Cohen, Philip

Professor Sir

  • United Kingdom

1968 …2018
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Phosphorylation Chemical Compounds
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Skeletal Muscle Medicine & Life Sciences

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Research Output 1968 2018

ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism

Nanda, S. K., Nagamori, T., Windheim, M., Amu, S., Aviello, G., Patterson-Kane, J., Arthur, J. S. C., Ley, S. C., Fallon, P. & Cohen, P., 1 Dec 2018, In : Journal of Immunology. 201, 11, p. 3373-3382 10 p.

Research output: Contribution to journalArticle

Colitis
Neoplasms
Myofibroblasts
Cyclooxygenase 2
Ubiquitin

The NEDD8 E3 ligase DCNL5 is phosphorylated by IKK alpha during Toll-like receptor activation

Thomas, Y., Scott, D. C., Kristariyanto, Y. A., Rinehart, J., Clark, K., Cohen, P. & Kurz, T., 29 Jun 2018, In : PLoS ONE. 13, 6, p. 1-19 19 p., e0199197.

Research output: Contribution to journalArticle

Open Access
File
IKappaB kinase
I-kappa B Kinase
Cullin Proteins
Ubiquitin-Protein Ligases
Toll-Like Receptors

Ubiquitin chains as second messengers

Cohen, P., 7 Feb 2018, In : Nature Reviews Molecular Cell Biology. 19, 1 p., 212.

Research output: Contribution to journalArticle

10 Citations

Identification of TBK1 complexes required for the phosphorylation of IRF3 and the production of interferon β

Bakshi, S., Taylor, J., Strickson, S., Macartney, T. & Cohen, P., 15 Mar 2017, In : Biochemical Journal. 474, 7, p. 1163-1174 12 p.

Research output: Contribution to journalArticle

Open Access
File
Interferon Regulatory Factor-3
Phosphorylation
Interferon-beta
Phosphotransferases
Macrophages
3 Citations

Interleukin-1 and TRAF6-dependent activation of TAK1 in the absence of TAB2 and TAB3

Zhang, J., Macartney, T., Peggie, M. & Cohen, P., 26 Jul 2017, In : Biochemical Journal. 474, 13, p. 2235-2248 16 p.

Research output: Contribution to journalArticle

Open Access
File
TNF Receptor-Associated Factor 6
Interleukin-1
Chemical activation
Ubiquitin
Mitogen-Activated Protein Kinase 14

Press / Media

Research reveals how immune cells can be altered to help fight inflammatory diseases

Kristopher Clark, Kirsty MacKenzie, Mark Peggie, Lorna Plater, Patrick G. A. Pedrioli, John Arthur & Philip Cohen

11/10/12

1 item of media coverage

Press/Media: Research

Thesis

An investigation of the activation of protein kinase complexes in the MyD88 signalling network

Author: Zhang, J., 2017

Supervisor: Cohen, P. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

How the ubiquitin system triggers the activation of the MyD88 signalling network

Author: Strickson, S., 2015

Supervisor: Cohen, P. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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