Wyatt, Paul

Professor

  • United Kingdom

20012022
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  • 33 Similar Profiles
Drug Discovery Medicine & Life Sciences
Trypanosoma brucei brucei Medicine & Life Sciences
African Trypanosomiasis Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Parasites Medicine & Life Sciences
Mycobacterium tuberculosis Medicine & Life Sciences
Libraries Medicine & Life Sciences
Visceral Leishmaniasis Medicine & Life Sciences

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Projects 2012 2022

Research Output 2001 2019

A Continuous Flow Strategy for the Facile Synthesis and Elaboration of Semi-Saturated Heterobicyclic Fragments

Luise, N., Wyatt, E. W., Tarver, G. & Wyatt, P., 14 Feb 2019, In : European Journal of Organic Chemistry. 2019, 6, p. 1341-1349 9 p.

Research output: Contribution to journalArticle

fragments
synthesis
Hydrogenation
Quality control
Hydrogen
1 Citation (Scopus)
68 Downloads (Pure)
Open Access
File
Lysosphingolipid Receptors
Drug Discovery
Modulators
Skin
Pharmaceutical Preparations
2 Citations (Scopus)
98 Downloads (Pure)

Diversity-oriented synthesis of bicyclic fragments containing privileged azines

Luise, N. & Wyatt, P. G., 15 Jan 2019, In : Bioorganic & Medicinal Chemistry Letters. 29, 2, p. 248-251 4 p.

Research output: Contribution to journalArticle

Open Access
File
Drug Discovery
Scaffolds
Hydrogen
Biomolecules
Growth
4 Citations (Scopus)

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Thomas, M. G., De Rycker, M., Ajakane, M., Albrecht, S., Álvarez-Pedraglio, A. I., Boesche, M., Brand, S., Campbell, L., Cantizani-Perez, J., Cleghorn, L. A. T., Copley, R. C. B., Crouch, S. D., Daugan, A., Drewes, G., Ferrer, S., Ghidelli-Disse, S., Gonzalez, S., Gresham, S. L., Hill, A. P., Hindley, S. J. & 32 others, Lowe, R. M., MacKenzie, C. J., MacLean, L., Manthri, S., Martin, F., Miguel-Siles, J., Nguyen, V. L., Norval, S., Osuna-Cabello, M., Woodland, A., Patterson, S., Pena, I., Quesada-Campos, M. T., Reid, I. H., Revill, C., Riley, J., Ruiz-Gomez, J. R., Shishikura, Y., Simeons, F. R. C., Smith, A., Smith, V. C., Spinks, D., Stojanovski, L., Thomas, J., Thompson, S., Underwood, T., Gray, D. W., Fiandor, J. M., Gilbert, I. H., Wyatt, P. G., Read, K. D. & Miles, T. J., 14 Feb 2019, In : Journal of Medicinal Chemistry. 62, 3, p. 1180-1202 23 p.

Research output: Contribution to journalArticle

Visceral Leishmaniasis
Leishmania major
Leishmania donovani
Standard of Care
Solubility

Inhibition of CorA dependent Magnesium Homeostasis is cidal in Mycobacterium tuberculosis

Park, Y., Ahn, Y-M., Jonnala, S., Oh, S., Fisher, J. M., Goodwin, M. B., Loerger, T. R., Via, L. E., Bayliss, T., Green, S. R., Ray, P. C., Wyatt, P. G., Barry, C. E. & Boshoff, H. I., 23 Sep 2019, In : Antimicrobial Agents and Chemotherapy. 63, 10, p. 1-14 14 p., e01006-19.

Research output: Contribution to journalArticle

Mycobacterium tuberculosis
Magnesium
Homeostasis
Amides
Symporters

Press / Media

Thesis

To Design and Develop Semi-Saturated and Unsaturated Bicyclic Heterocycles for Fragment-Based Drug Discovery (FBDD) Campaigns

Author: Luise, N., 2019

Supervisor: Wyatt, P. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy