• 5343 Citations
  • 36 h-Index
1991 …2020

Research output per year

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Research Output

2020
Open Access
File
1 Citation (Scopus)
54 Downloads (Pure)
Open Access
File
11 Downloads (Pure)

Effects of once-weekly semaglutide vs once-daily canagliflozin on body composition in type 2 diabetes: a substudy of the SUSTAIN 8 randomised, controlled clinical trial

McCrimmon, R., Catarig, A-M., Frias, J. P., Lausvig, N. L., le Roux, C. W., Thielke, D. & Lingvay, I., 1 Mar 2020, In : Diabetologia. 63, 3, p. 473-485 13 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
57 Downloads (Pure)

Experimental Models of Impaired Hypoglycaemia-Associated Counter-Regulation

Sankar, A., Khodai, T., McNeilly, A. D., McCrimmon, R. J. & Luckman, S. M., 17 Jun 2020, In : Trends in Endocrinology and Metabolism. 13 p.

Research output: Contribution to journalReview article

Open Access
Open Access
File
3 Downloads (Pure)
Open Access
File
17 Downloads (Pure)

Prescribing paradigm shift? Applying the 2019 European Society of Cardiology-led guidelines on ‘diabetes, pre-diabetes, and cardiovascular disease’ to assess eligibility for sodium-glucose co-transporter-2 inhibitors or glucagon-like peptide-1 receptor agonists as first-line monotherapy (or add-on to metformin monotherapy) in type 2 diabetes in Scotland

Caparrotta, T. M., Blackbourn, L. A. K., McGurnaghan, S. J., Chalmers, J., Lindsay, R., McCrimmon, R., McKnight, J., Wild, S., Petrie, J. R., Philip, S., McKeigue, P. M., Webb, D. J., Sattar, N., Colhoun, H. M. & Scottish Diabetes Research Network Epidemiology Group, 24 Jun 2020, In : Diabetes Care.

Research output: Contribution to journalArticle

Open Access
File
10 Downloads (Pure)

Reducing the burden of hypoglycaemia in people with diabetes through increased understanding: design of the Hypoglycaemia Redefining Solutions for Better Lives (Hypo-RESOLVE) project

de Galan, B. E., McCrimmon, R. J., Ibberson, M., Heller, S. R., Choudhary, P., Pouwer, F., Speight, J., Carlton, J., Pieber, T. R., Rosilio, M., Tack, C. J., Müllenborn, M. & Hypo-RESOLVE Consortium, 22 May 2020, In : Diabetic Medicine. 37, 6, p. 1066-1073 8 p.

Research output: Contribution to journalArticle

Open Access
File
54 Downloads (Pure)

Socio-economic status and mortality in people with type 1 diabetes in Scotland 2006-2015: a retrospective cohort study

Campbell, R. A. S., Colhoun, H. M., Kennon, B., McCrimmon, R. J., Sattar, N., McKnight, J., Wild, S. H. & Scottish Diabetes Research Network Epidemiology Group, 22 Jan 2020, In : Diabetic Medicine. 8 p.

Research output: Contribution to journalArticle

Time Trends in Deaths Before Age 50 Years in People with Type 1 Diabetes: a nationwide analysis from Scotland 2004–2017

O’Reilly, J. E., Blackbourn, L., Caparrotta, T., Jeyam, A., Kennon, B., Leese, G. P., Lindsay, R. S., McCrimmon, R. J., McGurnaghan, S. J., McKeigue, P. M., McKnight, J. A., Petrie, J. R., Philip, S., Sattar, N., Wild, S. H., Colhoun, H. M. & Scottish Diabetes Research Network Epidemiology Group, 1 Aug 2020, In : Diabetologia. 63, 8, p. 1626-1636 11 p.

Research output: Contribution to journalArticle

Open Access
File
18 Downloads (Pure)
2019

CD44 contributes to hyaluronan-mediated insulin resistance in skeletal muscle of high fat-fed C57BL/6 mice

Hasib, A., Hennayake, C., Bracy, D. P., Bugler-Lamb, A-R., Lantier, L., Khan, F., Ashford, M., McCrimmon, R., Wasserman, D. H. & Kang, L., Dec 2019, In : American Journal of Physiology, Endocrinology and Metabolism. 317, 6, p. E973-E983 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial

