Projects per year
Personal profile
Biography
Professor Sir Mike Ferguson CBE FRS FRSE FMedSci
Regius Professor of Life Sciences, University of Dundee
Mike obtained a BSc and PhD in Biochemistry from Manchester and London. He was a Postdoctoral Fellow at the Rockefeller University, New York, and the University of Oxford and took up a lectureship at The University of Dundee in 1988. He was promoted to a personal chair in 1994 and appointed the first Regius Professor of Life Sciences in 2013.
His research takes a multidisciplinary approach to understanding the biochemistry of protozoan parasites that cause tropical diseases. He believes in the fundamental importance of working across the Biology / Chemistry interface and is particularly interested in Translational Research. With colleagues, he established the Drug Discovery Unit at the University of Dundee in 2006, which has resulted in several compounds in Phase 1 and 2 clinical trials and the generation of spin-out companies. Mike is also co-Director of the Dundee Proteomics Facility, one of the largest in Europe, that accelerates discovery and translational science, including his own contributions to diagnostic devices for human African trypanosomiasis.
Mike believes that academic research should generate new knowledge and, when appropriate, provide returns for its key stakeholder, the taxpayer. He has contributed to the growth of the Life Sciences sector in Dundee through the provision of research laboratories and technologies and, most recently, has co-led the Growing the Tay Cities BioMedical Cluster component of the Tay Cities Deal - designed to anchor high-growth spin-out companies in this economically depressed region of the UK.
Mike served on the Board of Governors (2012-2021), and as its Deputy Chair (2018-2021), of The Wellcome Trust and as member of the Board of Directors of the Medicines for Malaria Venture (MMV) (2012-2024) and of Wellcome Leap (2019-2022). He currently serves on the Board of Directors of UK Biobank (2022-present), the Medicines Discovery Catapult (2025-present) and chairs the board of PhaSER Bio.
During the pandemic, he has advised government and the DHSC on antibody testing and served on the oversight committee for the National Core Studies.
Education/Academic qualification
Doctor of Philosophy, Cell Surface Glycoconjugates of Trypanosoma cruzi, University of London
31 Oct 1979 → 30 Sept 1982
Award Date: 1 Nov 1982
Bachelor of Science, BSc Biochemistry, University of Manchester
1 Oct 1976 → 30 Jun 1982
Award Date: 1 Jun 1979
External positions
Member Board of Directors, Medicines Discovery Catapult
1 Jan 2025 → …
Chair, Board of Directors
25 Sept 2023 → …
Member Board of Directors UK Biobank
1 Jul 2022 → …
Member of Board of Directors
1 Jan 2020 → …
Member of Board of Directors, Medicines for Malaria Venture (MMV)
1 Nov 2012 → 31 Oct 2024
Deputy Chair of Board of Governors, Wellcome Trust
1 Nov 2012 → 31 Oct 2021
Keywords
- QD Chemistry
- biochemistry
- glycobiology
- Mass Spectrometry
- proteomics
- glycosylphosphatidylinositol
- trypanosoma
- leishmaniasis
- drug discovery
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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SDG 8 Decent Work and Economic Growth
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Collaborations and top research areas from the last five years
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MRC IAA 2021 University of Dundee
Ferguson, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator) & Read, K. (Investigator)
1/04/22 → 31/03/27
Project: Research
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Aref#d: 9354. The establishment of a Post-Genomics and Molecular Interactions Centre at the University of Dundee (Joint Infrastructure Fund)
Cohen, P. (Investigator), Downes, P. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Hunter, B. (Investigator), Lamond, A. (Investigator), Lilley, D. (Investigator), Norman, D. (Investigator), Watts, C. (Investigator) & Williams, J. (Investigator)
Project: Research
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Aref#d: 18913. Development of a diagnostic tool for leishmaniasis (Capacity Building Studentship)
Ferguson, M. (Investigator) & Nikolaev, A. (Investigator)
Project: Research
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SFC Connecting Capability Fund - Innovative Therapeutics for Ageing
Ferguson, M. (Investigator)
Project: Research
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Combining antibiotics to tackle antimicrobial resistance
Hope, W. (Lead / Corresponding author), Nambiar, S., O'Brien, S., Sharland, M., Paterson, D. L., Yin, M., Gilbert, I. H., Ferguson, M., Peacock, S. J., Buchan, I., Reza, N., Dubey, V., Darlow, C. A., Gerada, A., Howard, A. & Pre-X Investigators, Apr 2025, In: Nature Microbiology. 10, 4, p. 813-816 4 p.Research output: Contribution to journal › Comment/debate › peer-review
10 Link opens in a new tab Citations (Scopus) -
Erratum: Author Correction: Combining antibiotics to tackle antimicrobial resistance (Nature microbiology (2025) 10 4 DOI: 10.1038/s41564-025-01969-x.)
