Wolf, Roland

Professor

  • 21428 Citations
  • 87 h-Index
1977 …2021
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Fingerprint Dive into the research topics where Roland Wolf is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Cytochrome P-450 Enzyme System Medicine & Life Sciences
Glutathione Transferase Medicine & Life Sciences
Cytochrome P-450 CYP2D6 Medicine & Life Sciences
Liver Medicine & Life Sciences
NADPH-Ferrihemoprotein Reductase Medicine & Life Sciences
Pharmaceutical Preparations Medicine & Life Sciences
Enzymes Medicine & Life Sciences
Genes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2012 2021

Research Output 1977 2019

23 Downloads (Pure)

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

Henderson, C. J., Kapelyukh, Y., Scheer, N., Rode, A., McLaren, A., MacLeod, K., Lin, D., Wright, J., Stanley, L. A. & Wolf, C. R., Jun 2019, In : Drug Metabolism and Disposition. 47, 6, p. 601-615 15 p.

Research output: Contribution to journalArticle

Open Access
File
Drug Interactions
Clinical Trials
Pharmaceutical Preparations
Pharmacokinetics
Cytochrome P-450 CYP3A
50 Downloads (Pure)

Application of hepatic cytochrome b5/P450 reductase null (HBRN) mice to study the role of cytochrome b5 in the cytochrome P450-mediated bioactivation of the anticancer drug ellipticine

Reed, L., Indra, R., Mrizova, I., Moserova, M., Schmeiser, H. H., Wolf, C. R., Henderson, C. J., Stiborova, M., Phillips, D. H. & Arlt, V. M., 1 Mar 2019, In : Toxicology and Applied Pharmacology. 366, p. 64-74 11 p.

Research output: Contribution to journalArticle

Open Access
File
ellipticine
Cytochromes b5
NADPH-Ferrihemoprotein Reductase
Cytochrome P-450 Enzyme System
Oxidoreductases
1 Citation (Scopus)
52 Downloads (Pure)

Constitutive androstane receptor 1 is constitutively bound to chromatin and ‘primed’ for transactivation in hepatocytes

McMahon, M., Ding, S., Acosta-Jimenez, L., Terranova, R., Gerard, M-A., Vitobello, A., Moggs, J. G., Henderson, C. J. & Wolf, C. R., 1 Jan 2019, In : Molecular Pharmacology. 95, 1, p. 97-105 9 p.

Research output: Contribution to journalArticle

Open Access
File
Transcriptional Activation
Chromatin
Hepatocytes
Xenobiotics
constitutive androstane receptor
Open Access
Cytochrome P-450 CYP1A2
Cytochrome P-450 CYP1A1
Knockout Mice
Pharmaceutical Preparations
Enzyme Inhibitors
12 Citations (Scopus)
72 Downloads (Pure)

