Brown, Sara

Professor, Wellcome Trust Senior Research Fellow, Professor of Molecular and Genetic Dermatology

  • 3197 Citations
  • 27 h-Index
20032024
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Research Output 2003 2019

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Article
2019
1 Citation (Scopus)

EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis

Elias, M. S., Wright, S. C., Remenyi, J., Abbott, J. C., Bray, S. E., Cole, C., Edwards, S., Gierlinski, M., Glok, M., McGrath, J. A., Nicholson, W. V., Paternoster, L., Prescott, A. R., Have, S. T., Whitfield, P. D., Lamond, A. I. & Brown, S. J., Aug 2019, In : Journal of Allergy and Clinical Immunology. 144, 2, p. 470-481 12 p.

Research output: Contribution to journalArticle

Open Access
Atopic Dermatitis
Skin
Genome-Wide Association Study
Keratinocytes
Skin Diseases
16 Citations (Scopus)
91 Downloads (Pure)

Evidence of a causal relationship between body mass index and psoriasis: A mendelian randomization study

Budu-Aggrey, A., Brumpton, B., Tyrrell, J., Watkins, S., Modalsli, E. H., Celis-Morales, C., Ferguson, L. D., Vie, G. Å., Palmer, T., Fritsche, L. G., Løset, M., Nielsen, J. B., Zhou, W., Tsoi, L. C., Wood, A. R., Jones, S. E., Beaumont, R., Saunes, M., Romundstad, P. R., Siebert, S. & 8 others, McInnes, I. B., Elder, J. T., Davey Smith, G., Frayling, T. M., Åsvold, B. O., Brown, S. J., Sattar, N. & Paternoster, L., 31 Jan 2019, In : PLoS Medicine. 16, 1, p. 1-18 18 p., e1002739.

Research output: Contribution to journalArticle

Open Access
File
Random Allocation
Psoriasis
Body Mass Index
Mendelian Randomization Analysis
Skin Diseases
22 Downloads (Pure)
Open Access
File
Organoids
Proteomics
Skin
Keratinocytes
Caspase 14
5 Citations (Scopus)
31 Downloads (Pure)

Human and computational models of atopic dermatitis: A review and perspectives by an expert panel of the International Eczema Council

Eyerich, K., Brown, S. J., Perez White, B. E., Tanaka, R. J., Bissonette, R., Dhar, S., Bieber, T., Hijnen, D. J., Guttman-Yassky, E., Irvine, A., Thyssen, J. P., Vestergaard, C., Werfel, T., Wollenberg, A., Paller, A. S. & Reynolds, N. J., 1 Jan 2019, In : Journal of Allergy and Clinical Immunology. 143, 1, p. 36-45 10 p.

Research output: Contribution to journalArticle

Open Access
File
Eczema
Atopic Dermatitis
Therapeutics
Biological Models
Precision Medicine
1 Citation (Scopus)
28 Downloads (Pure)

Position Statement on Atopic Dermatitis in Sub-Saharan Africa: current status and roadmap

Schmid-Grendelmeier, P., Takaoka, R., Ahogo, K. C., Belachew, W. A., Brown, S. J., Correia, J. C., Correia, M., Degboe, B., Dorizy-Vuong, V., Faye, O., Fuller, L. C., Grando, K., Hsu, C., Kayitenkore, K., Lunjani, N., Ly, F., Mahamadou, G., Manuel, R. C. F., Kebe Dia, M., Masenga, E. J. & 7 others, Muteba Baseke, C., Ouedraogo, A. N., Rapelanoro Rabenja, F., Su, J., Teclessou, J. N., Todd, G. & Taïeb, A., Nov 2019, In : Journal of the European Academy of Dermatology and Venereology. 33, 11, p. 2019-2028 10 p.

