Keyphrases
2,4-Diaminopyrimidine
50%
Active Compounds
33%
Adenocarcinoma Cells
50%
Anticancer Activity
50%
Anticryptosporidial
50%
Antifungal Activity
50%
Antimalarial Activity
50%
Biological Evaluation
50%
Calf Model
25%
Chagas Disease
50%
Compound Properties
25%
Cryptosporidium
50%
Drug Development
50%
Drug Discovery
50%
Drug Metabolism
50%
Efficacy in Vivo
50%
Esophageal Adenocarcinoma
50%
Evaluation Structure
50%
Gastrointestinal Infection
25%
Guided Synthesis
50%
Humanized Models
50%
IC50
33%
Immunodeficient Mice
25%
Infection Model
25%
Infectious Diseases
50%
Knowledge Gaps
25%
Lack of Understanding
25%
Leading Causes of Death
25%
Lipophilicity
50%
LysR Family
50%
Metabolism
33%
Mouse Infection
41%
Neglected Infectious Diseases
25%
Niclosamide
50%
Niclosamide Derivatives
50%
Nitazoxanide
25%
Plasmodium Falciparum 3D7
33%
Potential Treatments
25%
Protease Inhibitors
50%
Pyridazinone
50%
Quantitative Structure-activity Relationship
50%
Salicylanilide
50%
Structure-activity Relationship Studies
50%
Structure-based Design
50%
Sulfanyl
50%
Triethanolamine
33%
Trypanosoma Cruzi (T. cruzi)
66%
Unmet Medical Need
25%
Urea
50%
Wild Mice
33%
Pharmacology, Toxicology and Pharmaceutical Science
Active Metabolite
16%
Anthelmintic Agent
10%
Antiapoptotic
10%
Anticancer Drug
10%
Antifungal Activity
50%
Antimalarial Activity
50%
Antimalarial Agent
50%
Carbanilamide
16%
Chagas Disease
50%
Cryo-Electron Microscopy
16%
Cryptosporidiosis
12%
Cryptosporidium
50%
Cytochrome P450
16%
Cytotoxicity
33%
Diseases
58%
Drug Development
50%
Drug Discovery
50%
Drug Metabolism
50%
Drug-Drug Interaction
16%
Efficacy Assessment
16%
Efficacy Study
16%
Esophageal Adenocarcinoma
30%
Ethanolamine
20%
Eumycetoma
10%
Gastrointestinal Infection
12%
IC50
20%
Infection
100%
Leishmania
16%
Leishmania donovani
16%
Lipophilicity
50%
Lysine Transfer RNA Ligase
50%
Mouse Model
41%
Mycobacterium Tuberculosis
16%
Niclosamide
50%
Nitazoxanide
12%
Parasitosis
16%
Pharmacokinetics
29%
Plasmodium Falciparum 3D7
33%
Proteasome
50%
Proteasome Inhibitor
50%
Pyrimidine
50%
Pyrimidine Derivative
16%
QSAR Study
50%
Salicylanilide Derivative
30%
Sulfanyl
50%
Table Salt
10%
Tropical Disease
10%
Trypanosoma Cruzi
66%
Visceral Leishmaniasis
16%
Wild Type Mouse
33%
Immunology and Microbiology
Absorption
10%
Chagas Disease
30%
Cryo-Electron Microscopy
10%
Cryptosporidium
50%
Cytochrome P450
25%
Drug Metabolism
50%
Drug-Drug Interaction
25%
Infectious Disease
75%
Leishmania
10%
Leishmania donovani
25%
Metabolite
50%
Mouse Model
75%
Mycobacterium Tuberculosis
25%
Parasitic Disease
10%
Pharmacokinetics
50%
Proteasome
50%
Species Difference
25%
Transfer RNA
50%
Trypanosoma Cruzi
75%
Visceral Leishmaniasis
10%
Wild Type Mouse
50%
