• 634 Citations
  • 9 h-Index
20102019

Research output per year

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Projects

Research Output

  • 634 Citations
  • 9 h-Index
  • 11 Article
  • 1 Poster
  • 1 Meeting abstract

Corrigendum to "The BACE1 product sAPPβ induces ER stress and inflammation and impairs insulin signaling" [Metab Clin Exp 85 (2018) 59-75]

Botteri, G., Salvadó, L., Gumà, A., Hamilton, D. L., Meakin, P. J., Montagut, G., Ashford, M. L. J., Ceperuelo-Mallafré, V., Fernández-Veledo, S., Vendrell, J., Calderón-Dominguez, M., Serra, D., Herrero, L., Pizarro, J., Barroso, E., Palomer, X. & Vázquez-Carrera, M., Jul 2019, In : Metabolism: Clinical and Experimental. 96, p. 101-102 2 p.

Research output: Contribution to journalArticle

  • Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

    Mills, E. L., Ryan, D. G., Prag, H. A., Dikovskaya, D., Menon, D., Zaslona, Z., Jedrychowski, M. P., Costa, A. S. H., Higgins, M., Hams, E., Szpyt, J., Runtsch, M. C., King, M. S., McGouran, J. F., Fischer, R., Kessler, B. M., McGettrick, A. F., Hughes, M. M., Carroll, R. G., Booty, L. M. & 15 others, Knatko, E. V., Meakin, P. J., Ashford, M. L. J., Modis, L. K., Brunori, G., Sévin, D. C., Fallon, P. G., Caldwell, S. T., Kunji, E. R. S., Chouchani, E. T., Frezza, C., Dinkova-Kostova, A. T., Hartley, R. C., Murphy, M. P. & O'Neill, L. A., 5 Apr 2018, In : Nature. 556, 7699, p. 113-117 5 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 187 Citations (Scopus)
    557 Downloads (Pure)

    Small vessels, dementia and chronic diseases: molecular mechanisms and pathophysiology

    Horsburgh, K., Wardlaw, J. M., van Agtmael, T., Allan, S. M., Ashford, M. L. J., Bath, P. M., Brown, R., Berwick, J., Cader, M. Z., Carare, R. O., Davis, J. B., Duncombe, J., Farr, T. D., Fowler, J. H., Goense, J., Granata, A., Hall, C. N., Hainsworth, A. H., Harvey, A., Hawkes, C. A. & 26 others, Joutel, A., Kalaria, R. N., Kehoe, P. G., Lawrence, C. B., Lockhart, A., Love, S., Macleod, M. R., Macrae, I. M., Markus, H. S., McCabe, C., McColl, B. W., Meakin, P. J., Miller, A., Nedergaard, M., O'Sullivan, M., Quinn, T. J., Rajani, R., Saksida, L. M., Smith, C., Smith, K. J., Touyz, R. M., Trueman, R. C., Wang, T., Williams, A., Williams, S. C. R. & Work, L. M., 30 Apr 2018, In : Clinical Science. 132, 8, p. 851-868 18 p.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 16 Citations (Scopus)
    93 Downloads (Pure)

    The beta secretase BACE1 regulates the expression of the insulin receptor in the liver

    Meakin, P., Mezzapesa, A., Benabou, E., Haas, M., Bonardo, B., Grino, M., Brunel, J-M., Biddinger, S. B., Desbois-Mouthon, C., Govers, R., Ashford, M. L. J. & Peiretti, F., 3 Apr 2018, In : Nature Communications. 9, p. 1-14 14 p., 1306.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 9 Citations (Scopus)
    115 Downloads (Pure)

    Dimethyl fumarate blocks pro-inflammatory cytokine production via inhibition of TLR induced M1 and K63 ubiquitin chain formation

    McGuire, V. A., Ruiz-Zorrilla Diez, T., Emmerich, C. H., Strickson, S., Ritorto, M. S., Sutavani, R. V., Weiβ, A., Houslay, K. F., Knebel, A., Meakin, P. J., Phair, I. R., Ashford, M. L. J., Trost, M. & Arthur, J. S. C., 8 Aug 2016, In : Scientific Reports. 6, p. 1-17 17 p., 31159.

    Research output: Contribution to journalArticle

    Open Access
    File
  • 34 Citations (Scopus)
    241 Downloads (Pure)

    Activities

    • 1 Participation in conference

    Diabetes UK Professional Conference 2013

    Paul Meakin (Participant)
    13 Mar 201315 Mar 2013

    Activity: Participating in or organising an event typesParticipation in conference