Discovery of common and rare genetic risk variants for colorectal cancer

Huyghe, J. R., Bien, S. A., Harrison, T. A., Kang, H. M., Chen, S., Schmit, S. L., Conti, D. V., Qu, C., Jeon, J., Edlund, C. K., Greenside, P., Wainberg, M., Schumacher, F. R., Smith, J. D., Levine, D. M., Nelson, S. C., Sinnott-Armstrong, N. A., Albanes, D., Alonso, M. H., Anderson, K. & 179 others, Arnau-Collell, C., Arndt, V., Bamia, C., Banbury, B. L., Baron, J. A., Berndt, S. I., Bézieau, S., Bishop, D. T., Boehm, J., Boeing, H., Brenner, H., Brezina, S., Buch, S., Buchanan, D. D., Burnett-Hartman, A., Butterbach, K., Caan, B. J., Campbell, P. T., Carlson, C. S., Castellví-Bel, S., Chan, A. T., Chang-Claude, J., Chanock, S. J., Chirlaque, M-D., Cho, S. H., Connolly, C. M., Cross, A. J., Cuk, K., Curtis, K. R., de la Chapelle, A., Doheny, K. F., Duggan, D., Easton, D. F., Elias, S. G., Elliott, F., English, D. R., Feskens, E. J. M., Figueiredo, J. C., Fischer, R., FitzGerald, L. M., Forman, D., Gala, M., Gallinger, S., Gauderman, W. J., Giles, G. G., Gillanders, E., Gong, J., Goodman, P. J., Grady, W. M., Grove, J. S., Gsur, A., Gunter, M. J., Haile, R. W., Hampe, J., Hampel, H., Harlid, S., Hayes, R. B., Hofer, P., Hoffmeister, M., Hopper, J. L., Hsu, W-L., Huang, W-Y., Hudson, T. J., Hunter, D. J., Ibañez-Sanz, G., Idos, G. E., Ingersoll, R., Jackson, R. D., Jacobs, E. J., Jenkins, M. A., Joshi, A. D., Joshu, C. E., Keku, T. O., Key, T. J., Kim, H. R., Kobayashi, E., Kolonel, L. N., Kooperberg, C., Kühn, T., Küry, S., Kweon, S-S., Larsson, S. C., Laurie, C. A., Le Marchand, L., Leal, S. M., Lee, S. C., Lejbkowicz, F., Lemire, M., Li, C. I., Li, L., Lieb, W., Lin, Y., Lindblom, A., Lindor, N. M., Ling, H., Louie, T. L., Männistö, S., Markowitz, S. D., Martín, V., Masala, G., McNeil, C. E., Melas, M., Milne, R. L., Moreno, L., Murphy, N., Myte, R., Naccarati, A., Newcomb, P. A., Offit, K., Ogino, S., Onland-Moret, N. C., Pardini, B., Parfrey, P. S., Pearlman, R., Perduca, V., Pharoah, P. D. P., Pinchev, M., Platz, E. A., Prentice, R. L., Pugh, E., Raskin, L., Rennert, G., Rennert, H. S., Riboli, E., Rodríguez-Barranco, M., Romm, J., Sakoda, L. C., Schafmayer, C., Schoen, R. E., Seminara, D., Shah, M., Shelford, T., Shin, M-H., Shulman, K., Sieri, S., Slattery, M. L., Southey, M. C., Stadler, Z. K., Stegmaier, C., Su, Y-R., Tangen, C. M., Thibodeau, S. N., Thomas, D. C., Thomas, S. S., Toland, A. E., Trichopoulou, A., Ulrich, C. M., Van Den Berg, D. J., van Duijnhoven, F. J. B., Van Guelpen, B., van Kranen, H., Vijai, J., Visvanathan, K., Vodicka, P., Vodickova, L., Vymetalkova, V., Weigl, K., Weinstein, S. J., White, E., Win, A. K., Wolf, C. R., Wolk, A., Woods, M. O., Wu, A. H., Zaidi, S. H., Zanke, B. W., Zhang, Q., Zheng, W., Scacheri, P. C., Potter, J. D., Bassik, M. C., Kundaje, A., Casey, G., Moreno, V., Abecasis, G. R., Nickerson, D. A., Gruber, S. B., Hsu, L. & Peters, U., 1 Jan 2019, In : Nature Genetics. 51, 1, p. 76-87 12 p.

Research output: Contribution to journalArticle

Open Access
File
Colorectal Neoplasms
Long Noncoding RNA
Preclinical Drug Evaluations
Genome-Wide Association Study
Haplotypes

Activities 2001 2006

  • 5 Participation in conference

14th North American ISSX Meeting

Roland Wolf (Participant)
22 Oct 200626 Oct 2006

Activity: Participating in or organising an event typesParticipation in conference

Newcastle Pathology 2005: 3rd Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain and Ireland

Roland Wolf (Participant)
5 Jul 20058 Jul 2005

Activity: Participating in or organising an event typesParticipation in conference

British Society for Investigative Dermatology Annual Meeting

Roland Wolf (Participant)
7 Apr 20039 Apr 2003

Activity: Participating in or organising an event typesParticipation in conference

184th Meeting of the Pathological Society of Great Britain and Ireland

Roland Wolf (Participant)
2 Jul 20025 Jul 2002

Activity: Participating in or organising an event typesParticipation in conference

51st Annual Meeting of the American Society of Human Genetics

Roland Wolf (Participant)
12 Oct 200116 Oct 2001

Activity: Participating in or organising an event typesParticipation in conference

Press / Media

Gene helps predict which ovarian cancer sufferers will benefit most from chemotherapy

Gillian Smith, Michael Ng, C Simon Herrington, Michelle Ferguson & Roland Wolf

19/09/12

1 item of Media coverage

Press/Media: Research

Thesis

Catalytic and non-catalytic mechanisms involved in Glutathione S-transferase Pi mediated cytoprotection

Author: McGarry, D., 2012

Supervisor: Henderson, C. J. (Supervisor) & Wolf, C. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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Metabolic Factors Determining Outcome in Chemotherapy: Studies with Pazopanib

Author: Sharp, S. L., 2014

Supervisor: Wolf, C. (Supervisor) & Henderson, C. J. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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microRNA expression in colorectal tumours: identification of novel mechanisms of gene regulation

Author: Amankwatia, E. B., 2014

Supervisor: Smith, G. (Supervisor) & Wolf, C. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

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