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Arthur, Simon

Professor

 https://orcid.org/0000-0002-8135-1958
1987 …2023
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Personal profile

Education/Academic qualification

Doctor of Philosophy, University of Oxford

Bachelor of Science, Durham University

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  • 9 Similar Profiles
Phosphotransferases Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Mitogens Medicine & Life Sciences
Macrophages Medicine & Life Sciences
p38 Mitogen-Activated Protein Kinases Medicine & Life Sciences
Interleukin-10 Medicine & Life Sciences
Calpain Medicine & Life Sciences
Mitogen-Activated Protein Kinases Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2023

Defining the Oxidative Stress-Related Mechanisms by which Activation of the Transcription Factor Nrf2 Arrests and Resolves Liver Fibrosis

Arthur, S., Dillon, J., Dinkova-Kostova, A., Hayes, J. & Henderson, C.

Medical Research Council

1/01/20 → 31/12/23

Project: Research

Elucidation of Mechanisms that Restrict Activation of the Innate Immune System to Prevent Inflammatory and Autoimmune Diseases

Arthur, S. & Cohen, P.

Medical Research Council

1/04/18 → 31/03/23

Project: Research

The Role of HMBS Phosphorylation in Acute Intermittent Porphyria

Arthur, S., Ibbotson, S. & McGuire, V.

1/03/18 → 29/02/20

Project: Research

Role of Salt Inducible Kinases in Autoimmunity

Arthur, S. & Cohen, P.

1/04/17 → 31/03/20

Project: Research

Understanding the Regulation of Leukotriene Synthesis by Mast Cells (Vacation Scholarship)

Arthur, S.

Project: Research

Research Output 1987 2019

Distinct signals and immune cells drive liver pathology and glomerulonephritis in ABIN1[D485N] mice

Nanda, S. K., Petrova, T., Marchesi, F., Gierlinski, M., Razsolkov, M., Lee, K. L., Wright, S. W., Rao, V. R., Cohen, P. & Arthur, J. S. C., 1 Dec 2019, In : Life Science Alliance. 2, 6, p. 1-19 19 p., e201900533.

Research output: Contribution to journal › Article

Open Access
File
glomerulonephritis
Pathology
pathology
Glomerulonephritis
Liver
4 Citations (Scopus)
119 Downloads (Pure)

Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus

Odqvist, L., Jevnikar, Z., Riise, R., Öberg, L., Rhedin, M., Leonard, D., Yrlid, L., Jackson, S., Mattsson, J., Nanda, S., Cohen, P., Knebel, A., Arthur, S., Thörn, K., Svenungsson, E., Jönsen, A., Gunnarsson, I., Tandre, K., Alexsson, A., Kastbom, A. & 10 others, Rantapää-Dahlqvist, S., Eloranta, M-L., Syvänen, A-C., Bengtsson, A., Johansson, P., Sandling, J. K., Sjöwall, C., Rönnblom, L., Collins, B. & Vaarala, O., 12 Jul 2019, In : Annals of the Rheumatic Diseases. 8 p.

Research output: Contribution to journal › Article

Open Access
File
Systemic Lupus Erythematosus
Polymorphism
Clustered Regularly Interspaced Short Palindromic Repeats
Genes
RNA Sequence Analysis
1 Citation (Scopus)
135 Downloads (Pure)

IL-33 regulates cytokine production and neutrophil recruitment via the p38 MAPK-activated kinases MK2/3

McCarthy, P. C., Phair, I. R., Greger, C., Pardali, K., McGuire, V. A., Clark, A. R., Gaestel, M. & Arthur, J. S. C., 17 Jan 2019, In : Immunology and Cell Biology. 97, 1, p. 54-71 18 p.

Research output: Contribution to journal › Article

Open Access
File
Neutrophil Infiltration
Mitogen-Activated Protein Kinase Kinases
p38 Mitogen-Activated Protein Kinases
Mast Cells
Cytokines
1 Citation (Scopus)
50 Downloads (Pure)

The E3 ligase HOIL-1 catalyses ester bond formation between ubiquitin and components of the Myddosome in mammalian cells

Kelsall, I., Zhang, R., Knebel, A., Arthur, S. & Cohen, P., 2 Jul 2019, In : Proceedings of the National Academy of Sciences. 116, 27, p. 13293-13298 6 p.

Research output: Contribution to journal › Article

Open Access
File
Ubiquitin-Protein Ligases
Ubiquitin
Esters
Ubiquitin C
Macrophages
3 Citations (Scopus)

ABIN2 Function Is Required To Suppress DSS-Induced Colitis by a Tpl2-Independent Mechanism

Nanda, S. K., Nagamori, T., Windheim, M., Amu, S., Aviello, G., Patterson-Kane, J., Arthur, J. S. C., Ley, S. C., Fallon, P. & Cohen, P., 1 Dec 2018, In : Journal of Immunology. 201, 11, p. 3373-3382 10 p.

Research output: Contribution to journal › Article

Colitis
Neoplasms
Myofibroblasts
Cyclooxygenase 2
Ubiquitin

Press / Media

Research reveals how immune cells can be altered to help fight inflammatory diseases

Kristopher Clark, Kirsty MacKenzie, Mark Peggie, Lorna Plater, Patrick G. A. Pedrioli, J. Simon C. Arthur & Philip Cohen

11/10/12

1 item of Media coverage

Press/Media: Research

Thesis

Investigating the role of MyD88 signalling pathway in immune mediated diseases

Author: Petrova, T., 2019

Supervisor: Arthur, J. S. (Supervisor)

Student thesis: Doctoral Thesis › Doctor of Philosophy

Regulation of cytokine and chemokine production in macrophages

Author: Pattison, M. J., 2014

Supervisor: Arthur, J. (Supervisor)

Student thesis: Doctoral Thesis › Doctor of Philosophy

File

Regulation of MyD88 signalling by MAPK activated kinases

Author: McCarthy, P. C., 2015

Supervisor: Arthur, J. (Supervisor)

Student thesis: Doctoral Thesis › Doctor of Philosophy

The innate response to fungal infection

Author: Elcombe, S. E., 2013

Supervisor: Arthur, J. (Supervisor)

Student thesis: Doctoral Thesis › Doctor of Philosophy

File