Gerstein, H. C., Colhoun, H. M., Dagenais, G. R., Diaz, R., Lakshmanan, M., Pais, P., Probstfield, J., Riesmeyer, J. S., Riddle, M. C., Rydén, L., Xavier, D., Atisso, C. M., Dyal, L., Hall, S., Rao-Melacini, P., Wong, G., Avezum, A., Basile, J., Chung, N., Conget, I. & 17 others, Cushman, W. C., Franek, E., Hancu, N., Hanefeld, M., Holt, S., Jansky, P., Keltai, M., Lanas, F., Leiter, L. A., Lopez-Jaramillo, P., Cardona Munoz, E. G., Pirags, V., Pogosova, N., Raubenheimer, P. J., Shaw, J. E., Sheu, W. H-H. & Temelkova-Kurktschiev, T., 13 Jul 2019, In : Lancet. 394, 10193, p. 121-130 10 p.

Research output: Contribution to journalArticle

270 Citations (Scopus)

Effect of Hypoglycemia on Inflammatory Responses and the Response to Low Dose Endotoxemia in Humans

Iqbal, A., Prince, L. R., Novodvorsky, P., Bernjak, A., Thomas, M. R., Birch, L., Lambert, D., Kay, L. J., Wright, F. J., Macdonald, I. A., Jacques, R. M., Storey, R. F., McCrimmon, R. J., Francis, S., Heller, S. R. & Sabroe, I., Apr 2019, In : Journal of Clinical Endocrinology and Metabolism. 104, 4, p. 1187-1199 13 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
104 Downloads (Pure)

Efficacy and safety of once-weekly semaglutide versus daily canagliflozin as add-on to metformin in patients with type 2 diabetes (SUSTAIN 8): a double-blind, phase 3b, randomised controlled trial

Lingvay, I., Catarig, A-M., Frias, J. P., Kumar, H., Lausvig, N. L., le Roux, C. W., Thielke, D., Viljoen, A. & McCrimmon, R., Nov 2019, In : The Lancet: Diabetes and Endocrinology. 7, 11, p. 834-844 11 p.

Research output: Contribution to journalArticle

Open Access
File
17 Citations (Scopus)
123 Downloads (Pure)

Glycaemic benefit of iGlarLixi in insulin-naive type 2 diabetes patients with high HbA1c or those with inadequate glycaemic control on two oral antihyperglycaemic drugs in the LixiLan-O randomized trial

Davies, M. J., Russell-Jones, D., Barber, T. M., Lavalle-González, F. J., Galstyan, G. R., Zhu, D., Baxter, M., Dessapt-Baradez, C. & McCrimmon, R. J., Aug 2019, In : Diabetes, Obesity & Metabolism. 21, 8, p. 1967-1972 6 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
11 Downloads (Pure)

Glycaemic control trends in people with Type 1 diabetes in Scotland 2004-2016

Scottish Diabetes Research Network Epidemiology Group, Mair, C., Wulaningsih, W., Jeyam, A., McGurnaghan, S., Blackbourn, L. A. K., Kennon, B., Leese, G., Lindsay, R., McCrimmon, R., McKnight, J. A., Petrie, J. R., Sattar, N., Wild, S. H., Conway, N., Craigie, I., Robertson, K., Bath, L., McKeigue, P. M. & Colhoun, H. M., 1 Aug 2019, In : Diabetologia. 62, 8, p. 1375-1384 10 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
124 Downloads (Pure)

Hypoglycaemia, cardiovascular disease, and mortality in diabetes: epidemiology, pathogenesis, and management

1 May 2019, In : The Lancet Diabetes and Endocrinology. 7, 5, p. 385-396 12 p.

Research output: Contribution to journalReview article

25 Citations (Scopus)

Implementation of Basal-Bolus Therapy in Type 2 Diabetes: A Randomized Controlled Trial Comparing Bolus Insulin Delivery Using an Insulin Patch with an Insulin Pen

Calibra Study Group, Bergenstal, R. M., Peyrot, M., Dreon, D. M., Aroda, V. R., Bailey, T. S., Brazg, R. L., Frias, J. P., Johnson, M. L., Klonoff, D. C., Kruger, D. F., Ramtoola, S., Rosenstock, J., Serusclat, P., Weinstock, R. S., Naik, R. G., Shearer, D. M., Zraick, V. & Levy, B. L., 7 May 2019, In : Diabetes Technology and Therapeutics. 21, 5, p. 273-285 13 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
98 Downloads (Pure)

Inhibition of NFAT Signaling Restores Microvascular Endothelial Function in Diabetic Mice