Research output: Contribution to journalArticle

Open Access
File
Africa South of the Sahara
Atopic Dermatitis
Patient Education
Dermatology
Skin Diseases
35 Downloads (Pure)
Open Access
File
Organoids
Crosstalk
Keratinocytes
Proteomics
Skin
Environmental Exposure
Atopic Dermatitis
Mutation
Gene-Environment Interaction
Sample Size
2018
5 Citations (Scopus)

A randomized controlled trial protocol assessing the effectiveness, safety and cost-effectiveness of methotrexate vs. ciclosporin in the treatment of severe atopic eczema in children: the TREatment of severe Atopic eczema Trial (TREAT)

Guy's and St Thomas' NHS Foundation Trust, Irvine, A. D., Jones, A. P., Beattie, P., Baron, S., Browne, F., Ashoor, F., O'Neill, L., Rosala-Hallas, A., Sach, T., Spowart, C., Taams, L., Walker, C., Wan, M., Webb, N., Williamson, P. & Flohr, C., Dec 2018, In : British Journal of Dermatology. 179, 6, p. 1297-1306 10 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Clinical Protocols
Methotrexate
Cyclosporine
Cost-Benefit Analysis
31 Citations (Scopus)
171 Downloads (Pure)

Identification of atopic dermatitis subgroups in children from two longitudinal birth cohorts

Paternoster, L., Savenije, O. E. M., Heron, J., Evans, D. M., Vonk, J. M., Brunekreef, B., Wijga, A. H., Henderson, A. J., Koppelman, G. H. & Brown, S. J., Mar 2018, In : Journal of Allergy and Clinical Immunology. 141, 3, p. 964-971 8 p.

Research output: Contribution to journalArticle

Open Access
File
Atopic Dermatitis
Parturition
Exanthema
Cohort Studies
Mutation
6 Citations (Scopus)
44 Downloads (Pure)

Research Techniques Made Simple: Transepidermal Water Loss Measurement as a Research Tool

Alexander, H., Brown, S., Danby, S. & Flohr, C., Nov 2018, In : Journal of Investigative Dermatology. 138, 11, p. 2295-2300.e1 7 p.

Research output: Contribution to journalArticle

Open Access
File
Skin
Research Design
Water
Research
Microclimate
10 Citations (Scopus)
155 Downloads (Pure)

The micro-evolution and epidemiology of Staphylococcus aureus colonization during atopic eczema disease flare

Harkins, C., Pettigrew, K. A., Oravcová, K., Gardner, J., Hearn, R. M. R., Rice, D., Mather, A. E., Parkhill, J., Brown, S., Proby, C. & Holden, M. T. G., Feb 2018, In : Journal of Investigative Dermatology. 138, 2, p. 336-343 8 p.

Research output: Contribution to journalArticle

Open Access
File
Epidemiology
Atopic Dermatitis
Staphylococcus aureus
Population
Pathogens
2017
6 Citations (Scopus)
163 Downloads (Pure)

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis

Naeem, A. S., Tommasi, C., Cole, C., Brown, S. J., Zhu, Y., Way, B., Willis Owen, S. A. G., Moffatt, M., Cookson, W. O., Harper, J. I., Di, W. L., Brown, S. J., Reinheckel, T. & O'Shaughnessy, R. F. L., Apr 2017, In : Journal of Allergy and Clinical Immunology. 139, 4, p. 1228-1241 14 p.

Research output: Contribution to journalArticle

Open Access
File
Cathepsin H
Thymoma
Atopic Dermatitis
Oncogenes
Skin
24 Citations (Scopus)
122 Downloads (Pure)

Effectiveness and cost-effectiveness of daily all-over-body application of emollient during the first year of life for preventing atopic eczema in high-risk children (The BEEP trial): protocol for a randomised controlled trial

Chalmers, J. R., Haines, R. H., Mitchell, E. J., Thomas, K. S., Brown, S. J., Ridd, M. J., Lawton, S., Simpson, E. L., Cork, M. J., Sach, T. H., Bradshaw, L. E., Montgomery, A. A., Boyle, R. J. & Williams, H. C., 21 Jul 2017, In : Trials. 18, p. 1-11 11 p., 343.

