Cohen, Philip

Professor Sir

Research Professor & Personal Chair in Enzymology, MRC PPU

United Kingdom

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3 Not started
3 Active
7 Finished

Expanding the Druggable Proteome of Innate Immune Cells - Towards Synthetic Immune Regulation (Fellowship - with Scripps Research Institute)
Cohen, P. & Kavanagh, M.
Wellcome Trust
1/07/18 → 30/06/22
Project: Research
The Molecular Mechanisms by which TRAF6 Regulates the Immune System
Cohen, P.
Wellcome Trust
1/04/18 → 31/03/23
Project: Research
Elucidation of Mechanisms that Restrict Activation of the Innate Immune System to Prevent Inflammatory and Autoimmune Diseases
Arthur, S. & Cohen, P.
Medical Research Council
1/04/18 → 31/03/23
Project: Research
Aref#d: 9354. The establishment of a Post-Genomics and Molecular Interactions Centre at the University of Dundee (Joint Infrastructure Fund)
Cohen, P., Downes, P., Fairlamb, A., Ferguson, M., Hunter, B., Lamond, A., Lilley, D., Norman, D., Watts, C. & Williams, J.
Project: Research
Aref#d: 12419. The establishment of a Post-Genomics and Molecular Interactions Centre at the University of Dundee (Joint Infrastructure Fund - supplement)
Cohen, P., Downes, P., Fairlamb, A., Ferguson, M., Hunter, B., Lamond, A., Lilley, D., Norman, D., Watts, C. & Williams, J.
Project: Research

407 Article
27 Review article
4 Meeting abstract
4 Comment/debate
More

Dimeric structure of the pseudokinase IRAK3 suggests an allosteric mechanism for negative regulation
Lange, S., Nelen, M. I., Cohen, P. & Kulathu, Y., 4 Mar 2021, In: Structure. 29, 3, p. 238-251.e4 14 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
2 Citations (Scopus)

14 Downloads (Pure)
HOIL-1-catalysed, ester-linked ubiquitylation restricts IL-18 signaling in cytotoxic T cells but promotes TLR signalling in macrophages
Petrova, T., Zhang, R., Nanda, S., Figueras-Vadillo, C. & Cohen, P., 1 May 2021, (E-pub ahead of print) In: FEBS Journal. 36 p.
Research output: Contribution to journal › Article › peer-review

Open Access
Nuts and bolts of the Salt-Inducible Kinases (SIKs)
Darling, N. J. & Cohen, P., Apr 2021, In: Biochemical Journal. 478, 7, p. 1377-1397 21 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
1 Downloads (Pure)
Salt-inducible kinases are required for the IL-33-dependent secretion of cytokines and chemokines in mast cells
Darling, N. J., Arthur, J. S. C. & Cohen, P., 2021, In: Journal of Biological Chemistry. 296, 12 p., 100428.
Research output: Contribution to journal › Article › peer-review

Open Access
File
2 Downloads (Pure)
HOIL-1, an atypical E3 ligase that controls MyD88 signalling by forming ester bonds between ubiquitin and components of the Myddosome
Cohen, P., Kelsall, I. R., Nanda, S. K. & Zhang, J., Jan 2020, In: Advances in Biological Regulation. 75, 8 p., 100666.
Research output: Contribution to journal › Article › peer-review

Open Access
File
4 Citations (Scopus)

6 Downloads (Pure)

1 Public engagement and outreach - media article or participation

The Conversation: How research can lead to some extraordinary (and very unlikely) discoveries
Philip Cohen (Contributor)
8 Feb 2017
Activity: Other activity types › Public engagement and outreach - media article or participation

Research reveals how immune cells can be altered to help fight inflammatory diseases
Kristopher Clark, Kirsty MacKenzie, Mark Peggie, Lorna Plater, Patrick G. A. Pedrioli, J. Simon C. Arthur & Philip Cohen
11/10/12
1 item of Media coverage
Press/Media: Research