Keyphrases
Trypanosoma Cruzi (T. cruzi)
100%
Leishmania Infantum
94%
Leishmania Donovani
82%
Chagas Disease
68%
Amastigote
53%
Antileishmanial Activity
53%
Antidepressants
47%
Relative Fitness
47%
Antiparasitic
47%
Escitalopram
47%
Amaryllidaceae
47%
Hippeastrum
47%
5-Nitroimidazoles
47%
Isoquinoline Alkaloids
47%
Fucosyltransferase
47%
In Vitro Assessment
47%
Benzofuran-3(2H)-one
47%
Mechanism of Action
47%
Aryl Aldehydes
47%
Multidrug-resistant
47%
Rapid Assessment
47%
Cross-resistance
47%
Antileishmanial Potential
47%
Multi-target
47%
Bioactivation
47%
Visceral Leishmaniasis
42%
Alkaloids
41%
Cruzain
35%
Axenic Amastigotes
35%
T. Cruzi Epimastigotes
31%
Non-reducing
31%
T. Brucei
31%
Gene Products
31%
Malic Enzyme
31%
Overexpression
31%
Promastigote
29%
L. Major
27%
Leishmania Major
27%
Mode of Action
27%
IC50 Value
24%
Cytotoxicity
23%
Multiple Cell Lines
23%
Nitroreductase
23%
Trypomastigote
23%
4-Nitroimidazole
23%
Antileishmanial Compounds
23%
IC50
23%
Single Mitochondrion
22%
Drug Resistance
17%
Protozoan Parasites
15%
Immunology and Microbiology
Chagas Disease
76%
Trypanosoma Cruzi
70%
Visceral Leishmaniasis
70%
Amastigote
70%
Epimastigote
58%
Leishmania infantum
58%
Gene Product
47%
Amaryllidaceae
47%
Proteasome
47%
Mitochondrion
47%
Upregulation
47%
Leishmania donovani
47%
Antiparasitic Agent
47%
IC50
47%
Cross-Resistance
47%
Cell Cycle
47%
Cruzipain
35%
Cell Line
31%
Cytotoxicity
29%
Protozoa
23%
Enzyme Specificity
23%
Binding Site
23%
Epitope
23%
Cytotoxic Concentration
23%
Immunofluorescence
23%
Trypanosomatid
23%
Leishmania Major
23%
Trypanosoma Brucei
23%
Glycan
23%
Enzyme Activity
23%
Carboxy Terminal Sequence
23%
Cell Membrane
23%
Trypomastigote
23%
Leishmania
23%
Fluorescence Spectroscopy
23%
Incubation Time
23%
Electric Potential
23%
Mitochondrial Membrane Potential
23%
CC50
23%
Drug Resistance
21%
Promastigote
17%
Molecular Docking
17%
DNA Barcoding
15%
Resistant Cell Line
15%
Parasitic Disease
15%
EC50
15%
Illumina Dye Sequencing
15%
Enzyme Inhibition
11%
Pharmacophore
11%
Leishmaniasis
5%
Pharmacology, Toxicology and Pharmaceutical Science
Amastigote
82%
Leishmania infantum
58%
Chagas Disease
52%
IC50
49%
Proteasome
47%
Amaryllidaceae
47%
Isoquinoline Alkaloid
47%
Escitalopram
47%
Antidepressant
47%
Bioactivation
47%
4 Nitroimidazole
47%
Antiparasitic Activity
47%
Cruzipain
35%
Cytotoxicity
31%
Malate Dehydrogenase (Decarboxylating)
31%
Trypanosoma Cruzi
27%
Promastigote
27%
Trypomastigote
23%
Nitroreductase
18%
Leishmania
16%
Chymotrypsin
15%
Proteasome Inhibitor
15%
Enzyme Inhibition
15%
Drug Discovery
15%
Epimastigote
15%
Proteome
15%
Tropical Disease
13%
Lanosterol 14 Alpha-Demethylase
11%
3 Benzofuranone Derivative
9%
2 Methyl 5 Nitroimidazole
9%
Hydroxylamine
9%
Leishmania Major
9%
Monocytic Leukemia
9%
Efficacy Study
6%
Flow Cytometry
6%
Fluorescent Dye
6%
Incubation Time
6%
Adenosine Triphosphate
6%
Drug Repositioning
6%
Visceral Leishmaniasis
6%
Haemanthamine
5%
Lycorine
5%
Interaction Energy
5%
Leishmaniasis
5%
Biological Target
5%
Side Effect
5%
Antiparasitic Agent
5%
Drug Resistance
5%
Natural Product
5%