O'Neill, Sandra

Research output

Research output per year 2012 2021

• 61 Citations
• 3 h-Index
• 5 Article

Research output per year

Research output per year

Search results

• 2021

  Inhibiting Mycobacterium tuberculosis CoaBC by targeting an allosteric site

  Mendes, V., Green, S. R., Evans, J. C., Hess, J., Blaszczyk, M., Spry, C., Bryant, O., Cory-Wright, J., Chan, D. S-H., Torres, P. H. M., Wang, Z., Nahiyaan, N., O'Neill, S., Damerow, S., Post, J., Bayliss, T., Lynch, S. L., Coyne, A. G., Ray, P. C., Abell, C. & 6 others, Rhee, K. Y., Boshoff, H. I. M., Barry, C. E., Mizrahi, V., Wyatt, P. G. & Blundell, T. L., 8 Jan 2021, In: Nature Communications. 12, 12 p., 143.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • tuberculosis
  • Allosteric Site
  • Coenzyme A
  • coenzymes
  • Mycobacterium tuberculosis
  10 Downloads (Pure)
• 2020

  Development of a High-Throughput Screening Assay to Identify Inhibitors of the Major M17-Leucyl Aminopeptidase from Trypanosoma cruzi Using RapidFire Mass Spectrometry

  Izquierdo, M., Lin, D., O'Neill, S., Zoltner, M., Webster, L., Hope, A., Gray, D. W., Field, M. C. & González-Bacerio, J., 1 Oct 2020, In: SLAS Discovery. 25, 9, p. 1064-1071 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Leucyl Aminopeptidase
  • High-Throughput Screening Assays
  • Mass spectrometry
  • Trypanosoma cruzi
  • Assays
  1 Citation (Scopus)
• 2019

  Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis

  Baragaña, B., Forte, B., Choi, R., Nakazawa Hewitt, S., Bueren-Calabuig, J. A., Pisco, J. P., Peet, C., Dranow, D. M., Robinson, D. A., Jansen, C., Norcross, N. R., Vinayak, S., Anderson, M., Brooks, C. F., Cooper, C. A., Damerow, S., Delves, M., Dowers, K., Duffy, J., Edwards, T. E. & 57 others, Hallyburton, I., Horst, B. G., Hulverson, M. A., Ferguson, L., Jiménez-Díaz, M. B., Jumani, R. S., Lorimer, D. D., Love, M. S., Maher, S., Matthews, H., McNamara, C. W., Miller, P., O'Neill, S., Ojo, K. K., Osuna-Cabello, M., Pinto, E., Post, J., Riley, J., Rottmann, M., Sanz, L. M., Scullion, P., Sharma, A., Shepherd, S. M., Shishikura, Y., Simeons, F. R. C., Stebbins, E. E., Stojanovski, L., Straschil, U., Tamaki, F. K., Tamjar, J., Torrie, L. S., Vantaux, A., Witkowski, B., Wittlin, S., Yogavel, M., Zuccotto, F., Angulo-Barturen, I., Sinden, R., Baum, J., Gamo, F-J., Mäser, P., Kyle, D. E., Winzeler, E. A., Myler, P. J., Wyatt, P. G., Floyd, D., Matthews, D., Sharma, A., Striepen, B., Huston, C. D., Gray, D. W., Fairlamb, A. H., Pisliakov, A. V., Walpole, C., Read, K. D., Van Voorhis, W. C. & Gilbert, I. H., 2 Apr 2019, In: Proceedings of the National Academy of Sciences. 116, 14, p. 7015-7020 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Lysine-tRNA Ligase
  • Cryptosporidiosis
  • cladosporin
  • Cryptosporidium parvum
  • Malaria
  33 Citations (Scopus)

  238 Downloads (Pure)
• 2014

  Fragment screening reveals salicylic hydroxamic acid as an inhibitor of Trypanosoma brucei GPI GlcNAc-PI de-N-acetylase

  Urbaniak, M. D., Capes, A. S., Crossman, A., O'Neill, S., Thompson, S., Gilbert, I. H. & Ferguson, M. A. J., 31 Mar 2014, In: Carbohydrate Research. 387, p. 54-58 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase
  • Salicylic acid
  • Hydroxamic Acids
  • Salicylic Acid
  • Trypanosoma brucei brucei
  4 Citations (Scopus)

  123 Downloads (Pure)
• 2012

  A static-cidal assay for Trypanosoma brucei to aid hit prioritisation for progression into drug discovery programmes

  De Rycker, M., O'Neill, S., Joshi, D., Campbell, L., Gray, D. W. & Fairlamb, A. H., 29 Nov 2012, In: PLoS Neglected Tropical Diseases. 6, 11, p. e1932

  Research output: Contribution to journal › Article › peer-review

  • Trypanosoma brucei brucei
  • Trypanosoma
  • Drug Discovery
  • African Trypanosomiasis
  • Disease Vectors
  23 Citations (Scopus)