Virdee, Satpal

Research Output

Research Output per year

2010 2020

• 18 Article
• 1 Review article

Research Output per year

Research Output per year

Search results

• 2020

  Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases

  Mathur, S., Fletcher, A. J., Branigan, E., Hay, R. T. & Virdee, S., 16 Jan 2020, In : Cell Chemical Biology. 27, 1, p. 74-82.e6 16 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Ubiquitin-Protein Ligases
  • Ubiquitin
  • Enzymes
  • Chemical activation
  • Ubiquitin-Conjugating Enzymes
  3 Citations (Scopus)

  113 Downloads (Pure)

• Structural basis for RING-Cys-Relay E3 ligase activity and its role in axon integrity

  Mabbitt, P. D., Loreto, A., Déry, M-A., Fletcher, A. J., Stanley, M., Pao, K-C., Wood, N. T., Coleman, M. P. & Virdee, S., 1 Nov 2020, In : Nature Chemical Biology. 16, 11, p. 1227-1236 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Ubiquitin-Protein Ligases
  • Axons
  • Esterification
  • Cysteine
  • Maintenance
  1 Citation (Scopus)
• 2018

  Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity

  Pao, K-C., Wood, N. T., Knebel, A., Rafie, K., Stanley, M., Mabbitt, P. D., Sundaramoorthy, R., Hofmann, K., van Aalten, D. M. F. & Virdee, S., 11 Apr 2018, In : Nature. 556, 7701, p. 381-385 5 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Esterification
  • Ubiquitin-Protein Ligases
  • Ubiquitination
  • Genes
  • Cysteine
  48 Citations (Scopus)

  415 Downloads (Pure)

• Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

  Kwasna, D., Rehman, S. A. A., Natarajan, J., Matthews, S., Madden, R., De Cesare, V., Weidlich, S., Virdee, S., Ahel, I., Gibbs-Seymour, I. & Kulathu, Y., 5 Apr 2018, In : Molecular Cell. 70, 1, p. 150-164.e6 15 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Deubiquitinating Enzymes
  • Genomic Instability
  • Polyubiquitin
  • DNA Damage
  • Catalysis
  49 Citations (Scopus)

  174 Downloads (Pure)
• 2017

  2016 EMBO Chemical Biology Conference

  Virdee, S., 3 Jan 2017, In : ChemBioChem. 18, 1, p. 66-71 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Molecular biology
  • Congresses
  • Molecular Biology
  • Posters
  • Biological Science Disciplines
  195 Downloads (Pure)
• 2016

  Chemical Ubiquitination for Decrypting a Cellular Code

  Stanley, M. & Virdee, S., 11 May 2016, In : Biochemical Journal. 473, 10, p. 1297-1314 18 p.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  File

  • Polyubiquitin
  • Ubiquitination
  • Ubiquitin
  • Substrates
  • Deubiquitinating Enzymes
  5 Citations (Scopus)

  169 Downloads (Pure)

• Genetically directed production of recombinant, isosteric and non-hydrolyzable ubiquitin conjugates

  Stanley, M. & Virdee, S., 27 Jun 2016, In : ChemBioChem. 17, 15, p. 1472-1480 9 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • Deubiquitinating Enzymes
  • Ubiquitin
  • Methanosarcina barkeri
  • Polyubiquitin
  • Amino Acyl-tRNA Synthetases
  8 Citations (Scopus)

  89 Downloads (Pure)

• ICBS & ECBS Chemical Biology Meeting 2015 - Let them come to Berlin!

  Komatsu, T. & Virdee, S., 20 May 2016, In : ACS Chemical Biology. 11, 5, p. 1159-1166 8 p.

  Research output: Contribution to journal › Article

  Open Access

  File
  2 Citations (Scopus)

  120 Downloads (Pure)

• Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

  Pao, K. C., Stanley, M., Han, C., Lai, Y. C., Murphy, P., Balk, K., Wood, N. T., Corti, O., Corvol, J. C., Muqit, M. M. K. & Virdee, S., May 2016, In : Nature Chemical Biology. 12, 5, p. 324-331 8 p.