Pre-X Investigators, 9 Apr 2025, In: Nature Microbiology. 10, 5, p. 1258 1 p.Research output: Contribution to journal › Comment/debate › peer-review
1 Link opens in a new tab Citation (Scopus) -
Images of Microbiology 2
Goddard, P., Lawson, T., Stanley-Wall, N., Rathie, G. (Designer), Papakyriacou , P. (Contributing member), Wood, A. (Contributing member), Da Silva Pacheco, J. (Contributing member), Garcia Sanchez, M. (Contributing member), Escudero-Martinez, C. (Contributing member), Munro, F. (Contributing member), Mansoor, S. (Contributing member), Escrivani, D. O. (Contributing member), Stevens, S. (Contributing member), Ferguson, M. (Contributing member), Elcombe, C. (Contributing member), De Rycker, M. (Contributing member), Ndeh, D. (Contributing member), Balahmar, A. (Contributing member), Keddy , C. (Contributing member) & Singh, V. (Contributing member) & 20 others, , Apr 2025, 30 p. Dundee : University of Dundee.Research output: Other contribution
Open AccessFile358 Downloads (Pure) -
A proposed pathway from D-glucose to D-arabinose in eukaryotes
Iljazi, E., Nagar, R., Kuettel, S., Lucas, K., Crossman, A., Badet-Denisot, M.-A., Woodard, R. W. & Ferguson, M. A. J. (Lead / Corresponding author), Aug 2024, In: Journal of Biological Chemistry. 300, 8, 11 p., 107500.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)140 Downloads (Pure) -
A SARS-CoV-2 minimum data standard to support national serology reporting
Urwin, E. (Lead / Corresponding author), Martin, J., Sebire, N., Harris, A., Johnston, J., Masood, E., Milligan, G., Mairs, L., Chuter, A., Ferguson, M., Quinlan, P. & Jefferson, E., Nov 2024, In: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 61, 6, p. 418-445 28 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)140 Downloads (Pure)
Datasets
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BindingDB Entry 50044865: Lead optimization of a pyrazole sulfonamide series of Trypanosoma brucei N-myristoyltransferase inhibitors: identification and evaluation of CNS penetrant compounds as potential treatments for stage 2 human African trypanosomiasis.
BindingDB, Brand, S. (Creator), Norcross, N. (Creator), Thompson, S. (Creator), Harrison, J. (Creator), Smith, V. (Creator), Robinson, D. (Creator), Torrie, L. (Creator), McElroy, S. (Creator), Hallyburton, I. (Creator), Norval, S. (Creator), Scullion, P. (Creator), Stojanovski, L. (Creator), Simeons, F. (Creator), van Aalten, D. (Creator), Frearson, J. (Creator), Brenk, R. (Creator), Fairlamb, A. (Creator), Ferguson, M. (Creator), Wyatt, P. (Creator), Gilbert, I. (Creator) & Read, K. (Creator), BindingDB, 13 Mar 2016
DOI: 10.7270/q2zc84g2
Dataset
Prizes
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American Society for Biochemistry and Molecular Biology (ASBMB) Alice and CC Wang Award for Molecular Parasitology
Ferguson, M. (Recipient), 1 Jun 2016
Prize: Prize (including medals and awards)
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C.A. Wright Medal of the British Society for Parasitology
Ferguson, M. (Recipient), 1 Jun 2006
Prize: Prize (including medals and awards)
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Colworth Medal of the Biochemical Society
Ferguson, M. (Recipient), 1 Jun 1991
Prize: Prize (including medals and awards)
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Commander of the Order of the British Empire (CBE)
Ferguson, M. (Recipient), 1 Jun 2008
Prize: National/international honour
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Deputy Chair, Board of Governors, Wellcome Trust
Ferguson, M. (Recipient), 1 Jan 2018
Prize: Appointment
Activities
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Open Targets advisory board
Ferguson, M. (Consultant)
30 Sept 2021 → 1 Oct 2021Activity: Consultancy types › Consultancy
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Saturday Series - Ageing Society
Wallace, L. (Organiser), Ferguson, M. (Presenter), Sixsmith, J. (Presenter), Muqit, M. (Presenter), Kelly, T. (Presenter) & Murray, P. (Organiser)
13 Mar 2021Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Saturday Series - What is the University of Dundee doing about Infectious Diseases?
Wallace, L. (Organiser), Ferguson, M. (Presenter), Cantrell, D. (Chair), Downes, P. (Host) & Murray, P. (Organiser)
14 May 2016Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Discovery Days 2012
Downes, P. (Chair), Urch, J. (Organiser), Ker, J. (Presenter), Roslender, R. (Presenter), Jindal-Snape, D. (Presenter), Parkes, S. (Presenter), Connell, J. (Chair), Rouse, J. (Presenter), Sani, F. (Presenter), Baldwin, J. (Presenter), Whatley, C. (Chair), Dawson, T. (Presenter), Wilkinson, C. (Presenter), Jones, M. (Presenter), Inns, T. (Chair), McGuigan, A. (Presenter), Hector, M. (Presenter), Jones, R. (Presenter), Ferguson, M. (Chair), Bekker, P. (Presenter), Newman, T. (Presenter), Smith, B. (Presenter), Whitehorn, M. (Presenter), Miller, D. (Presenter) & Black, S. (Presenter)
12 Jan 2012 → 13 Jan 2012Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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668th Meeting of the Biochemical Society
Ferguson, M. A. J. (Participant)
8 Apr 1999Activity: Participating in or organising an event types › Participation in conference
Press/Media
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Drug breakthrough in fight against neglected diseases
Wyatt, P., Fairlamb, A. H. & Ferguson, M. A. J.
1/04/10
1 item of Media coverage
Press/Media: Research