-298 12 p.

Research output: Contribution to journalArticle

2007
205 Citations (Scopus)

A discrete period of FGF-induced Erk1/2 signalling is required for vertebrate neural specification

Stavridis, M. P., Lunn, J. S., Collins, B. J. & Storey, K. G., 2007, In : Development. 134, 16, p. 2889-94 6 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factors
Chick Embryo
Embryonic Stem Cells
Phosphatidylinositol 3-Kinases
Vertebrates
80 Citations (Scopus)

Essential alterations of heparan sulfate during the differentiation of embryonic stem cells to Sox1-enhanced green fluorescent protein-expressing neural progenitor cells

Johnson, C. E., Crawford, B. E., Stavridis, M., Ten Dam, G., Wat, A. L., Rushton, G., Ward, C. M., Wilson, V., van Kuppevelt, T. H., Esko, J. D., Smith, A., Gallagher, J. T. & Merry, C. L. R., Aug 2007, In : Stem Cells. 25, 8, p. 1913-23 11 p.

Research output: Contribution to journalArticle

Heparitin Sulfate
Embryonic Stem Cells
Stem Cells
Sulfotransferases
enhanced green fluorescent protein
2003
1025 Citations (Scopus)

Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture

Ying, Q-L., Stavridis, M., Griffiths, D., Li, M. & Smith, A., 2003, In : Nature Biotechnology. 21, 2, p. 183-6 4 p.

Research output: Contribution to journalArticle

Embryonic Stem Cells
Stem cells
Flow Cytometry
Pluripotent Stem Cells
Fibroblast Growth Factors
72 Citations (Scopus)

Neural differentiation of mouse embryonic stem cells

Stavridis, M. P. & Smith, A. G., Feb 2003, In : Biochemical Society Transactions. 31, Pt 1, p. 45-49 5 p.

Research output: Contribution to journalReview article

Embryonic Stem Cells
Stem cells
Pluripotent Stem Cells
Neurology
Drug Discovery
184 Citations (Scopus)

Screening for mammalian neural genes via fluorescence-activated cell sorter purification of neural precursors from Sox1-gfp knock-in mice

Aubert, J., Stavridis, M. P., Tweedie, S., O'Reilly, M., Vierlinger, K., Li, M., Ghazal, P., Pratt, T., Mason, J. O., Roy, D. & Smith, A., 2003, In : Proceedings of the National Academy of Sciences of the United States of America. 100 , Suppl. 1, p. 11836-11841 6 p.

Research output: Contribution to journalArticle

Embryonic Structures
Fluorescence
Neuroepithelial Cells
Embryonic Stem Cells
Fetal Development