Keyphrases
Plasmodium Falciparum
100%
Drug Discovery
99%
Trypanosoma Cruzi (T. cruzi)
90%
Leishmania Donovani
65%
Antileishmanial Activity
54%
Drug Target
54%
Molecular Targets
49%
Malaria
49%
Thermal Proteome Profiling
45%
Pullout
40%
Chagas Disease
40%
Phenotypic Screening
36%
LysR Family
36%
Plasmodium
36%
IC50
34%
Nitroreductase
31%
Cell-free Lysate
27%
In Vitro Assessment
27%
Benzofuran-3(2H)-one
27%
Aryl Aldehydes
27%
Target Engagement
27%
Qi Site
27%
Resistance Mapping
27%
Recombination
27%
Non-genotoxic
27%
Acyl-CoA Synthetase
27%
Human African Trypanosomiasis
27%
5-Nitroimidazoles
27%
Cyclin-dependent Kinase
27%
Mass Spectrometry
27%
Pyridine
27%
Triglycerides
27%
Diaminothiazoles
27%
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)
27%
Protein Synthesis
27%
High-throughput Screening Platform
27%
Cysteine
27%
NTR1
27%
Infectious Diseases
27%
Active Compounds
27%
Apicomplexan
27%
Antitrypanosomal Activity
27%
Lysate
27%
Trypanosoma Brucei
27%
Cytochrome b
27%
In Vitro Activity
27%
Oligo
27%
Bioactivation
27%
Resistance mutations
27%
Parallel Profiling
27%
Pharmacology, Toxicology and Pharmaceutical Science
Drug Discovery
70%
Trypanosoma Cruzi
63%
Chagas Disease
40%
IC50
38%
Antitrypanosomal
36%
Antimalarial Agent
36%
Infection
36%
Nitroreductase
33%
Amastigote
29%
Proteasome
27%
High-Throughput Screening
27%
Pyridine Derivative
27%
Trypanosoma Brucei
27%
4 Nitroimidazole
27%
Nagana
27%
Cysteine
27%
Apicomplexa
27%
Bioactivation
27%
Cyclin Dependent Kinase
27%
Leishmania donovani
27%
Cytochrome B
27%
Comet Assay
22%
Lead Compound
22%
Disease
22%
Molecular Target
22%
Cytotoxicity
19%
Mouse
19%
Leishmania
19%
Malate Dehydrogenase (Decarboxylating)
18%
Bovine
18%
Electrophile
18%
Infectious Agent
15%
Pharmacokinetics
13%
Nitroquinoline Derivative
13%
Trypanosoma
13%
Luciferase
13%
Coenzyme Q - Cytochrome C Reductase
13%
Trypomastigote
13%
Cytotoxicity Assay
13%
Visceral Leishmaniasis
13%
Chymotrypsin
9%
Sulfoxide
9%
Fexinidazole
9%
Ames Test
9%
Proteasome Inhibitor
9%
Enzyme Inhibition
9%
Eflornithine
9%
Benznidazole
9%
Trypanosoma Vivax
9%
Toxoplasma gondii
9%