Muqit, Miratul — Discovery - the University of Dundee Research Portal

Kunath, T., Natalwala, A., Chan, C., Chen, Y., Stecher, B., Taylor, M., Khan, S. & Muqit, M. M. K., 26 Dec 2018, In : European Journal of Neuroscience. 10 p.

Research output: Contribution to journal › Article

Open Access

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Cell- and Tissue-Based Therapy

Synucleins

Lewy Bodies

Transplants

Mutation

45 Citations (Scopus)

42 Downloads (Pure)

Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

McWilliams, T. G., Prescott, A. R., Montava-Garriga, L., Ball, G., Singh, F., Barini, E., Muqit, M. M. K., Brooks, S. P. & Ganley, I. G., 6 Feb 2018, In : Cell Metabolism. 27, 2, p. 439-449.e5 17 p., e5.

Research output: Contribution to journal › Article

Open Access

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Mitochondrial Degradation

Parkinson Disease

Dopaminergic Neurons

Microglia

Islets of Langerhans

2 Citations (Scopus)

7 Downloads (Pure)

Phosphorylation of Parkin at Serine65 is essential for its activation in vivo

McWilliams, T. G., Barini, E., Pohjolan-Pirhonen, R., Brooks, S. P., Singh, F., Burel, S., Balk, K., Kumar, A., Montava Garriga, L., Prescott, A., Hassoun, S. M., Mouton-Liger, F., Ball, G., Hills, R., Knebel, A., Ulusoy, A., Di Monte, D. A., Tamjar, J., Antico, O., Fears, K. & 11 othersSmith, L., Brambilla, R., Palin, E., Valori, M., Eerola-Rautio, J., Tienari, P., Corti, O., Dunnett, S. B., Ganley, I., Suomalainen, A. & Muqit, M., 7 Nov 2018, In : Open Biology. 8, 11, p. 1-18 18 p., 181108.

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Open Access

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Phosphorylation

serine

Serine

phosphorylation

Chemical activation

6 Citations (Scopus)

15 Downloads (Pure)

The Anthelmintic Drug Niclosamide and Its Analogues Activate the Parkinson's Disease Associated Protein Kinase PINK1

Barini, E., Miccoli, A., Tinarelli, F., Mulholland, K., Kadri, H., Khanim, F., Stojanovski, L., Read, K. D., Burness, K., Blow, J. J., Mehellou, Y. & Muqit, M. M. K., 2 Mar 2018, In : ChemBioChem. 19, 5, p. 425-429 5 p.

Research output: Contribution to journal › Article

Open Access

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Niclosamide

Anthelmintics

Protein Kinases

Parkinson Disease

Mitochondrial Membrane Potential

13 Citations (Scopus)

25 Downloads (Pure)

Kinetin Riboside and Its ProTides Activate the Parkinson’s Disease Associated PTEN-Induced Putative Kinase 1 (PINK1) Independent of Mitochondrial Depolarization

Osgerby, L., Lai, Y-C., Thornton, P. J., Amalfitano, J., Le Duff, C. S., Jabeen, I., Kadri, H., Miccoli, A., Tucker, J. H. R., Muqit, M. M. K. & Mehellou, Y., 27 Apr 2017, In : Journal of Medicinal Chemistry. 60, 8, p. 3518-3524 7 p.

Research output: Contribution to journal › Article

Open Access

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Parkinson Disease

Prodrugs

Nucleosides

Neurodegenerative Diseases

Hydrolysis