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Epemolu, Ola

Dr

  • 250 Citations
  • 8 h-Index
20142019

Research output per year

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Research Output

  • 250 Citations
  • 8 h-Index
  • 14 Article

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1)

Bell, M., Foley, D., Naylor, C., Wood, G., Robinson, C., Riley, J., Epemolu, R., Ellis, L., Scullion, S., Shishikura, Y., Osuna-Cabello, M., Ferguson, L., Pinto, E., Fletcher, D., Katz, E., McLean, W., Wyatt, P., Read, K. & Woodland, C., 14 Mar 2019, In : ACS Medicinal Chemistry Letters. 10, 3, p. 341–347 7 p.

Research output: Contribution to journal › Article

Open Access
File
    • 2 Citations (Scopus)
    117 Downloads (Pure)

    2-Mercapto-Quinazolinones as Inhibitors of Type II NADH Dehydrogenase and Mycobacterium tuberculosis: Structure-Activity Relationships, Mechanism of Action and Absorption, Distribution, Metabolism, and Excretion Characterization

    Murugesan, D., Ray, P. C., Bayliss, T., Prosser, G. A., Harrison, J. R., Green, K., Soares De Melo, C., Feng, T. S., Street, L. J., Chibale, K., Warner, D. F., Mizrahi, V., Epemolu, O., Scullion, P., Ellis, L., Riley, J., Shishikura, Y., Ferguson, L., Osuna-Cabello, M., Read, K. D. & 10 others, Green, S. R., Lamprecht, D. A., Steyn, A. J. C., Ioerger, T. R., Sacchettini, J., Rhee, K. Y., Arora, K., Barry, C. E., Wyatt, P. G. & Boshoff, H. I. M., 8 Jun 2018, In : ACS Infectious Diseases. 4, 6, p. 954-969 16 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 10 Citations (Scopus)
    135 Downloads (Pure)

    Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and it's newly identified fluorinated analogue 2F-MT-45 with metabolite confirmation in urine samples from known drug users

    McKenzie, C., Sutcliffe, O. B., Read, K., Scullion, S., Epemolu, R., Fletcher, D., Helander, A., Beck, O., Rylski, A., Antonides, L., Riley, J., Smith, S. & Nic Daeid, N., Jul 2018, In : Forensic Toxicology. 36, 2, p. 359-374 16 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 8 Citations (Scopus)
    159 Downloads (Pure)

    Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1

    Bell, M., Foley, D., Naylor, C., Robinson, C., Riley, J., Epemolu, R., Scullion, S., Shishikura, Y., Katz, E., McLean, W., Wyatt, P., Read, K. & Woodland, C., 15 Oct 2018, In : Bioorganic & Medicinal Chemistry Letters. 28, 19, p. 3255-3259 5 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 5 Citations (Scopus)
    199 Downloads (Pure)

    Group-based optimization of potent and cell-active inhibitors of the von Hippel-Lindau (VHL) E3 ubiquitin ligase: structure-activity relationships leading to the chemical probe (2S,4R)-1-((S)-2-(1-cyanocyclopropanecarboxamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide (VH298)

    Soares, P., Gadd, M., Frost, J., Galdeano, C., Ellis, L., Epemolu, R., Rocha, S., Read, K. & Ciulli, A., 2018, In : Journal of Medicinal Chemistry. 61, p. 599-618 19 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 30 Citations (Scopus)
    156 Downloads (Pure)