Research output per year
Research output per year
- 29 results
Search results
-
2021
Kinase drug discovery 20 years after imatinib: progress and future directions
Cohen, P. (Lead / Corresponding author), Cross, D. (Lead / Corresponding author) & Jänne, P. A. (Lead / Corresponding author), Jul 2021, In: Nature Reviews Drug Discovery. 20, p. 551-569 19 p.Research output: Contribution to journal › Review article › peer-review
Open Access611 Citations (Scopus) -
Nuts and bolts of the Salt-Inducible Kinases (SIKs)
Darling, N. J. (Lead / Corresponding author) & Cohen, P., Apr 2021, In: Biochemical Journal. 478, 7, p. 1377-1397 21 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile65 Citations (Scopus)312 Downloads (Pure) -
2017
The role of hybrid ubiquitin chains in the MyD88 and other innate immune signalling pathways
Cohen, P. (Lead / Corresponding author) & Strickson, S., May 2017, In: Cell Death & Differentiation. 24, p. 1153-1159 7 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile91 Citations (Scopus)245 Downloads (Pure) -
2015
Bill Whelan's impact on my life and career
Cohen, P. (Lead / Corresponding author), Dec 2015, In: Molecular Aspects of Medicine. 46, p. 11-13 3 p.Research output: Contribution to journal › Review article › peer-review
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2014
Immune diseases caused by mutations in kinases and components of the ubiquitin system
Cohen, P., Jun 2014, In: Nature Immunology. 15, 6, p. 521-529 9 p.Research output: Contribution to journal › Review article › peer-review
35 Citations (Scopus) -
2010
Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation
Cohen, P., 1 Jan 2010, In: Biochemical Journal. 425, p. 53-54 2 p.Research output: Contribution to journal › Review article › peer-review
60 Citations (Scopus) -
2006
KESTREL: A powerful method for identifying the physiological substrates of protein kinases
Cohen, P. & Knebelt, A., 1 Jan 2006, In: Biochemical Journal. 393, 1, p. 1-6 6 p.Research output: Contribution to journal › Review article › peer-review
68 Citations (Scopus) -
The twentieth century struggle to decipher insulin signalling
Cohen, P., 1 Nov 2006, In: Nature Reviews Molecular Cell Biology. 7, 11, p. 867-873 7 p.Research output: Contribution to journal › Review article › peer-review
188 Citations (Scopus) -
2004
GSK3 inhibitors: Development and therapeutic potential
Cohen, P. & Goedert, M., 1 Jan 2004, In: Nature Reviews Drug Discovery. 3, 6, p. 479-487 9 p.Research output: Contribution to journal › Review article › peer-review
710 Citations (Scopus) -
2001
GSK3 takes centre stage more than 20 years after its discovery
Frame, S. & Cohen, P. (Lead / Corresponding author), 1 Oct 2001, In: Biochemical Journal. 359, 1, p. 1-16 16 p.Research output: Contribution to journal › Review article › peer-review
1322 Citations (Scopus) -
Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms.
