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Muqit, Miratul

Professor

  • Professor (Clinical) & Personal Chair of Experimental Neurology (Clinical), MRC PPU
 https://orcid.org/0000-0001-9733-2404
20062023

Research output per year

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Projects

Validation of antibodies to ubiquitin-conjugated proteins for mitophagy readouts

Muqit, M.

11/12/19 → 10/06/21

Project: Research

Antigen and Validation for New pS228 PINK1 and pT257 PINK1 Antibodies at Abcam

Muqit, M.

1/01/19 → 31/12/20

Project: Research

Investigating the Druggability of Undruggable Targets Using the Affinity Directed Protein Missile System (AdPROM) in Neurodegenerative Disorders

Muqit, M. & Sapkota, G.

10/09/18 → 9/09/21

Project: Research

Searching for New Protein Targets of the PINK1 and Parkin Genes in Parkinsons Disease

Muqit, M.

1/04/18 → 31/03/21

Project: Research

Investigation of the Role of PINK1-dependent Phosphorylation of Rab GTPases in Parkinson's Disease (joint with Technical University of Munich)

Muqit, M.

1/08/16 → 30/11/20

Project: Research

Research Output

PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2 mediated phosphorylation at Threonine72

Vieweg, S., Mulholland, K., Brauning, B., Kacharia, N., Lai, Y-C., Toth, R., Singh, P. K., Volpi, I., Sattler, M., Groll, M., Itzen, A. & Muqit, M. M. K., 30 Mar 2020, In : Biochemical Journal.

Research output: Contribution to journal › Article

Open Access

    • Therapeutic approaches to enhance PINK1/Parkin mediated mitophagy for the treatment of Parkinson's disease

    Miller, S. & Muqit, M. M. K., 13 Jul 2019, In : Neuroscience Letters. 705, p. 7-13 7 p.

    Research output: Contribution to journal › Review article

    Open Access
    File
    • 7 Citations (Scopus)
    83 Downloads (Pure)

    Are PARKIN patients ideal candidates for dopaminergic cell replacement therapies?

    Kunath, T., Natalwala, A., Chan, C., Chen, Y., Stecher, B., Taylor, M., Khan, S. & Muqit, M. M. K., 26 Dec 2018, In : European Journal of Neuroscience. 10 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 1 Citation (Scopus)
    131 Downloads (Pure)

    Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand

    McWilliams, T. G., Prescott, A. R., Montava-Garriga, L., Ball, G., Singh, F., Barini, E., Muqit, M. M. K., Brooks, S. P. & Ganley, I. G., 6 Feb 2018, In : Cell Metabolism. 27, 2, p. 439-449.e5 17 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 109 Citations (Scopus)
    166 Downloads (Pure)

    Phosphorylation of Parkin at Serine65 is essential for its activation in vivo

    McWilliams, T. G., Barini, E., Pohjolan-Pirhonen, R., Brooks, S. P., Singh, F., Burel, S., Balk, K., Kumar, A., Montava Garriga, L., Prescott, A., Hassoun, S. M., Mouton-Liger, F., Ball, G., Hills, R., Knebel, A., Ulusoy, A., Di Monte, D. A., Tamjar, J., Antico, O., Fears, K. & 11 others, Smith, L., Brambilla, R., Palin, E., Valori, M., Eerola-Rautio, J., Tienari, P., Corti, O., Dunnett, S. B., Ganley, I., Suomalainen, A. & Muqit, M., 7 Nov 2018, In : Open Biology. 8, 11, p. 1-18 18 p., 181108.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 15 Citations (Scopus)
    114 Downloads (Pure)

    Prizes

    Fellow of the Royal Society of Edinburgh

    Miratul Muqit (Recipient) & Ian Gilbert (Recipient), 2020

    Prize: Election to learned society

    The Brian Cox Prize for Excellence in Public Engagement with Research: Engaged Researcher of the Year

    Miratul Muqit (Recipient) & Daksha Patel (Recipient), 15 Jan 2020

    Prize: Prize (including medals and awards)

    • Activities

    • 1 Public engagement and outreach - public lecture/debate/seminar

    Discovery Days 2020

    Miratul Muqit (Speaker), Kim Dale (Speaker), David Gray (Speaker), Senga Robertson-Albertyn (Speaker)
    9 Jan 2020 → 10 Jan 2020

    Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar

    Press / Media

    University of Dundee researcher awarded £1.9M to combat Parkinson's disease

    Miratul M. K. Muqit

    16/07/13 → 17/07/13

    6 items of Media coverage

    Press/Media: Research

    Thesis

    Advancing understanding of endogenous PINK1-Parkin signalling linked to Parkinson’s disease

    Author: Balk, K. R., 2019

    Supervisor: Muqit, M. (Supervisor) & Alessi, D. (Supervisor)

    Student thesis: Doctoral Thesis › Doctor of Philosophy

    Biochemical characterisation of the Parkinson's disease-associated kinase PINK1: Insights from the insect world

    Author: Woodroof, H. I., 2014

    Supervisor: Muqit, M. (Supervisor), Van Aalten, D. (Supervisor) & Alessi, D. (Supervisor)

    Student thesis: Doctoral Thesis › Doctor of Philosophy

    File

    Investigating the role of PINK1-dependent Rab signalling in Parkinson's disease

    Author: Mulholland, K. E., 2019

    Supervisor: Muqit, M. (Supervisor) & Alessi, D. (Supervisor)

    Student thesis: Doctoral Thesis › Doctor of Philosophy

    Investigating the role of the Nrf2-Keap1 pathway in mitophagy

    Author: Bento-Pereira, C., 2020

    Supervisor: Dinkova-Kostova, A. (Supervisor) & Muqit, M. (Supervisor)

    Student thesis: Master's Thesis › Master of Science

    File

    Investigation of regulation and downstream signaling pathway of Parkinson’s disease associated kinase, PINK1

    Author: Kondapalli, C., 2013

    Supervisor: Alessi, D. (Supervisor) & Muqit, M. (Supervisor)

    Student thesis: Doctoral Thesis › Doctor of Philosophy

    File