Research Output per year
Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.
- 23 Similar Profiles
Mycobacterium tuberculosis
Medicine & Life Sciences
Pharmaceutical Preparations
Medicine & Life Sciences
Lysosphingolipid Receptors
Medicine & Life Sciences
Structure-Activity Relationship
Medicine & Life Sciences
Modulators
Chemical Compounds
Methionine-tRNA Ligase
Medicine & Life Sciences
Quinazolinones
Medicine & Life Sciences
Indazoles
Medicine & Life Sciences
Network
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Research Output 2014 2019
- 144 Citations
- 5 h-Index
- 14 Article
Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1)
Bell, M., Foley, D., Naylor, C., Wood, G., Robinson, C., Riley, J., Epemolu, R., Ellis, L., Scullion, S., Shishikura, Y., Osuna-Cabello, M., Ferguson, L., Pinto, E., Fletcher, D., Katz, E., McLean, W., Wyatt, P., Read, K. & Woodland, C., 14 Mar 2019, In : ACS Medicinal Chemistry Letters. 10, 3, p. 341–347 7 p.Research output: Contribution to journal › Article
Open Access
File
Lysosphingolipid Receptors
Drug Discovery
Modulators
Skin
Pharmaceutical Preparations
2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization
Murugesan, D., Ray, P. C., Bayliss, T., Prosser, G. A., Harrison, J. R., Green, K., Soares De Melo, C., Feng, T. S., Street, L. J., Chibale, K., Warner, D. F., Mizrahi, V., Epemolu, O., Scullion, P., Ellis, L., Riley, J., Shishikura, Y., Ferguson, L., Osuna-Cabello, M., Read, K. D. & 10 others, 8 Jun 2018, In : ACS Infectious Diseases. 4, 6, p. 954-969 16 p.Research output: Contribution to journal › Article
Open Access
File
Quinazolinones
Structure-Activity Relationship
Mycobacterium tuberculosis
Adenosine Triphosphate
Allosteric Site
2
Citations
(Scopus)
40
Downloads
(Pure)
Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and it's newly identified fluorinated analogue 2F-MT-45 with metabolite confirmation in urine samples from known drug users
McKenzie, C., Sutcliffe, O. B., Read, K., Scullion, S., Epemolu, R., Fletcher, D., Helander, A., Beck, O., Rylski, A., Antonides, L., Riley, J., Smith, S. & Nic Daeid, N., Jul 2018, In : Forensic Toxicology. 36, 2, p. 359-374 16 p.Research output: Contribution to journal › Article
Open Access
File
Metabolites
Drug Users
Metabolism
Opioid Analgesics
Urine
Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1
Bell, M., Foley, D., Naylor, C., Robinson, C., Riley, J., Epemolu, R., Scullion, S., Shishikura, Y., Katz, E., McLean, W., Wyatt, P., Read, K. & Woodland, C., 30 Jul 2018, In : Bioorganic & Medicinal Chemistry Letters. 5 p.Research output: Contribution to journal › Article
Open Access
File
Lysosphingolipid Receptors
Modulators
Esters
Plasma (human)
Butyrylcholinesterase
Group-based optimization of potent and cell-active inhibitors of the von Hippel-Lindau (VHL) E3 ubiquitin ligase: structure-activity relationships leading to the chemical probe (2S,4R)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)
Soares, P., Gadd, M., Frost, J., Galdeano, C., Ellis, L., Epemolu, R., Rocha, S., Read, K. & Ciulli, A., 2018, In : Journal of Medicinal Chemistry. 61, p. 599-618 19 p.Research output: Contribution to journal › Article
Open Access
File
Ubiquitin-Protein Ligases
Structure-Activity Relationship
Proteolysis
Ligands
Tumor Suppressor Proteins