Wiechens, Nicola

Dr

  • 594 Citations
  • 7 h-Index
20092019
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Fingerprint Dive into the research topics where Nicola Wiechens is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 24 Similar Profiles
Chromatin Assembly and Disassembly Medicine & Life Sciences
Nucleosomes Medicine & Life Sciences
Adenosine Triphosphatases Medicine & Life Sciences
Chromatin Medicine & Life Sciences
Mi-2 Nucleosome Remodeling and Deacetylase Complex Medicine & Life Sciences
DNA Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
DNA Helicases Medicine & Life Sciences

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Research Output 2009 2019

  • 594 Citations
  • 7 h-Index
  • 9 Article
3 Citations (Scopus)

BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

Farnaby, W., Koegl, M., Roy, M. J., Whitworth, C., Diers, E., Trainor, N., Zollman, D., Steurer, S., Karolyi-Oezguer, J., Riedmueller, C., Gmaschitz, T., Wachter, J., Dank, C., Galant, M., Sharps, B., Rumpel, K., Traxler, E., Gerstberger, T., Schnitzer, R., Petermann, O. & 17 others, Greb, P., Weinstabl, H., Bader, G., Zoephel, A., Weiss-Puxbaum, A., Ehrenhöfer-Wölfer, K., Wöhrle, S., Boehmelt, G., Rinnenthal, J., Arnhof, H., Wiechens, N., Wu, M-Y., Owen-Hughes, T., Ettmayer, P., Pearson, M., McConnell, D. B. & Ciulli, A., Jul 2019, In : Nature Chemical Biology. 15, 7, p. 672-680 9 p.

Research output: Contribution to journalArticle

Proteolysis
Adenosine Triphosphatases
Biophysics
Neoplasms
Chromatin Assembly and Disassembly

Publisher Correction: BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design

Farnaby, W., Koegl, M., Roy, M. J., Whitworth, C., Diers, E., Trainor, N., Zollman, D., Steurer, S., Karolyi-oezguer, J., Riedmueller, C., Gmaschitz, T., Wachter, J., Dank, C., Galant, M., Sharps, B., Rumpel, K., Traxler, E., Gerstberger, T., Schnitzer, R., Petermann, O. & 17 others, Greb, P., Weinstabl, H., Bader, G., Zoephel, A., Weiss-Puxbaum, A., Ehrenhöfer-Wölfer, K., Wöhrle, S., Boehmelt, G., Rinnenthal, J., Arnhof, H., Wiechens, N., Wu, M-Y., Owen-Hughes, T., Ettmayer, P., Pearson, M., Mcconnell, D. B. & Ciulli, A., 2 Jul 2019, In : Nature Chemical Biology. 15, 8, p. 846 1 p.

Research output: Contribution to journalArticle

Chromatin Assembly and Disassembly
Ubiquitin-Protein Ligases
Nucleosomes
DNA Repair
Chromatin
22 Citations (Scopus)
75 Downloads (Pure)

Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes

Sundaramoorthy, R., Hughes, A. L., Singh, V., Wiechens, N., Ryan, D. P., El-Mkami, H., Petoukhov, M., Svergun, D. I., Treutlein, B., Quack, S., Fischer, M., Michaelis, J., Bottcher, B., Norman, D. G. & Owen-Hughes, T., 13 Apr 2017, In : eLife. 6, 28 p., e22510.

Research output: Contribution to journalArticle

Open Access
File
Chromatin Assembly and Disassembly
Nucleosomes
Chromatin
DNA
Enzymes
23 Citations (Scopus)
98 Downloads (Pure)

The chromatin remodelling enzymes SNF2H and SNF2L position nucleosomes adjacent to CTCF and other transcription

Wiechens, N., Singh, V., Gkikopoulos, T., Schofield, P., Rocha, S. & Owen-Hughes, T., 28 Mar 2016, In : PLoS Genetics.

Research output: Contribution to journalArticle

Open Access
File
nucleosomes
Chromatin Assembly and Disassembly
Nucleosomes
chromatin
binding sites
46 Citations (Scopus)

PICH: A DNA Translocase Specially Adapted for Processing Anaphase Bridge DNA

Biebricher, A., Hirano, S., Enzlin, J. H., Wiechens, N., Streicher, W. W., Huttner, D., Wang, L. H. C., Nigg, E. A., Owen-Hughes, T., Liu, Y., Peterman, E., Wuite, G. J. L. & Hickson, I. D., 12 Sep 2013, In : Molecular Cell. 51, 5, p. 691-701 11 p.

Research output: Contribution to journalArticle

DNA Helicases
Anaphase
DNA
Optical Tweezers
Nucleic Acid Denaturation

Activities 2018 2018

  • 1 Public engagement and outreach - festival/exhibition

Science Saturdays: Guardians of the Genome

Rolf Black (Organiser), Christine Millar (Host), Nicola Wiechens (Presenter), Thomas Owen-Hughes (Contributor), Abigail Corsie (Contributor), Matthias Toman (Contributor), Meng-Ying Wu (Contributor), Seraina Blümli (Contributor), Mahamadou-Lamine Niakate (Contributor), Jason Sharpe (Contributor)
1 Dec 2018

Activity: Other activity typesPublic engagement and outreach - festival/exhibition