Research output: Contribution to journalArticle

Open Access
File
Emollients
Atopic Dermatitis
Clinical Protocols
Cost-Benefit Analysis
Randomized Controlled Trials
11 Citations (Scopus)
120 Downloads (Pure)

Randomised controlled trial of silk therapeutic garments for the management of atopic eczema in children: the CLOTHES trial

Thomas, K. S., Bradshaw, L. E., Sach, T. H., Cowdell, F., Batchelor, J. M., Lawton, S., Harrison, E. F., Haines, R. H., Ahmed, A., Dean, T., Burrows, N. P., Pollock, I., Buckley, H. K., Williams, H. C., Llewellyn, J., Crang, C., Grundy, J. D., Guiness, J., Gribbin, A., Wake, E. V. & 3 others, Mitchell, E. J., Brown, S. J. & Montgomery, A. A., Apr 2017, In : Health Technology Assessment. 21, 16, p. 1-260 260 p.

Research output: Contribution to journalArticle

Open Access
File
Clothing
Silk
Atopic Dermatitis
Eczema
Randomized Controlled Trials
18 Citations (Scopus)
113 Downloads (Pure)

Silk garments plus standard care compared with standard care for treating eczema in children: A randomised, controlled, observer-blind, pragmatic trial (CLOTHES Trial)

Thomas, K. S., Bradshaw, L. E., Sach, T. H., Batchelor, J. M., Lawton, S., Harrison, E. F., Haines, R. H., Ahmed, A., Williams, H. C., Dean, T., Burrows, N. P., Pollock, I., Llewellyn, J., Crang, C., Grundy, J. D., Guiness, J., Gribbin, A., Mitchell, E. J., Cowdell, F., Brown, S. J. & 2 others, Montgomery, A. A. & UK Dermatology Clinical Trials Network’s CLOTHES Trial Team, 11 Apr 2017, In : PLoS Medicine. 14, 4, p. 1-23 23 p., e1002280.

Research output: Contribution to journalArticle

Open Access
File
Pragmatic Clinical Trials
Clothing
Silk
Eczema
Atopic Dermatitis
57 Citations (Scopus)
132 Downloads (Pure)

When does atopic dermatitis warrant systemic therapy? Recommendations from an expert panel of the International Eczema Council

Simpson, E. L., Bruin-Weller, M., Flohr, C., Ardern-Jones, M. R., Barbarot, S., Deleuran, M., Bieber, T., Vestergaard, C., Brown, S. J., Cork, M. J., Drucker, A. M., Eichenfield, L. F., Foelster-Holst, R., Guttman-Yassky, E., Nosbaum, A., Reynolds, N. J., Silverberg, J. I., Schmitt, J., Seyger, M. M. B., Spuls, P. I. & 9 others, Stalder, J-F., Su, J. C., Takaoka, R., Traidl-Hoffmann, C., Thyssen, J. P., van der Schaft, J., Wollenberg, A., Irvine, A. D. & Paller, A. S., Oct 2017, In : Journal of the American Academy of Dermatology. 77, 4, p. 623-633 11 p.

Research output: Contribution to journalArticle

Open Access
File
Eczema
Atopic Dermatitis
Therapeutics
Quality of Life
Decision Making
2016
22 Citations (Scopus)
132 Downloads (Pure)

Propranolol in the treatment of infantile haemangiomas: lessons from the European Propranolol In the Treatment of Complicated Haemangiomas (PITCH) Taskforce survey

Wedgeworth, E., Glover, M., Irvine, A. D., Neri, I., Baselga, E., Clayton, T. H., Beattie, P. E., Bjerre, J. V., Burrows, N. P., Foelster-Holst, R., Hedelund, L., Hernandez-Martin, A., Audrain, H., Bhate, K., Brown, S. J., Baryschpolec, S., Darne, S., Durack, A., Dvorakova, V., Gach, J. & 35 others, Goldstraw, N., Goodyear, H., Grabczynska, S., Greenblatt, D., Halpern, J., Hearn, R. M. R., Hoey, S., Hughes, B., Jayaraj, R., Johansson, E. K., Lam, M., Leech, S., O'Regan, G. M., Morrison, D., Porter, W., Ramesh, R., Schill, T., Shaw, L., Taylor, A. E. M., Taylor, R., Thomson, J., Tiffin, P., Tsakok, M., Janmohamed, S. R., Laguda, B., McPherson, T., Oranje, A. P., Patrizi, A., Ravenscroft, J. C., Shahidullah, H., Solman, L., Svensson, A., Wahlgren, C. F., Hoeger, P. H. & Flohr, C., Mar 2016, In : British Journal of Dermatology. 174, 3, p. 594-601 8 p.

