Projects per year
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Projects
The Molecular Mechanisms by which TRAF6 Regulates the Immune System
1/04/18 → 31/03/23
Project: Research
Dissecting how the NLRP3 Inflammasome is Activated to Treat Chronic Inflammatory Diseases
15/10/16 → 14/10/17
Project: Research
Research Output
Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses
Hutchinson, L. D., Darling, N. J., Nicolaou, S., Gori, L., Squair, D. R., Cohen, P., Hill, C. S. & Sapkota, G. P., 22 Jan 2020, In : Cell Death and Disease. 11, p. 1-17 17 p., 49.Research output: Contribution to journal › Article
Open Access
File
Distinct signals and immune cells drive liver pathology and glomerulonephritis in ABIN1[D485N] mice
Nanda, S. K., Petrova, T., Marchesi, F., Gierlinski, M., Razsolkov, M., Lee, K. L., Wright, S. W., Rao, V. R., Cohen, P. & Arthur, J. S. C., 1 Dec 2019, In : Life Science Alliance. 2, 6, p. 1-19 19 p., e201900533.Research output: Contribution to journal › Article
Open Access
File
Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus
Odqvist, L., Jevnikar, Z., Riise, R., Öberg, L., Rhedin, M., Leonard, D., Yrlid, L., Jackson, S., Mattsson, J., Nanda, S., Cohen, P., Knebel, A., Arthur, S., Thörn, K., Svenungsson, E., Jönsen, A., Gunnarsson, I., Tandre, K., Alexsson, A., Kastbom, A. & 10 others, , 12 Jul 2019, In : Annals of the Rheumatic Diseases. 8 p.Research output: Contribution to journal › Article
Open Access
File
4
Citations
(Scopus)
160
Downloads
(Pure)
HOIL-1, an atypical E3 ligase that controls MyD88 signalling by forming ester bonds between ubiquitin and components of the Myddosome
Cohen, P., Kelsall, I. R., Nanda, S. K. & Zhang, J., 5 Oct 2019, In : Advances in Biological Regulation. p. 1-8 8 p., 100666.Research output: Contribution to journal › Article
Open Access
The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells
Kelsall, I., Zhang, R., Knebel, A., Arthur, S. & Cohen, P., 2 Jul 2019, In : Proceedings of the National Academy of Sciences. 116, 27, p. 13293-13298 6 p.Research output: Contribution to journal › Article
Open Access
File
2
Citations
(Scopus)
74
Downloads
(Pure)
Activities
- 1 Public engagement and outreach - media article or participation
The Conversation: How research can lead to some extraordinary (and very unlikely) discoveries
Philip Cohen (Contributor)8 Feb 2017
Activity: Other activity types › Public engagement and outreach - media article or participation
Press / Media
Research reveals how immune cells can be altered to help fight inflammatory diseases
Kristopher Clark, Kirsty MacKenzie, Mark Peggie, Lorna Plater, Patrick G. A. Pedrioli, J. Simon C. Arthur & Philip Cohen
11/10/12
1 item of Media coverage
Press/Media: Research
Thesis
An investigation of the activation of protein kinase complexes in the MyD88 signalling network
Author: Zhang, J., 2017Supervisor: Cohen, P. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
How the ubiquitin system triggers the activation of the MyD88 signalling network
Author: Strickson, S., 2015Supervisor: Cohen, P. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
Structure and Function of the Pseudokinases IRAK2 and IRAK3 and their Potential as Drug Targets
Author: Lange, S. M., 2020Supervisor: Cohen, P. (Supervisor), Kulathu, Y. (Supervisor) & Nelen, M. (External person) (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy