Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Precision Control Of Protein Dosage In Vivo (joint with University of Edinburgh)
Wolf, R. (Investigator)
1/11/22 → 31/10/27
Project: Research
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Aref#d: 19888. Personalised Medicine Programme
Wolf, R. (Investigator)
1/12/07 → 30/06/26
Project: Research
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8HUM PK characterization and TB project support
Read, K. (Investigator) & Wolf, R. (Investigator)
Bill and Melinda Gates Foundation
17/06/23 → 16/10/25
Project: Research
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ADOPT: Appropriate Dosing To Optimise Personalised Cancer Treatments
Ferguson, M. (Investigator), Henderson, C. (Investigator), Proby, C. (Investigator) & Wolf, R. (Investigator)
1/10/20 → 30/09/21
Project: Research
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AKT/mTOR as a targetable hub to overcome multimodal resistance to EGFR inhibitors in oesophageal squamous cell carcinoma
Spender, L. C., Watt, D. M., Baxter, M. A., Shuttleworth, M. K., Walker, K., Savage, A. R., Clements, H. A., Kapelyukh, Y., Bray, S. E., King, S. I., Wolf, C. R., Inman, G. J., Walsh, S. V., Blyth, K. & Petty, R. D. (Lead / Corresponding author), 21 Sept 2025, In: British Journal of Cancer. 133, 5, p. 709-722 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Downloads (Pure) -
Application of a mouse model humanized for cytochrome P450–mediated drug metabolism to predict drug-drug interactions between a peptide and small molecule drugs
Kapelyukh, Y., Gabel-Jensen, C., MacLeod, A. K., Coquelin, K.-S. D., Stojanovski, L., Frame, L., Tavendale, A., Henderson, C. J., Read, K. D., Wolf, C. R. (Lead / Corresponding author) & Säll, C. (Lead / Corresponding author), Oct 2025, In: Drug Metabolism and Disposition. 53, 10, 14 p., 100153.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Integration of in vivo stress reporters with transcription profiling to define chemical mixtures mechanisms of toxicity, including trans-generational effects
Inesta-Vaquera, F. (Lead / Corresponding author), Qi, W., Dimova-Vasileva, S., Campbell, G. J., Ferro, F., Meehan, R., Pennings, S. & Wolf, C. R., 1 Nov 2025, In: Chemico-Biological Interactions. 421, 11 p., 111699.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The potent human CAR activator CITCO is a non-genotoxic hepatic tumour-promoting agent in humanised constitutive androstane receptor mice but not in wild-type animals
Henderson, C. J., McLaren, A., MacLeod, A. K., Lin, D., Cameron, A., Chatham, L. R., Moggs, J. G., Inesta-Vaquera, F., Thomson, J. P., Meehan, R., Chakravarty, P., Wolf, R. (Lead / Corresponding author) & Schwarz, M., May 2025, In: Archives of Toxicology. 99, p. 2197-2210 14 p., 109464.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)26 Downloads (Pure) -
Use of an Extensively Humanised Mouse Model to Predict the Risk of Drug-Drug Interactions in Patients Receiving Dexamethasone
George, J., Chalmers, J., Coquelin, K.-S., Frame, L., Henderson, C. J., Kapelyukh, Y., Lang, C. C., Read, K. D., Stanley, L. A. & Wolf, C. R. (Lead / Corresponding author), Feb 2025, In: Journal of Pharmacology and Experimental Therapeutics. 392, 2, 100053.Research output: Contribution to journal › Article › peer-review
3 Citations (Scopus)
Activities
- 5 Participation in conference
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14th North American ISSX Meeting
Wolf, R. (Participant)
22 Oct 2006 → 26 Oct 2006Activity: Participating in or organising an event types › Participation in conference
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Newcastle Pathology 2005: 3rd Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain and Ireland
Wolf, R. (Participant)
5 Jul 2005 → 8 Jul 2005Activity: Participating in or organising an event types › Participation in conference
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British Society for Investigative Dermatology Annual Meeting
Wolf, R. (Participant)
7 Apr 2003 → 9 Apr 2003Activity: Participating in or organising an event types › Participation in conference
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184th Meeting of the Pathological Society of Great Britain and Ireland
Wolf, R. (Participant)
2 Jul 2002 → 5 Jul 2002Activity: Participating in or organising an event types › Participation in conference
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51st Annual Meeting of the American Society of Human Genetics
Wolf, R. (Participant)
12 Oct 2001 → 16 Oct 2001Activity: Participating in or organising an event types › Participation in conference
Press/Media
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Gene helps predict which ovarian cancer sufferers will benefit most from chemotherapy
Smith, G., Ng, M., Herrington, C. S., Ferguson, M. & Wolf, R.
19/09/12
1 item of Media coverage
Press/Media: Research