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Hadad, Sirwan


  • 229 Citations
  • 4 h-Index
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Fingerprint Dive into the research topics where Sirwan Hadad is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 4 Similar Profiles
Breast Neoplasms Medicine & Life Sciences
Endoplasmic Reticulum-Associated Degradation Medicine & Life Sciences
Metformin Medicine & Life Sciences
Phosphatidylinositol 3-Kinases Medicine & Life Sciences
Estrogen Receptors Medicine & Life Sciences
Immunity Medicine & Life Sciences
Biomarkers Medicine & Life Sciences
Neoplasms Medicine & Life Sciences

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Research Output 2008 2018

  • 229 Citations
  • 4 h-Index
  • 3 Article
  • 1 Letter
  • 1 Review article
41 Citations (Scopus)

Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1

Cha, J-H., Yang, W-H., Xia, W., Wei, Y., Chan, L-C., Lim, S-O., Li, C-W., Kim, T., Chang, S-S., Lee, H-H., Hsu, J. L., Wang, H-L., Kuo, C-W., Chang, W-C., Hadad, S., Purdie, C. A., McCoy, A. M., Cai, S., Tu, Y., Litton, J. K. & 8 others, Mittendorf, E. A., Moulder, S. L., Symmans, W. F., Thompson, A. M., Piwnica-Worms, H., Chen, C-H., Khoo, K-H. & Hung, M-C., 16 Aug 2018, In : Molecular Cell. 71, 4, p. 606-620.e7 15 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum-Associated Degradation
Cytotoxic T-Lymphocytes
4 Citations (Scopus)
90 Downloads (Pure)

A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer

Hadad, S. M., Jordan, L. B., Roy, P. G., Purdie, C. A., Iwamoto, T., Pusztai, L., Moulder-Thompson, S. L. & Thompson, A. M., 22 Sep 2016, In : BMC Cancer. 16, p. 1-11 11 p., 745.

Research output: Contribution to journalArticle

Open Access
Breast Neoplasms
Gene Expression
36 Citations (Scopus)
110 Downloads (Pure)

Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer

Schmid, P., Pinder, S. E., Wheatley, D., Macaskill, J., Zammit, C., Hu, J., Price, R., Bundred, N., Hadad, S., Shia, A., Sarker, S. J., Lim, L., Gazinska, P., Woodman, N., Korbie, D., Trau, M., Mainwaring, P., Gendreau, S., Lackner, M. R., Derynck, M. & 6 others, Wilson, T. R., Butler, H., Earl, G., Parker, P., Purushotham, A. & Thompson, A., 10 Jun 2016, In : Journal of Clinical Oncology. 34, 17, p. 1987-1994 8 p.

Research output: Contribution to journalArticle

Open Access
Phosphatidylinositol 3-Kinases
Estrogen Receptors
Breast Neoplasms
24 Citations (Scopus)

Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ER alpha negative MDA-MB-435 breast cancer model

Hadad, S. M., Appleyard, V. & Thompson, A. M., Mar 2009, In : Breast Cancer Research and Treatment. 114, 2, p. 391-391 1 p.

Research output: Contribution to journalLetter

124 Citations (Scopus)

Targeting AMPK: A new therapeutic opportunity in breast cancer

Hadad, S. M., Fleming, S. & Thompson, A. M., Jul 2008, In : Critical Reviews in Oncology/Hematology. 67, 1, p. 17 7 p.

Research output: Contribution to journalReview article