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  • 58 Similar Profiles
Parkinson Disease Medicine & Life Sciences
Phosphorylation Chemical Compounds
Ubiquitin Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
Mitochondrial Degradation Medicine & Life Sciences
Mutation Medicine & Life Sciences
Serine Medicine & Life Sciences

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Projects 2011 2023

Research Output 2006 2018

8 Downloads (Pure)

Are PARKIN patients ideal candidates for dopaminergic cell replacement therapies?

Kunath, T., Natalwala, A., Chan, C., Chen, Y., Stecher, B., Taylor, M., Khan, S. & Muqit, M. M. K., 26 Dec 2018, In : European Journal of Neuroscience. 10 p.

Research output: Contribution to journalArticle

Open Access
File
Cell- and Tissue-Based Therapy
Synucleins
Lewy Bodies
Transplants
Mutation
45 Citations (Scopus)
42 Downloads (Pure)

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

McWilliams, T. G., Prescott, A. R., Montava-Garriga, L., Ball, G., Singh, F., Barini, E., Muqit, M. M. K., Brooks, S. P. & Ganley, I. G., 6 Feb 2018, In : Cell Metabolism. 27, 2, p. 439-449.e5 17 p., e5.

Research output: Contribution to journalArticle

Open Access
File
Mitochondrial Degradation
Parkinson Disease
Dopaminergic Neurons
Microglia
Islets of Langerhans
2 Citations (Scopus)
7 Downloads (Pure)

Phosphorylation of Parkin at Serine65 is essential for its activation in vivo

McWilliams, T. G., Barini, E., Pohjolan-Pirhonen, R., Brooks, S. P., Singh, F., Burel, S., Balk, K., Kumar, A., Montava Garriga, L., Prescott, A., Hassoun, S. M., Mouton-Liger, F., Ball, G., Hills, R., Knebel, A., Ulusoy, A., Di Monte, D. A., Tamjar, J., Antico, O., Fears, K. & 11 othersSmith, L., Brambilla, R., Palin, E., Valori, M., Eerola-Rautio, J., Tienari, P., Corti, O., Dunnett, S. B., Ganley, I., Suomalainen, A. & Muqit, M., 7 Nov 2018, In : Open Biology. 8, 11, p. 1-18 18 p., 181108.

Research output: Contribution to journalArticle

Open Access
File
Phosphorylation
serine
Serine
phosphorylation
Chemical activation
6 Citations (Scopus)
15 Downloads (Pure)

The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1

Barini, E., Miccoli, A., Tinarelli, F., Mulholland, K., Kadri, H., Khanim, F., Stojanovski, L., Read, K. D., Burness, K., Blow, J. J., Mehellou, Y. & Muqit, M. M. K., 2 Mar 2018, In : ChemBioChem. 19, 5, p. 425-429 5 p.

Research output: Contribution to journalArticle

Open Access
File
Niclosamide
Anthelmintics
Protein Kinases
Parkinson Disease
Mitochondrial Membrane Potential
13 Citations (Scopus)
25 Downloads (Pure)

Kinetin Riboside and Its ProTides Activate the Parkinson’s Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial Depolarization

Osgerby, L., Lai, Y-C., Thornton, P. J., Amalfitano, J., Le Duff, C. S., Jabeen, I., Kadri, H., Miccoli, A., Tucker, J. H. R., Muqit, M. M. K. & Mehellou, Y., 27 Apr 2017, In : Journal of Medicinal Chemistry. 60, 8, p. 3518-3524 7 p.

Research output: Contribution to journalArticle

Open Access
File
Parkinson Disease
Prodrugs
Nucleosides
Neurodegenerative Diseases
Hydrolysis

Press / Media

University of Dundee researcher awarded £1.9M to combat Parkinson's disease

Miratul Muqit

16/07/1317/07/13

6 items of media coverage

Press/Media: Research

Thesis

Biochemical characterisation of the Parkinson's disease-associated kinase PINK1: Insights from the insect world

Author: Woodroof, H. I., 2014

Supervisor: Muqit, M. (Supervisor), Van Aalten, D. (Supervisor) & Alessi, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Investigation of regulation and downstream signaling pathway of Parkinson’s disease associated kinase, PINK1

Author: Kondapalli, C., 2013

Supervisor: Alessi, D. (Supervisor) & Muqit, M. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Regulation of the Parkin E3 ligase by PINK1-dependent phosphorylation

Author: Kazlauskaite, A., 2015

Supervisor: Muqit, M. (Supervisor) & Alessi, D. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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