Garcia-Vaz, E., McNeilly, A. D., Berglund, L. M., Ahmad, A., Gallagher, J. R., Dutius Andersson, A-M., McCrimmon, R. J., Zetterqvist, A. V., Gomez, M. F. & Khan, F., Dec 2019, In : Diabetes. 68, 12, p. 424-435 12 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
186 Downloads (Pure)

Investigating the Relationship Between Type 2 Diabetes and Dementia Using Electronic Medical Records in the GoDARTS Bioresource

Doney, A. S. F., Bonney, W., Jefferson, E., Walesby, K. E., Bittern, R., Trucco, E., Connelly, P., McCrimmon, R. J. & Palmer, C. N. A., Oct 2019, In : Diabetes Care. 42, 10, p. 1973-1980 8 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
124 Downloads (Pure)

Loss of CRMP2 O-GlcNAcylation leads to reduced novel object recognition performance in mice

Muha, V., Williamson, R., Hills, R., McNeilly, A., McWilliams, T. G., Alonso, J., Schimpl, M., Leney, A. C., Heck, A. J. R., Sutherland, C., Read, K., McCrimmon, R., Brooks, S. P. & van Aalten, D., 27 Nov 2019, In : Open Biology. 9, 11, p. 1-15 15 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
69 Downloads (Pure)

The effect of dapagliflozin on glycaemic control and other cardiovascular disease risk factors in type 2 diabetes mellitus: a real-world observational study

Scottish Diabetes Research Network Epidemiology Group, McGurnaghan, S. J., Brierley, L., Caparrotta, T. M., McKeigue, P. M., Blackbourn, L. A. K., Wild, S. H., Leese, G., McCrimmon, R., McKnight, J. A., Pearson, E., Petrie, J. R., Sattar, N. & Colhoun, H. M., Apr 2019, In : Diabetologia. 62, 4, p. 621-632 12 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
120 Downloads (Pure)
2018

Amputation-free survival in 17,353 people at high risk for foot ulceration in diabetes: a national observational study

Scottish Diabetes Research Network Epidemiology Group, Vadiveloo, T., Jeffcoate, W., Donnan, P. T., Colhoun, H. C., McGurnaghan, S., Wild, S., McCrimmon, R. & Leese, G. P., Dec 2018, In : Diabetologia. 61, 12, p. 2590-2597 8 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
159 Downloads (Pure)

Bace1-dependent amyloid processing regulates hypothalamic leptin sensitivity in obese mice

Meakin, P. J., Jalicy, S. M., Montagut, G., Allsop, D. J. P., Cavellini, D. L., Irvine, S. W., McGinley, C., Liddell, M. K., McNeilly, A. D., Parmionova, K., Liu, Y-R., Bailey, C. S. L., Dale, J. K., Heisler, L. K., McCrimmon, R. J. & Ashford, M. L. J., 8 Jan 2018, In : Scientific Reports. 8, 1, p. 55 16 p., 55.

Research output: Contribution to journalArticle

Open Access
File
8 Citations (Scopus)
178 Downloads (Pure)

Cardiovascular Disease, Cancer, and Mortality Among People With Type 2 Diabetes and Alcoholic or Nonalcoholic Fatty Liver Disease Hospital Admission

Wild, S. H., Walker, J. J., Morling, J. R., McAllister, D. A., Colhoun, H. M., Farran, B., McGurnaghan, S., McCrimmon, R., Read, S. H., Sattar, N., Byrne, C. D. & Scottish Diabetes Research Network Epidemiology Group, Feb 2018, In : Diabetes Care. 41, 2, p. 341-347 7 p., dc171590.

Research output: Contribution to journalArticle

Open Access
File
29 Citations (Scopus)
198 Downloads (Pure)

Cardiovascular disease prevalence and risk factor prevalence in Type 2 diabetes: a contemporary analysis

McGurnaghan, S., Blackbourn, L. A. K., Mocevic, E., Panton, U. H., McCrimmon, R. J., Sattar, N., Wild, S. & Colhoun, H. M., 10 Oct 2018, In : Diabetic Medicine. 36, 6, p. 718-725 8 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
77 Downloads (Pure)
Open Access
File
42 Citations (Scopus)
147 Downloads (Pure)

Impaired hypoglycaemia awareness in type 1 diabetes: lessons from the lab

McNeilly, A. D. & McCrimmon, R. J., 1 Apr 2018, In : Diabetologia. 61, 4, p. 743-750 8 p.