Lang, F. & Cohen, P., 1 Jan 2001, In: Science Signaling. 2001, 108, re17.Research output: Contribution to journal › Review article › peer-review
241 Citations (Scopus) -
The renaissance of GSK3
Cohen, P. & Frame, S., 1 Oct 2001, In: Nature Reviews Molecular Cell Biology. 2, 10, p. 769-776 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access1377 Citations (Scopus) -
2000
The regulation of protein function by multisite phosphorylation - A 25 year update
Cohen, P., 1 Dec 2000, In: Trends in Biochemical Sciences. 25, 12, p. 596-601 6 p.Research output: Contribution to journal › Review article › peer-review
947 Citations (Scopus) -
1999
The development and therapeutic potential of protein kinase inhibitors
Cohen, P., Aug 1999, In: Current Opinion in Chemical Biology. 3, 4, p. 459-465 7 p.Research output: Contribution to journal › Review article › peer-review
181 Citations (Scopus) -
1998
Activation of protein kinase B β and γ isoforms by insulin in vivo and by 3-phosphoinositide-dependent protein kinase-1 in vitro: Comparison with protein kinase B α
Walker, K. S. (Lead / Corresponding author), Deak, M., Paterson, A., Hudson, K., Cohen, P. & Alessi, D. R., 1 Apr 1998, In: Biochemical Journal. 331, 1, p. 299-308 10 p.Research output: Contribution to journal › Review article › peer-review
251 Citations (Scopus) -
Mechanism of activation and function of protein kinase B
Alessi, D. R. & Cohen, P., 1 Feb 1998, In: Current Opinion in Genetics and Development. 8, 1, p. 55-62 8 p.Research output: Contribution to journal › Review article › peer-review
683 Citations (Scopus) -
1997
The search for physiological substrates of MAP and SAP kinases in mammalian cells
Cohen, P., 1 Sept 1997, In: Trends in Cell Biology. 7, 9, p. 353-361 9 p.Research output: Contribution to journal › Review article › peer-review
520 Citations (Scopus) -
1991
The actions of cyclic AMP on biosynthetic processes are mediated indirectly by cyclic AMP-dependent protein kinase
Cohen, P. & Grahame Hardie, D., 24 Sept 1991, In: BBA - Molecular Cell Research. 1094, 3, p. 292-299 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access51 Citations (Scopus) -
1990
Okadaic acid: a new probe for the study of cellular regulation
Cohen, P., Holmes, C. F. B. & Tsukitani, Y., Mar 1990, In: Trends in Biochemical Sciences. 15, 3, p. 98-102 5 p.Research output: Contribution to journal › Review article › peer-review
1403 Citations (Scopus) -
The structure and regulation of protein phosphatases.
Cohen, P., 1990, In: Advances in Second Messenger and Phosphoprotein Research. 24, p. 230-235 6 p.Research output: Contribution to journal › Review article › peer-review
39 Citations (Scopus) -
1989
The structure and regulation of protein phosphatases
Cohen, P., Jul 1989, In: Annual Review of Biochemistry. 58, p. 453-508 56 p.Research output: Contribution to journal › Review article › peer-review
2396 Citations (Scopus) -
1988
Protein phosphorylation and hormone action
Cohen, P., 22 Jul 1988, In: Proceedings of the Royal Society B: Biological Sciences. 234, 1275, p. 115-144 30 p.Research output: Contribution to journal › Review article › peer-review
272 Citations (Scopus) -
1983
Protein phosphorylation and the control of glycogen metabolism in skeletal muscle.
Cohen, P., 5 Jul 1983, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 302, 1108, p. 13-25 13 p.Research output: Contribution to journal › Review article › peer-review
56 Citations (Scopus) -
1982
The role of protein phosphorylation in neural and hormonal control of cellular activity
Cohen, P., 15 Apr 1982, In: Nature. 296, 5858, p. 613-620 8 p.Research output: Contribution to journal › Review article › peer-review
791 Citations (Scopus) -
1979
Protein phosphorylation
Cohen, P., 1 Dec 1979, In: Nature. 282, 5736, 1 p.Research output: Contribution to journal › Review article › peer-review
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The hormonal control of glycogen metabolism in mammalian muscle by multivalent phosphorylation
Cohen, P., 1979, In: Biochemical Society Transactions. 7, 3, p. 459-480 22 p.Research output: Contribution to journal › Review article › peer-review
44 Citations (Scopus) -
1978
How does insulin stimulate glycogen synthesis?
Cohen, P., Nimmo, H. G. & Proud, C. G., 1 Dec 1978, In: Biochemical Society Symposia. No.43, p. 69-95 27 p.Research output: Contribution to journal › Review article › peer-review
46 Citations (Scopus) -
1977
Hormonal control of protein phosphorylation.
Nimmo, H. G. & Cohen, P., 1977, In: Advances in Cyclic Nucleotide Research. 8, p. 145-266 122 p.Research output: Contribution to journal › Review article › peer-review
295 Citations (Scopus) -
1974
The role of phosphorylase kinase in the nervous and hormonal control of glycogenolysis in muscle
Cohen, P., 1 Dec 1974, In: Biochemical Society Symposia. Vol. 39, p. 51-73 23 p.Research output: Contribution to journal › Review article › peer-review
38 Citations (Scopus)