  Research output: Contribution to journal › Article › peer-review

  • Ubiquitin-Protein Ligases
  • Dissection
  • Parkinson Disease
  • Ubiquitin-Conjugating Enzymes
  • Phosphorylation
  52 Citations (Scopus)
• 2015

  A versatile strategy for the semisynthetic production of Ser65 phosphorylated ubiquitin and its biochemical and structural characterisation

  Han, C., Pao, K-C., Kazlauskaite, A., Muqit, M. M. K. & Virdee, S., 27 Jul 2015, In : ChemBioChem. 16, 11, p. 1574-1579 6 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ubiquitin
  • Phosphorylation
  • Disulfides
  • Crystals
  • Ubiquitin-Protein Ligases
  5 Citations (Scopus)

• Orthogonal thiol functionalization at a single atomic center for profiling transthiolation activity of E1 activating enzymes

  Stanley, M., Han, C., Knebel, A., Murphy, P., Shpiro, N. & Virdee, S., 19 Jun 2015, In : ACS Chemical Biology. 10, 6, p. 1542-1554 13 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Sulfhydryl Compounds
  • Cysteine
  • Enzymes
  • Ubiquitins
  • Oxidation-Reduction
  15 Citations (Scopus)

• Ubiquitin-C-terminal hydrolases cleave isopeptide and peptide-linked ubiquitin from structured proteins but do not edit ubiquitin homopolymers

  Bett, J. S., Ritorto, M. S., Ewan, R., Jaffray, E. G., Virdee, S., Chin, J. W., Knebel, A., Kurz, T., Trost, M., Tatham, M. H. & Hay, R. T., 15 Mar 2015, In : Biochemical Journal. 466, 3, p. 489-498 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Ubiquitin Thiolesterase
  • Homopolymerization
  • Ubiquitin
  • Peptides
  • Hydrolases
  20 Citations (Scopus)
• 2014

  Screening of DUB activity and specificity by MALDI-TOF mass spectrometry

  Ritorto, M. S., Ewan, R., Perez-Oliva, A. B., Knebel, A., Buhrlage, S. J., Wightman, M., Kelly, S. M., Wood, N. T., Virdee, S., Gray, N. S., Morrice, N. A., Alessi, D. R. & Trost, M., 27 Aug 2014, In : Nature Communications. 5, 11 p., 4763.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  File

  • enzyme activity
  • Ionization
  • Mass spectrometry
  • regulators
  • linkages
  144 Citations (Scopus)

  222 Downloads (Pure)
• 2012

  An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains

  Licchesi, J. D. F., Mieszczanek, J., Mevissen, T. E. T., Rutherford, T. J., Akutsu, M., Virdee, S., El Oualid, F., Chin, J. W., Ovaa, H., Bienz, M. & Komander, D., Jan 2012, In : Nature Structural & Molecular Biology. 19, 1, p. 62-U83 11 p.

  Research output: Contribution to journal › Article › peer-review
  70 Citations (Scopus)
• 2011

  Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains

  Akutsu, M., Ye, Y., Virdee, S., Chin, J. W. & Komander, D., 8 Feb 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 6, p. 2228-2233 6 p.

  Research output: Contribution to journal › Article › peer-review
  86 Citations (Scopus)

• Traceless and site-specific ubiquitination of recombinant proteins

  Virdee, S., Kapadnis, P. B., Elliott, T., Lang, K., Madrzak, J., Nguyen, D. P., Riechmann, L. & Chin, J. W., 20 Jul 2011, In : Journal of the American Chemical Society. 133, 28, p. 10708-10711 4 p.

  Research output: Contribution to journal › Article › peer-review
  116 Citations (Scopus)
• 2010

  Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase

  Virdee, S., Ye, Y., Nguyen, D. P., Komander, D. & Chin, J. W., Oct 2010, In : Nature Chemical Biology. 6, 10, p. 750-757 8 p.

  Research output: Contribution to journal › Article › peer-review
  215 Citations (Scopus)

• Genetically directing epsilon-N, N-dimethyl-L-lysine in recombinant histones

  Nguyen, D. P., Alai, M. M. G., Virdee, S. & Chin, J. W., 29 Oct 2010, In : Chemistry & Biology. 17, 10, p. 1072-1076 5 p.

  Research output: Contribution to journal › Article › peer-review
  65 Citations (Scopus)

• Semisynthetic Src SH2 domains demonstrate altered phosphopeptide specificity induced by incorporation of unnatural lysine derivatives

  Virdee, S., Macmillan, D. & Waksman, G., 26 Mar 2010, In : Chemistry & Biology. 17, 3, p. 274-284 11 p.

  Research output: Contribution to journal › Article › peer-review
  13 Citations (Scopus)