Research output: Contribution to journalReview article

Open Access
File
5 Citations (Scopus)
186 Downloads (Pure)

Incident ischaemic stroke and Type 2 diabetes: trends in incidence and case fatality in Scotland 2004-2013

Read, S. H., McAllister, D. A., Colhoun, H. M., Farran, B., Fischbacher, C., Kerssens, J. J., Leese, G. P., Lindsay, R. S., McCrimmon, R. J., McGurnaghan, S., Philip, S., Sattar, N., Wild, S. H. & Scottish Diabetes Research Network Epidemiology Group, Jan 2018, In : Diabetic Medicine. 35, 1, p. 99-106 8 p.

Research output: Contribution to journalArticle

Open Access
File
7 Citations (Scopus)
151 Downloads (Pure)

Probability of Achieving Glycemic Control with Basal Insulin in Patients with Type 2 Diabetes in Real-World Practice in the USA

Blonde, L., Meneghini, L., Peng, X. V., Boss, A., Rhee, K., Shaunik, A., Kumar, S., Balodi, S., Brulle-Wohlhueter, C. & McCrimmon, R. J., Jun 2018, In : Diabetes Therapy. 9, 3, p. 1347-1358 12 p.

Research output: Contribution to journalArticle

Open Access
File
11 Citations (Scopus)
201 Downloads (Pure)

SGLT inhibitor adjunct therapy in type 1 diabetes

McCrimmon, R. & Henry, R. R., Oct 2018, In : Diabetologia. 61, 10, p. 2126-2133 8 p.

Research output: Contribution to journalReview article

Open Access
File
30 Citations (Scopus)
180 Downloads (Pure)

Type 2 diabetes, socioeconomic status and life expectancy in Scotland (2012-2014): a population-based observational study

Walker, J., Colhoun, H., Livingstone, S., McCrimmon, R., Petrie, J., Sattar, N., Wild, S. & Scottish Diabetes Research Network Epidemiology Group, Jan 2018, In : Diabetologia. 61, 1, p. 108-116 9 p.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
206 Downloads (Pure)
2017

AMP-activated protein kinase activator A-769662 increases intracellular calcium and ATP release from astrocytes in an AMPK-independent manner

Vlachaki Walker, J. M., Robb, J. L., Cruz, A. M., Malhi, A., Weightman Potter, P. G., Ashford, M. L. J., McCrimmon, R. J., Ellacott, K. L. J. & Beall, C., 21 Apr 2017, In : Diabetes, Obesity & Metabolism. 19, 7, p. 997-1005 9 p.

Research output: Contribution to journalArticle

Open Access
File
10 Citations (Scopus)
254 Downloads (Pure)
Open Access
File
8 Citations (Scopus)
195 Downloads (Pure)

Efficacy and safety of dapagliflozin in patients with inadequately controlled type 1 diabetes (DEPICT-1): 24 week results from a multicentre, double-blind, phase 3, randomised controlled trial

Dandona, P., Mathieu, C., Phillip, M., Hansen, L., Griffen, S. C., Tschöpe, D., Thorén, F., Xu, J., Langkilde, A. M. & DEPICT-1 Investigators, Nov 2017, In : The Lancet: Diabetes and Endocrinology. 5, 11, p. 864-876 13 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)

Exercise management in type 1 diabetes: a consensus statement

Riddell, M. C., Gallen, I. W., Smart, C. E., Taplin, C. E., Adolfsson, P., Lumb, A. N., Kowalski, A., Rabasa-Lhoret, R., McCrimmon, R. J., Hume, C., Annan, F., Fournier, P. A., Graham, C., Bode, B., Galassetti, P., Jones, T. W., Millán, I. S., Heise, T., Peters, A. L., Petz, A. & 1 others, Laffel, L. M., May 2017, In : The Lancet: Diabetes and Endocrinology. 5, 5, p. 377-390 14 p.

Research output: Contribution to journalReview article

Open Access
File
207 Citations (Scopus)
2400 Downloads (Pure)
Open Access
File
9 Citations (Scopus)
272 Downloads (Pure)

Oleate induces KATP channel-dependent hyperpolarisation in mouse hypothalamic glucose-excited neurones without altering cellular energy charge

Dadak, S., Beall, C., Vlachaki Walker, J. M., Soutar, M. P. M., McCrimmon, R. J. & Ashford, M. L. J., 27 Mar 2017, In : Neuroscience. 346, p. 29-42 14 p.

