Sarah Coulthurst

Personal profile

Education/Academic qualification

Doctor of Philosophy, University of Cambridge

Master of Natural Science at Cambridge University, University of Cambridge

Bachelor of Arts, University of Cambridge

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Projects 2012 2024

2 Finished
3 Not started
3 Active

Targeting a New Kingdom The Nature and Importance of Type VI Secretion System Mediated Anti Fungal Activity (joint with University of Newcastle, Heriot-Watt University, Hans Knoll Institute, University of Exeter)

Coulthurst, S. & Hunter, B.

Wellcome Trust

1/11/19 → 31/10/24

Project: Research

Secretion, Mode of Action and Utilisation of a New Anti-Bacterial Toxin (EASTBIO)

Coulthurst, S. & Trost, M.

Biotechnology and Biological Sciences Research Council

5/09/16 → 4/09/20

Project: Research

Deployment Consequences and Utility of Bacterial Effectors (Senior Research Fellowship)

Coulthurst, S.

Wellcome Trust

28/02/15 → 27/07/20

Project: Research

Dundee Training Programme in Integrated Molecular, Cellular and Translational Biology

Arthur, S., Coulthurst, S., Hay, R. & Muqit, M.

Project: Research

Dundee Centre for Antimicrobial Resistance

Chalmers, J., Coulthurst, S., Jefferson, E., Marwick, C., Nathwani, D. & Palmer, C.

Project: Research

Research Output 2008 2019

36 Article
2 Review article
1 Chapter (peer-reviewed)
1 Meeting abstract
1 More
- 1 Editorial

1 Citation (Scopus)

22 Downloads (Pure)

A family of Type VI secretion system effector proteins that form ion-selective pores

Mariano, G., Trunk, K., Williams, D. J., Monlezun, L., Strahl, H., Pitt, S. J. & Coulthurst, S., 2 Dec 2019, In : Nature Communications. 10, 1, p. 1-15 15 p., 5484.

Research output: Contribution to journal › Article

Open Access

File

effectors

secretions

Genes

Ions

proteins

1 Citation (Scopus)

64 Downloads (Pure)

A New Front in Microbial Warfare—Delivery of Antifungal Effectors by the Type VI Secretion System

Trunk, K., Coulthurst, S. & Quinn, J., Jun 2019, In : Journal of Fungi. 5, 2, p. 1-13 13 p., 50.

Research output: Contribution to journal › Review article

Open Access

File

Weapons

Fungi

Microbiota

Autophagy

Gram-Negative Bacteria

1 Citation (Scopus)

The plant pathogen Pectobacterium atrosepticum contains a functional formate hydrogenlyase-2 complex

Finney, A. J., Lowden, R., Fleszar, M., Albareda, M., Coulthurst, S. J. & Sargent, F., 17 Aug 2019, In : Molecular Microbiology. 27 p.

Research output: Contribution to journal › Article

Pectobacterium

Hydrogen

formic acid

Genes

Formate Dehydrogenases

10 Citations (Scopus)

139 Downloads (Pure)

The Type VI secretion system: a versatile bacterial weapon

Coulthurst, S., 1 May 2019, In : Microbiology. 165, 5, p. 503-515 13 p., 000789.

Research output: Contribution to journal › Review article

Open Access

File

Weapons

Protein Array Analysis

Eukaryotic Cells

Gram-Negative Bacteria

Proteins

6 Citations (Scopus)

117 Downloads (Pure)

Dual Role for DsbA in Attacking and Targeted Bacterial Cells during Type VI Secretion System-Mediated Competition

Mariano, G., Monlezun, L. & Coulthurst, S. J., 16 Jan 2018, In : Cell Reports. 22, 3, p. 774-785 12 p.

Research output: Contribution to journal › Article

Open Access

File

Proteins

Disulfides

Serratia marcescens

Poisons

Pathogens