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Cohen, Philip

Professor Sir

  • Research Professor & Personal Chair in Enzymology, MRC PPU
 https://orcid.org/0000-0001-7632-9492

  • United Kingdom

1968 …2020

Research output per year

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Projects

Expanding the Druggable Proteome of Innate Immune Cells - Towards Synthetic Immune Regulation (Fellowship - with Scripps Research Institute)

Cohen, P. & Kavanagh, M.

Wellcome Trust

1/07/18 → 30/06/22

Project: Research

Elucidation of Mechanisms that Restrict Activation of the Innate Immune System to Prevent Inflammatory and Autoimmune Diseases

Arthur, S. & Cohen, P.

Medical Research Council

1/04/18 → 31/03/23

Project: Research

The Molecular Mechanisms by which TRAF6 Regulates the Immune System

Cohen, P.

Wellcome Trust

1/04/18 → 31/03/23

Project: Research

Role of Salt Inducible Kinases in Autoimmunity

Arthur, S. & Cohen, P.

1/04/17 → 30/09/20

Project: Research

Dissecting how the NLRP3 Inflammasome is Activated to Treat Chronic Inflammatory Diseases

Cohen, P. & Nanda, S.

15/10/16 → 14/10/17

Project: Research

Research Output

Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses

Hutchinson, L. D., Darling, N. J., Nicolaou, S., Gori, L., Squair, D. R., Cohen, P., Hill, C. S. & Sapkota, G. P., 22 Jan 2020, In : Cell Death and Disease. 11, p. 1-17 17 p., 49.

Research output: Contribution to journal › Article

Open Access
File
    • 41 Downloads (Pure)

    Distinct signals and immune cells drive liver pathology and glomerulonephritis in ABIN1[D485N] mice

    Nanda, S. K., Petrova, T., Marchesi, F., Gierlinski, M., Razsolkov, M., Lee, K. L., Wright, S. W., Rao, V. R., Cohen, P. & Arthur, J. S. C., 1 Dec 2019, In : Life Science Alliance. 2, 6, p. 1-19 19 p., e201900533.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 14 Downloads (Pure)

    Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

    Odqvist, L., Jevnikar, Z., Riise, R., Öberg, L., Rhedin, M., Leonard, D., Yrlid, L., Jackson, S., Mattsson, J., Nanda, S., Cohen, P., Knebel, A., Arthur, S., Thörn, K., Svenungsson, E., Jönsen, A., Gunnarsson, I., Tandre, K., Alexsson, A., Kastbom, A. & 10 others, Rantapää-Dahlqvist, S., Eloranta, M-L., Syvänen, A-C., Bengtsson, A., Johansson, P., Sandling, J. K., Sjöwall, C., Rönnblom, L., Collins, B. & Vaarala, O., 1 Oct 2019, In : Annals of the Rheumatic Diseases. 78, 10, p. 1363-1370 8 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 6 Citations (Scopus)
    279 Downloads (Pure)

    HOIL-1, an atypical E3 ligase that controls MyD88 signalling by forming ester bonds between ubiquitin and components of the Myddosome

    Cohen, P., Kelsall, I. R., Nanda, S. K. & Zhang, J., 5 Oct 2019, In : Advances in Biological Regulation. p. 1-8 8 p., 100666.

    Research output: Contribution to journal › Article

    Open Access
    • 1 Citation (Scopus)

    The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells

    Kelsall, I., Zhang, R., Knebel, A., Arthur, S. & Cohen, P., 2 Jul 2019, In : Proceedings of the National Academy of Sciences. 116, 27, p. 13293-13298 6 p.

    Research output: Contribution to journal › Article

    Open Access
    File
    • 5 Citations (Scopus)
    89 Downloads (Pure)

    Activities

    • 1 Public engagement and outreach - media article or participation

    The Conversation: How research can lead to some extraordinary (and very unlikely) discoveries

    Philip Cohen (Contributor)

    8 Feb 2017

    Activity: Other activity types › Public engagement and outreach - media article or participation

    Press / Media

    Research reveals how immune cells can be altered to help fight inflammatory diseases

    Kristopher Clark, Kirsty MacKenzie, Mark Peggie, Lorna Plater, Patrick G. A. Pedrioli, J. Simon C. Arthur & Philip Cohen

    11/10/12

    1 item of Media coverage

    Press/Media: Research