Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Paul Wyatt is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Establishment of Cryo-EM Screening Facility At University Of Dundee (Equipment Grant)
Kulathu, Y., Labib, K., Masson, G., Moraga Gonzalez, I., Murray, D., Owen-Hughes, T., Stanley-Wall, N. & Wyatt, P.
1/12/21 → 31/12/26
Project: Research
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Refining the Drug Discovery Paradigm for Schistosomiasis (Joint with the Universities of Aberystwyth & Cardiff)
Gilbert, I., Gray, D., Read, K. & Wyatt, P.
1/10/21 → 1/04/24
Project: Research
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A Platform for Drug Target Deconvolution and Exploitation
Gilbert, I., Horn, D., Pawlowic, M., Wyatt, P. & Wyllie, S.
31/12/20 → 30/12/23
Project: Research
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Dundee - Confidence in Concept 2019
Brady, J., Brady, J., Ferguson, M., Gray, D. & Wyatt, P.
31/03/20 → 1/04/23
Project: Research
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Identification and development of a series of disubstituted piperazines for the treatment of Chagas disease
McGonagle, K., Tarver, G. J., Cantizani, J., Cotillo, I., Dodd, P. G., Ferguson, L., Gilbert, I. H., Marco, M., Miles, T., Naylor, C., Osuna-Cabello, M., Paterson, C., Read, K. D., Pinto, E. G., Riley, J., Scullion, P., Shishikura, Y., Simeons, F., Stojanovski, L., Svensen, N., & 5 others, 5 Aug 2022, In: European Journal of Medicinal Chemistry. 238, 14 p., 114421.Research output: Contribution to journal › Article › peer-review
Open AccessFile24 Downloads (Pure) -
Lysyl-tRNA synthetase, a target for urgently needed M. tuberculosis drugs
Green, S. R., Davis, S. H., Damerow, S., Engelhart, C. A., Mathieson, M., Baragaña, B., Robinson, D. A., Tamjar, J., Dawson, A., Tamaki, F. K., Buchanan, K. I., Post, J., Dowers, K., Shepherd, S. M., Jansen, C., Zuccotto, F., Gilbert, I. H., Epemolu, O., Riley, J., Stojanovski, L., & 25 others, 11 Oct 2022, In: Nature Communications. 13, 12 p., 5992.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)15 Downloads (Pure) -
Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target
Wilson, C., Ray, P., Zuccotto, F., Hernandez, J., Aggarwal, A., Mackenzie, C., Caldwell, N., Taylor, M., Huggett, M., Mathieson, M., Murugesan, D., Smith, A., Davis, S., Cocco, M., Parai, M. K., Acharya, A., Tamaki, F., Scullion, P., Epemolu, O., Riley, J., & 20 others, 13 Jan 2022, In: Journal of Medicinal Chemistry. 65, 1, p. 409-423 15 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)79 Downloads (Pure) -
Refolding of lid subdomain of SARS-CoV-2 nsp14 upon nsp10 interaction releases exonuclease activity
Czarna, A., Plewka, J., Kresik, L., Matsuda, A., Karim, A., Robinson, C., O'Byrne, S., Cunningham, F., Georgiou, I., Wilk, P., Pachota, M., Popowicz, G., Wyatt, P. G., Dubin, G. & Pyrć, K., 4 Aug 2022, In: Structure. 30, 8, p. 1050-1054.E2 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)22 Downloads (Pure) -
Antitubercular 2-Pyrazolylpyrimidinones: Structure-Activity Relationship and Mode-of-Action Studies
Soares de Melo, C., Singh, V., Myrick, A., Simelane, S. B., Taylor, D., Brunschwig, C., Lawrence, N., Schnappinger, D., Engelhart, C. A., Kumar, A., Parish, T., Su, Q., Myers, T. G., Boshoff, H. I. M., Barry, C. E., Sirgel, F. A., van Helden, P. D., Buchanan, K. I., Bayliss, T., Green, S. R., & 6 others, 14 Jan 2021, In: Journal of Medicinal Chemistry. 64, 1, p. 719-740 22 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)324 Downloads (Pure)
Activities
- 1 Invited talk
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In Conversation With...the TB Taskmasters
Ali Floyd (Member), Laura Cleghorn (Invited speaker), Paul Wyatt (Invited speaker) & Lauren Webster (Chair)
9 Nov 2021Activity: Talk or presentation types › Invited talk
Press/Media
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Drug breakthrough in fight against neglected diseases
Paul Wyatt, Alan H. Fairlamb & Michael A. J. Ferguson
1/04/10
1 item of Media coverage
Press/Media: Research