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Meakin, Paul

Mr, Dr

 https://orcid.org/0000-0002-8553-3863
  • 699 Citations
  • 9 h-Index
20102020

Research output per year

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Projects

Development of a Sporadic Alzheimer's Disease Model (Vacation Scholarship)

Ashford, M. & Meakin, P.

Project: Research

A Pathological Role for BACE1 Actibity in Metabolic Disease?

Ashford, M. & Meakin, P.

Project: Research

Is Plasma Amyloid A Useful Biomarker For Metabolic Disease?

Ashford, M., Khan, F. & Meakin, P.

13/02/17 → 12/08/17

Project: Research

Can Amyloid Processing be Used as a Biomarker for Obesity-Driven Metabolic Disease in Humans

Ashford, M., Dillon, J., Meakin, P. & Palmer, C.

1/06/14 → 1/06/15

Project: Research

The Role of BACE1 in Cardiovascular Health and Disease

Ashford, M., Khan, F. & Meakin, P.

Anonymous Trust

1/06/13 → 31/05/14

Project: Research

Research Output

  • 699 Citations
  • 9 h-Index
  • 12 Article
  • 1 Poster
  • 1 Meeting abstract

Elevated circulating amyloid concentrations in obesity and diabetes promote vascular dysfunction

Meakin, P. J., Coull, B. M., Tuharska, Z., McCaffery, C., Akoumianakis, I., Antoniades, C., Brown, J., Griffin, K. J., Platt, F., Ozber, C. H., Yuldasheva, N. Y., Makava, N., Skromna, A., Prescott, A. R., McNeilly, A. D., Siddiqui, M. K., Palmer, C. N. A., Khan, F. & Ashford, M. L. J., 14 May 2020, In : Journal of Clinical Investigation.

Research output: Contribution to journal › Article

Open Access
File
    • 18 Downloads (Pure)

    Corrigendum to "The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling" [Metab Clin Exp 85 (2018) 59-75]

    Botteri, G., Salvadó, L., Gumà, A., Hamilton, D. L., Meakin, P. J., Montagut, G., Ashford, M. L. J., Ceperuelo-Mallafré, V., Fernández-Veledo, S., Vendrell, J., Calderón-Dominguez, M., Serra, D., Herrero, L., Pizarro, J., Barroso, E., Palomer, X. & Vázquez-Carrera, M., Jul 2019, In : Metabolism: Clinical and Experimental. 96, p. 101-102 2 p.

    Research output: Contribution to journal › Article

    • Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

    Mills, E. L., Ryan, D. G., Prag, H. A., Dikovskaya, D., Menon, D., Zaslona, Z., Jedrychowski, M. P., Costa, A. S. H., Higgins, M., Hams, E., Szpyt, J., Runtsch, M. C., King, M. S., McGouran, J. F., Fischer, R., Kessler, B. M., McGettrick, A. F., Hughes, M. M., Carroll, R. G., Booty, L. M. & 15 others, Knatko, E. V., Meakin, P. J., Ashford, M. L. J., Modis, L. K., Brunori, G., Sévin, D. C., Fallon, P. G., Caldwell, S. T., Kunji, E. R. S., Chouchani, E. T., Frezza, C., Dinkova-Kostova, A. T., Hartley, R. C., Murphy, M. P. & O'Neill, L. A., 5 Apr 2018, In : Nature. 556, 7699, p. 113-117 5 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 228 Citations (Scopus)
    625 Downloads (Pure)

    Small vessels, dementia and chronic diseases: molecular mechanisms and pathophysiology

    Horsburgh, K., Wardlaw, J. M., van Agtmael, T., Allan, S. M., Ashford, M. L. J., Bath, P. M., Brown, R., Berwick, J., Cader, M. Z., Carare, R. O., Davis, J. B., Duncombe, J., Farr, T. D., Fowler, J. H., Goense, J., Granata, A., Hall, C. N., Hainsworth, A. H., Harvey, A., Hawkes, C. A. & 26 others, Joutel, A., Kalaria, R. N., Kehoe, P. G., Lawrence, C. B., Lockhart, A., Love, S., Macleod, M. R., Macrae, I. M., Markus, H. S., McCabe, C., McColl, B. W., Meakin, P. J., Miller, A., Nedergaard, M., O'Sullivan, M., Quinn, T. J., Rajani, R., Saksida, L. M., Smith, C., Smith, K. J., Touyz, R. M., Trueman, R. C., Wang, T., Williams, A., Williams, S. C. R. & Work, L. M., 30 Apr 2018, In : Clinical Science. 132, 8, p. 851-868 18 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 19 Citations (Scopus)
    108 Downloads (Pure)

    The beta secretase BACE1 regulates the expression of the insulin receptor in the liver

    Meakin, P., Mezzapesa, A., Benabou, E., Haas, M., Bonardo, B., Grino, M., Brunel, J-M., Biddinger, S. B., Desbois-Mouthon, C., Govers, R., Ashford, M. L. J. & Peiretti, F., 3 Apr 2018, In : Nature Communications. 9, p. 1-14 14 p., 1306.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 12 Citations (Scopus)
    128 Downloads (Pure)

    Activities

    • 1 Participation in conference

    Diabetes UK Professional Conference 2013

    Paul Meakin (Participant)

    13 Mar 2013 → 15 Mar 2013

    Activity: Participating in or organising an event types › Participation in conference