Lis, Pawel

Dr

  • 257 Citations
  • 8 h-Index
20162019
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Fingerprint Dive into the research topics where Pawel Lis is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

Phosphorylation Chemical Compounds
Parkinson Disease Medicine & Life Sciences
Phosphotransferases Medicine & Life Sciences
rab GTP-Binding Proteins Medicine & Life Sciences
Mutation Medicine & Life Sciences
Leucine Medicine & Life Sciences
Proteins Chemical Compounds
Guanosine Triphosphate Medicine & Life Sciences

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Research Output 2016 2019

  • 257 Citations
  • 8 h-Index
  • 10 Article
21 Downloads (Pure)

Membrane association but not identity is required for LRRK2 activation and phosphorylation of Rab GTPases

Gomez, R. C., Wawro, P., Lis, P., Alessi, D. & Pfeffer, S. R., 17 Oct 2019, In : Journal of Cell Biology. 14 p.

Research output: Contribution to journalArticle

Open Access
File
Guanine Nucleotide Dissociation Inhibitors
rab GTP-Binding Proteins
Guanosine Triphosphate
Phosphorylation
Membranes
3 Downloads (Pure)

PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins

Berndsen, K., Lis, P., Yeshaw, W. M., Wawro, P. S., Nirujogi, R., Wightman, M., Macartney, T., Dorward, M., Knebel, A., Tonelli, F., Pfeffer, S. R. & Alessi, D., 12 Nov 2019, In : eLife. 8, p. 1-37 37 p., e50416.

Research output: Contribution to journalArticle

Open Access
File
Phosphoric Monoester Hydrolases
Phosphorylation
Phosphoprotein Phosphatases
Parkinson Disease
rab GTP-Binding Proteins
20 Citations (Scopus)
219 Downloads (Pure)

Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson’s disease kinase

Lis, P., Burel, S., Steger, M., Mann, M., Brown, F., Diez, F., Tonelli, F., Holton, J. L., Winglok Ho, P., Ho, S-L., Chou, M-Y., Polinski, N. K., Martinez, T. N., Davies, P. & Alessi, D. R., 2 Jan 2018, In : Biochemical Journal. 475, 1, p. 1-22 22 p.

Research output: Contribution to journalArticle

Open Access
File
Protein Kinases
Parkinson Disease
Phosphotransferases
Antibodies
Proteins
23 Citations (Scopus)
131 Downloads (Pure)

Interrogating Parkinson's disease LRRK2 kinase pathway activity by assessing Rab10 phosphorylation in human neutrophils

Fan, Y., Howden, A. J. M., Sarhan, A. R., Lis, P., Ito, G., Martinez, T. N., Brockmann, K., Gasser, T., Alessi, D. R. & Sammler, E., 2 Jan 2018, In : Biochemical Journal. 475, 1, p. 23-44 22 p.

Research output: Contribution to journalArticle

Open Access
File
Phosphorylation
Leucine
Parkinson Disease
Neutrophils
Phosphotransferases
16 Citations (Scopus)
103 Downloads (Pure)

Parkinson disease-associated mutations in LRRK2 cause centrosomal defects via Rab8a phosphorylation

Madero-Pérez, J., Fdez, E., Fernández, B., Lara Ordóñez, A. J., Blanca Ramírez, M., Gómez-Suaga, P., Waschbüsch, D., Lobbestael, E., Baekelandt, V., Nairn, A. C., Ruiz-Martínez, J., Aiastui, A., López de Munain, A., Lis, P., Comptdaer, T., Taymans, J-M., Chartier-Harlin, M-C., Beilina, A., Gonnelli, A., Cookson, M. R. & 2 others, Greggio, E. & Hilfiker, S., 23 Jan 2018, In : Molecular Neurodegeneration. 13, 1, p. 1-22 22 p., 3.

Research output: Contribution to journalArticle

Open Access
File
Parkinson Disease
Phosphorylation
Mutation
Centrosome
Phosphotransferases