Keyphrases
Cytochrome P450 (CYP450)
79%
Glutathione S-transferase
55%
Cytochrome P450 Reductase
40%
Metabolism
37%
Cytochrome P450 2D6 (CYP2D6)
34%
P450
29%
Cytochrome P450 Enzymes
27%
GSTP1
27%
Null Mice
26%
Liver
25%
Drug Metabolism
22%
Cytochrome P450 1A1 (CYP1A1)
20%
Polymorphism
19%
Glutathione S-transferase pi
19%
Colorectal Cancer
19%
Isoenzymes
17%
Cytochrome b5
16%
P450s
16%
Hepatic Cytochrome P450
14%
Reductase
13%
Mouse Liver
13%
Humanized
13%
Cytochrome P450 3A4 (CYP3A4)
13%
Tumor
12%
Constitutive Androstane Receptor
12%
Mouse Model
12%
Human Cytochrome P450
12%
Phenobarbital
11%
Drug Interactions
11%
Nuclear Factor Erythroid 2-related Factor 2 (Nrf2)
11%
Gene Expression
11%
Pregnane X Receptor
10%
Anticancer Drugs
10%
Human Liver
10%
Oxidative Stress
10%
Glutathione
9%
Drug-metabolizing Enzymes
9%
Cytochrome P450 2E1 (CYP2E1)
9%
Xenobiotics
9%
Humanized Mouse Model
9%
Cytochrome P450 1A2 (CYP1A2)
9%
Peroxisome Proliferator-activated Receptor
9%
Benzo(a)pyrene
8%
Drug Disposition
8%
Gene Family
8%
Humanized Mice
8%
Drug Development
8%
Wild Mice
8%
Cytochrome P-450 CYP2D6
8%
Detoxification
8%
Pharmacology, Toxicology and Pharmaceutical Science
Cytochrome P450
100%
Glutathione
45%
Transferase
39%
Knockout Mouse
31%
Cytochrome P450 Reductase
30%
Neoplasm
24%
Drug Metabolism
23%
Isoenzyme
23%
Glutathione Transferase P1
22%
Mouse Model
21%
Malignant Neoplasm
21%
CYP2D6
18%
Messenger RNA
17%
Unspecific Monooxygenase
15%
Xenobiotic Agent
15%
Cytochrome
15%
Carcinogen
15%
Detoxication
14%
Cytochrome B5
14%
Reduced Nicotinamide Adenine Dinucleotide Phosphate
14%
Cytochrome P450 1A1
13%
Glutathione Transferase
13%
Phenobarbital
12%
Anticarcinogen
12%
Constitutive Androstane Receptor
11%
Carcinogenesis
10%
Disease
10%
Pregnane X Receptor
10%
Wild Type Mouse
9%
Antioxidant
9%
Drug Metabolizing Enzyme
9%
Benzo(a)pyrene
9%
Peroxisome Proliferator Activated Receptor
9%
Transcription Factor Nrf2
9%
Biological Marker
9%
Oxidoreductase
9%
Amino Acid
8%
Pharmacokinetics
8%
CYP1A2
8%
Drug Development
8%
Drug-Drug Interaction
8%
CYP2E1
7%
Receptor
7%
Drug Discovery
7%
Cytochrome P450 Isoenzyme
7%
Colorectal Carcinoma
7%
Transgenic Mouse
6%
Drug Resistance
6%
CYP3A4
6%
Western Blot
6%
Biochemistry, Genetics and Molecular Biology
Cytochrome P450
66%
Enzyme
38%
Glutathione S-Transferase
34%
Metabolic Pathway
26%
CYP2D6
24%
Cytochrome P450 Reductase
20%
Unspecific Monooxygenase
11%
Oxidoreductase
11%
Drug Metabolism
11%
Knockout Mouse
11%
Multigene Family
10%
Genetics
10%
Reductase
10%
Cytochrome
10%
CYP3A4
10%
Oxygenase
9%
Active Site
9%
Mouse Model
9%
Wild Type
9%
Genotyping
8%
Carcinogenesis
8%
P53
8%
Messenger RNA
7%
Homeostasis
7%
Oxidative Stress
7%
Gene Expression
6%
Hepatocyte
6%
Constitutive Androstane Receptor
6%
Amino Acids
6%
Isoenzyme
6%
Enzyme Specificity
5%
Allele
5%
Colon
5%
Adaptive Response
5%
Isozyme
5%