Research output: Contribution to journalArticle

Open Access
File
Hemangioma
Propranolol
Therapeutics
Odds Ratio
Confidence Intervals
2015
7 Citations (Scopus)
114 Downloads (Pure)

A multi-centre, parallel group superiority trial of silk therapeutic clothing compared to standard care for the management of eczema in children (CLOTHES Trial): study protocol for a randomised controlled trial

Harrison, E. F., Haines, R. H., Cowdell, F., Sach, T. H., Dean, T., Pollock, I., Burrows, N. P., Buckley, H., Batchelor, J., Williams, H. C., Lawton, S., Brown, S. J., Bradshaw, L. E., Ahmed, A., Montgomery, A. A., Mitchell, E. J. & Thomas, K. S., 2 Sep 2015, In : Trials. 16, 12 p., 390.

Research output: Contribution to journalArticle

Open Access
File
Clothing
Silk
Eczema
Standard of Care
Clinical Protocols
144 Citations (Scopus)
278 Downloads (Pure)

Atopic dermatitis increases the effect of exposure to peanut antigen in dust on peanut sensitization and likely peanut allergy

Brough, H. A., Liu, A. H., Sicherer, S., Makinson, K., Douiri, A., Brown, S. J., Stephens, A. C., McLean, W. H. I., Turcanu, V., Wood, R. A., Jones, S. M., Burks, W., Dawson, P., Stablein, D., Sampson, H. & Lack, G., Jan 2015, In : Journal of Allergy and Clinical Immunology. 135, 1, p. 164-170.e4 11 p.

Research output: Contribution to journalArticle

Open Access
File
Peanut Hypersensitivity
Atopic Dermatitis
Dust
Antigens
Environmental Exposure
56 Citations (Scopus)

Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

Baurecht, H., Hotze, M., Brand, S., Büning, C., Cormican, P., Corvin, A., Ellinghaus, D., Ellinghaus, E., Esparza-Gordillo, J., Fölster-Holst, R., Franke, A., Gieger, C., Hubner, N., Illig, T., Irvine, A. D., Kabesch, M., Lee, Y. A. E., Lieb, W., Marenholz, I., McLean, W. H. I. & 19 others, Morris, D. W., Mrowietz, U., Nair, R., Nöthen, M. M., Novak, N., O'Regan, G. M., PAGE Consortium, Schreiber, S., Smith, C., Strauch, K., Stuart, P. E., Trembath, R., Tsoi, L. C., Weichenthal, M., Barker, J., Elder, J. T., Weidinger, S., Cordell, H. J. & Brown, S. J., 8 Jan 2015, In : American Journal of Human Genetics. 96, 1, p. 104-120 17 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Psoriasis
Genome
Chromosomes
Alleles
6 Citations (Scopus)
102 Downloads (Pure)

Identification of translational dermatology research priorities in the U.K. Results of an electronic Delphi exercise

Healy, E., Brown, S. J., Langan, S. M., Nicholls, S. G., Shams, K. & Reynolds, N. J., 14 Oct 2015, In : British Journal of Dermatology. 173, 5, p. 1191-1198 8 p.

Research output: Contribution to journalArticle

Open Access
File
Translational Medical Research
Dermatology
Exercise
Research
Skin Diseases
2014
344 Citations (Scopus)
160 Downloads (Pure)

Emollient enhancement of the skin barrier from birth offers effective atopic dermatitis prevention

Simpson, E. L., Chalmers, J. R., Hanifin, J. M., Thomas, K. S., Cork, M. J., McLean, W. H. I., Brown, S. J., Chen, Z., Chen, Y. & Williams, H. C., Oct 2014, In : Journal of Allergy and Clinical Immunology. 134, 4, p. 818-823 6 p.