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
110 Downloads (Pure)

RD Lawrence Lecture 2015. Old habits are hard to break: lessons from the study of hypoglycaemia

McCrimmon, R. J., Feb 2017, In : Diabetic Medicine. 34, 2, p. 148-155 8 p.

Research output: Contribution to journalReview article

Open Access
File
7 Citations (Scopus)
210 Downloads (Pure)
Open Access
File
19 Citations (Scopus)
181 Downloads (Pure)

Risk of acute kidney injury and survival in patients treated with Metformin: an observational cohort study

Bell, S., Farran, B., McGurnaghan, S., McCrimmon, R., Leese, G. P., Petrie, J. R., McKeigue, P. M., Sattar, N., Wild, S., McKnight, J., Lindsay, R., Colhoun, H. M. & Looker, H., 19 May 2017, In : BMC Nephrology. 18, p. 1-8 8 p., 163.

Research output: Contribution to journalArticle

Open Access
File
20 Citations (Scopus)
158 Downloads (Pure)
2016

Chronic Activation of γ2 AMPK Induces Obesity and Reduces β Cell Function

Yavari, A., Stocker, C. J., Ghaffari, S., Wargent, E. T., Steeples, V., Czibik, G., Pinter, K., Bellahcene, M., Woods, A., Martínez de Morentin, P. B., Cansell, C., Lam, B. Y. H., Chuster, A., Petkevicius, K., Nguyen-Tu, M-S., Martinez-Sanchez, A., Pullen, T. J., Oliver, P. L., Stockenhuber, A., Nguyen, C. & 34 others, Lazdam, M., O'Dowd, J. F., Harikumar, P., Tóth, M., Beall, C., Kyriakou, T., Parnis, J., Sarma, D., Katritsis, G., Wortmann, D. D. J., Harper, A. R., Brown, L. A., Willows, R., Gandra, S., Poncio, V., de Oliveira Figueiredo, M. J., Qi, N. R., Peirson, S. N., McCrimmon, R., Gereben, B., Tretter, L., Fekete, C., Redwood, C., Yeo, G. S. H., Heisler, L. K., Rutter, G. A., Smith, M. A., Withers, D. J., Carling, D., Sternick, E. B., Arch, J. R. S., Cawthorne, M. A., Watkins, H. & Ashrafian, H., 10 May 2016, In : Cell Metabolism. 23, 5, p. 821-835 16 p.

Research output: Contribution to journalArticle

Open Access
File
48 Citations (Scopus)
262 Downloads (Pure)

Chronic exposure to KATP channel openers results in attenuated glucose sensing in hypothalamic GT1-7 neurons

Hathorne, E., Hamilton, D. L., Findlay, J. A., Beall, C., McCrimmon, R. J. & Ashford, M. L. J., Dec 2016, In : Neuropharmacology. 111, p. 212-222 11 p.

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
176 Downloads (Pure)

Erratum to: Trends in type 2 diabetes incidence and mortality in Scotland between 2004 and 2013

Read, S. H., Kerssens, J. J., McAllister, D. A., Colhoun, H. M., Fischbacher, C. M., Lindsay, R. S., McCrimmon, R. J., McKnight, J. A., Petrie, J. R., Sattar, N., Wild, S. H. & Scottish Diabetes Research Network Epidemiology Group, Nov 2016, In : Diabetologia. 59, 11, p. 2492 1 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
34 Citations (Scopus)
163 Downloads (Pure)

In vivo inhibition of nuclear factor of activated t cells (NFAT) restores microvascular endothelial function in diabetic mice

Garcia-Vaz, E., McNeilly, A., Gallagher, J., McCrimmon, R., Khan, F. & Gomez, M. F., Sep 2016, In : Atherosclerosis. 252, p. e244-e245 2 p., EAS16-0988.

Research output: Contribution to journalArticle

Open Access
File
15 Citations (Scopus)
137 Downloads (Pure)

Patterns of weight change after the diagnosis of type 2 diabetes in Scotland and their relationship with glycaemic control, mortality and cardiovascular outcomes: a retrospective cohort study

Aucott, L. S., Philip, S., Avenell, A., Afolabi, E., Sattar, N., Wild, S. & Scottish Diabetes Research Network Epidemiology Group, 26 Jul 2016, In : BMJ Open. 6, 7, p. 1-14 14 p., e010836.

Research output: Contribution to journalArticle

Open Access
File
13 Citations (Scopus)
132 Downloads (Pure)
Open Access
File
4 Citations (Scopus)
168 Downloads (Pure)