Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Dive into the research topics where Simon Hawley is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand
Hawley, S. A., Russell, F. M. & Hardie, D. G. (Lead / Corresponding author), Apr 2024, In: Biochemical Journal. 481, 8, p. 587-599 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)111 Downloads (Pure) -
BAY-3827 and SBI-0206965: potent AMPK inhibitors that paradoxically increase Thr172 phosphorylation
Hawley, S. A., Russell, F. M., Ross, F. A. & Hardie, D. G. (Lead / Corresponding author), 1 Jan 2024, In: International Journal of Molecular Sciences. 25, 1, 21 p., 453.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)183 Downloads (Pure) -
Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers
Ross, F. A., Hawley, S. A., Russell, F. M., Goodman, N. & Hardie, D. G. (Lead / Corresponding author), 1 Dec 2023, In: Biochemical Journal. 480, 23, p. 1951-1968 18 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)109 Downloads (Pure) -
Caspase cleavage and nuclear retention of the energy sensor AMPK-α1 during apoptosis
Cheratta, A. R., Thayyullathil, F., Hawley, S. A., Ross, F. A., Atrih, A., Lamont, D. J., Pallichankandy, S., Subburayan, K., Alakkal, A., Rezgui, R., Gray, A., Hardie, D. G. & Galadari, S. (Lead / Corresponding author), 3 May 2022, In: Cell Reports. 39, 5, 18 p., 110761.Research output: Contribution to journal › Article › peer-review
Open AccessFile25 Citations (Scopus)369 Downloads (Pure) -
Aldolase is a sensor for both low and high glucose, linking to AMPK and mTORC1
Li, M., Zhang, C. S., Feng, J. W., Wei, X., Zhang, C., Xie, C., Wu, Y., Hawley, S. A., Atrih, A., Lamont, D. J., Wang, Z., Piao, H. L., Hardie, D. G. & Lin, S. C. (Lead / Corresponding author), Apr 2021, In: Cell Research. 31, p. 478-481 4 p.Research output: Contribution to journal › Letter › peer-review
Open AccessFile58 Citations (Scopus)250 Downloads (Pure)