Research output: Contribution to journalArticle

Open Access
File
Emollients
Atopic Dermatitis
Parturition
Skin
Incidence
69 Citations (Scopus)
146 Downloads (Pure)

Filaggrin-stratified transcriptomic analysis of pediatric skin identifies mechanistic pathways in patients with atopic dermatitis

Cole, C., Kroboth, K., Schurch, N. J., Sandilands, A., Sherstnev, A., O'Regan, G. M., Watson, R. M., McLean, W. H. I., Barton, G. J., Irvine, A. D. & Brown, S. J., Jul 2014, In : Journal of Allergy and Clinical Immunology. 134, 1, p. 82-91 10 p.

Research output: Contribution to journalArticle

Open Access
File
Atopic Dermatitis
Pediatrics
Skin
Genotype
Extracellular Space
12 Citations (Scopus)
333 Downloads (Pure)
Open Access
File
RNA Sequence Analysis
Expressed Sequence Tags
3' Untranslated Regions
3' untranslated regions
sequence analysis
136 Citations (Scopus)
113 Downloads (Pure)

Peanut allergy: effect of environmental peanut exposure in children with filaggrin loss-of-function mutations

Brough, H. A., Simpson, A., Makinson, K., Hankinson, J., Brown, S., Douiri, A., Belgrave, D. C. M., Penagos, M., Stephens, A. C., McLean, W. H. I., Turcanu, V., Nicolaou, N., Custovic, A. & Lack, G., Oct 2014, In : Journal of Allergy and Clinical Immunology. 134, 4, p. 867-875.e1 10 p.

Research output: Contribution to journalArticle

Open Access
File
Peanut Hypersensitivity
Environmental Exposure
Mutation
Dust
Skin Tests
2013
94 Citations (Scopus)

A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis

Weidinger, S., Willis-Owen, S. A. G., Kamatani, Y., Baurecht, H., Morar, N., Liang, L., Edser, P., Street, T., Rodriguez, E., O'Regan, G. M., Beattie, P., Fölster-Holst, R., Franke, A., Novak, N., Fahy, C. M., Winge, M. C. G., Kabesch, M., Illig, T., Heath, S., Söderhäll, C. & 13 others, Melén, E., Pershagen, G., Kere, J., Bradley, M., Lieden, A., Nordenskjold, M., Harper, J. I., McLean, W. H. I., Brown, S. J., Cookson, W. O. C., Lathrop, G. M., Irvine, A. D. & Moffatt, M. F., Dec 2013, In : Human Molecular Genetics. 22, 23, p. 4841-4856 16 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Atopic Dermatitis
Psoriasis
Asthma
Single Nucleotide Polymorphism
104 Citations (Scopus)

High-density genotyping study identifies four new susceptibility loci for atopic dermatitis

Ellinghaus, D., Baurecht, H., Esparza-Gordillo, J., Rodríguez, E., Matanovic, A., Marenholz, I., Hübner, N., Schaarschmidt, H., Novak, N., Michel, S., Maintz, L., Werfel, T., Meyer-Hoffert, U., Hotze, M., Prokisch, H., Heim, K., Herder, C., Hirota, T., Tamari, M., Kubo, M. & 29 others, Takahashi, A., Nakamura, Y., Tsoi, L. C., Stuart, P., Elder, J. T., Sun, L., Zuo, X., Yang, S., Zhang, X., Hoffmann, P., Nöthen, M. M., Fölster-Holst, R., Winkelmann, J., Illig, T., Boehm, B. O., Duerr, R. H., Büning, C., Brand, S., Glas, J., McAleer, M. A., Fahy, C. M., Kabesch, M., Brown, S., McLean, W. H. I., Irvine, A. D., Schreiber, S., Lee, Y-A., Franke, A. & Weidinger, S., Jul 2013, In : Nature Genetics. 45, 7, p. 808-812 5 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Keratinocytes
Ireland
Skin Diseases
Germany
3 Citations (Scopus)

The pharmacogenetics of body odor: as easy as ABCC?

Brown, S., Jul 2013, In : Journal of Investigative Dermatology. 133, 7, p. 1709-1711 3 p.

Research output: Contribution to journalArticle

Deodorants
Pharmacogenetics
Odors
Phenotype
Polymorphism
72 Citations (Scopus)

Tmem79/Matt is the matted mouse gene and is a predisposing gene for atopic dermatitis in human subjects

Saunders, S. P., Goh, C. S. M., Brown, S. J., Palmer, C. N. A., Porter, R. M., Cole, C., Campbell, L. E., Gierlinski, M., Barton, G. J., Schneider, G., Balmain, A., Prescott, A. R., Weidinger, S., Baurecht, H., Kabesch, M., Gieger, C., Lee, Y-A., Tavendale, R., Mukhopadhyay, S., Turner, S. W. & 14 others, Madhok, V. B., Sullivan, F. M., Relton, C., Burn, J., Meggitt, S., Smith, C. H., Allen, M. A., Barker, J. N. W. N., Reynolds, N. J., Cordell, H. J., Irvine, A. D., McLean, W. H. I., Sandilands, A. & Fallon, P. G., Nov 2013, In : Journal of Allergy and Clinical Immunology. 132, 5, p. 1121-1129 9 p.

Research output: Contribution to journalArticle

Atopic Dermatitis
Skin
Genes
Mutation
Single Nucleotide Polymorphism
2012
44 Citations (Scopus)

Haploinsufficiency for AAGAB causes clinically heterogeneous forms of punctate palmoplantar keratoderma

Pohler, E., Mamai, O., Hirst, J., Zamiri, M., Horn, H., Nomura, T., Irvine, A. D., Moran, B., Wilson, N. J., Smith, F. J. D., Goh, C. S. M., Sandilands, A., Cole, C., Barton, G. J., Evans, A. T., Shimizu, H., Akiyama, M., Suehiro, M., Konohana, I., Shboul, M. & 12 others, Teissier, S., Boussofara, L., Denguezli, M., Saad, A., Gribaa, M., Dopping-Hepenstal, P. J., McGrath, J. A., Brown, S. J., Goudie, D. R., Reversade, B., Munro, C. S. & McLean, W. H. I., Nov 2012, In : Nature Genetics. 44, 11, p. 1272-1276 5 p.

Research output: Contribution to journalArticle

Palmoplantar Keratoderma
Haploinsufficiency
Epidermal Growth Factor Receptor
Carrier Proteins
Vesicular Transport Adaptor Proteins
105 Citations (Scopus)
99 Downloads (Pure)

Intragenic copy number variation within filaggrin contributes to the risk of atopic dermatitis with a dose-dependent effect

Brown, S. J., Kroboth, K., Sandilands, A., Campbell, L. E., Pohler, E., Kezic, S., Cordell, H. J., McLean, W. H. I. & Irvine, A. D., Jan 2012, In : Journal of Investigative Dermatology. 132, 1, p. 98-104 7 p.

Research output: Contribution to journalArticle

Open Access
File
251 Citations (Scopus)

One remarkable molecule: filaggrin

Brown, S. J. & McLean, W. H. I., Mar 2012, In : Journal of Investigative Dermatology. 132, 3, p. 751-762 12 p.

Research output: Contribution to journalArticle

2011
252 Citations (Scopus)
116 Downloads (Pure)

Loss-of-function variants in the filaggrin gene are a significant risk factor for peanut allergy

Brown, S. J., Asai, Y., Cordell, H. J., Campbell, L. E., Zhao, Y., Liao, H., Northstone, K., Henderson, J., Alizadehfar, R., Ben-Shoshan, M., Morgan, K., Roberts, G., Masthoff, L. J. N., Pasmans, S. G. M. A., van den Akker, P. C., Wijmenga, C., Hourihane, J. OB., Palmer, C. N. A., Lack, G., Clarke, A. & 3 others, Hull, P. R., Irvine, A. D. & McLean, W. H. I., Mar 2011, In : Journal of Allergy and Clinical Immunology. 127, 3, p. 661-667 7 p.

Research output: Contribution to journalArticle

Open Access
File
77 Citations (Scopus)

Wide spectrum of filaggrin-null mutations in atopic dermatitis highlights differences between Singaporean Chinese and European populations

Chen, H., Common, J. E. A., Haines, R. L., Balakrishnan, A., Brown, S. J., Goh, C. S. M., Cordell, H. J., Sandilands, A., Campbell, L. E., Kroboth, K., Irvine, A. D., Goh, D. L. M., Tang, M. B. Y., van Bever, H. P., Giam, Y. C., McLean, W. H. I. & Lane, E. B., Jul 2011, In : British Journal of Dermatology. 165, 1, p. 106-114 9 p.

Research output: Contribution to journalArticle

2010
49 Citations (Scopus)
113 Downloads (Pure)

Chromosome 11q13.5 variant associated with childhood eczema: an effect supplementary to filaggrin mutations

O'Regan, G. M., Campbell, L. E., Cordell, H. J., Irvine, A. D., McLean, W. H. I. & Brown, S. J., Jan 2010, In : Journal of Allergy and Clinical Immunology. 125, 1, p. 170-174.e2 5 p.

Research output: Contribution to journalArticle

Open Access
File
2009
8 Citations (Scopus)

Coma blisters in 2 children on anticonvulsant medication.

Basu, A., Brown, S., Kirkham, N., Ramesh, V., Leech, S. & Devlin, A., 8 Apr 2009, In : Journal of Child Neurology. 24, 8, p. 1021-1025 5 p.

Research output: Contribution to journalArticle

Blister
Coma
Anticonvulsants
Eccrine Glands
Sweat Glands
61 Citations (Scopus)
103 Downloads (Pure)
Open Access
File
17 Citations (Scopus)

Filaggrin loss-of-function variants are associated with atopic comorbidity in pediatric inflammatory bowel disease

Van Limbergen, J., Russell, R. K., Nimmo, E. R., Zhao, Y., Liao, H., Drummond, H. E., Davies, G., Gillett, P. M., McGrogan, P., Bisset, W. M., Mahdi, G., Wilson, D. C., Brown, S. J., McLean, W. H. I. & Satsangi, J., Oct 2009, In : Inflammatory Bowel Diseases. 15, 10, p. 1492-1498 7 p.

Research output: Contribution to journalArticle

275 Citations (Scopus)

Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease

Rodriguez, E., Baurecht, H., Herberich, E., Wagenpfeil, S., Brown, S. J., Cordell, H. J., Irvine, A. D. & Weidinger, S., Jun 2009, In : Journal of Allergy and Clinical Immunology. 123, 6, p. 1361-1370.e7 10 p.

Research output: Contribution to journalArticle

2008
56 Citations (Scopus)

Atopic eczema and the filaggrin story

Brown, S. J. & Irvine, A. D., Jun 2008, In : Seminars in Cutaneous Medicine and Surgery. 27, 2, p. 128-137 10 p.

Research output: Contribution to journalArticle

89 Citations (Scopus)

Filaggrin null mutations and childhood atopic eczema: a population-based case-control study

Brown, S. J., Relton, C. L., Liao, H., Zhao, Y., Sandilands, A., Wilson, I. J., Burn, J., Reynolds, N. J., McLean, W. H. I. & Cordell, H. J., Apr 2008, In : Journal of Allergy and Clinical Immunology. 121, 4, p. 940-946.e3 7 p.

Research output: Contribution to journalArticle

2007
6 Citations (Scopus)

Pseudoxanthoma elasticum: biopsy of clinically normal skin in the investigation of patients with angioid streaks

Brown, S., Talks, S. J., Needham, S. J. & Taylor, A. E. M., Oct 2007, In : British Journal of Dermatology. 157, 4, p. 748-751 4 p.

Research output: Contribution to journalArticle

2006
9 Citations (Scopus)

The management of skin malignancy: to what extent should we rely on clinical diagnosis?

Brown, S. J. & Lawrence, C. M., Jul 2006, In : British Journal of Dermatology. 155, 1, p. 100-103 4 p.

Research output: Contribution to journalArticle