Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Dive into the research topics where Sirwan Hadad is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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Evaluating progesterone receptor agonist megestrol plus letrozole for women with early-stage estrogen-receptor-positive breast cancer: the window-of-opportunity, randomized, phase 2b, PIONEER trial
Burrell, R. A., Kumar, S., Provenzano, E., Pike, C., Dayimu, A., McIntosh, S. A., Pitsinis, V., King, P., Elsberger, B., Govindarajulu, S., Satherley, L., Hadad, S., Schmid, P., Agrawal, A., Akpuluma, B., Bell, S., Benson, J. R., Caldas, C., Cheeseman, D. & Chernukhin, I. & 8 others, , 5 Jan 2026, In: Nature Cancer. 7, 1, p. 194-206 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Downloads (Pure) -
Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
Cha, J.-H., Yang, W.-H., Xia, W., Wei, Y., Chan, L.-C., Lim, S.-O., Li, C.-W., Kim, T., Chang, S.-S., Lee, H.-H., Hsu, J. L., Wang, H.-L., Kuo, C.-W., Chang, W.-C., Hadad, S., Purdie, C. A., McCoy, A. M., Cai, S., Tu, Y. & Litton, J. K. & 8 others, , 16 Aug 2018, In: Molecular Cell. 71, 4, p. 606-620.e7 15 p.Research output: Contribution to journal › Article › peer-review
674 Link opens in a new tab Citations (Scopus) -
A prospective comparison of ER, PR, Ki67 and gene expression in paired sequential core biopsies of primary, untreated breast cancer
Hadad, S. M., Jordan, L. B., Roy, P. G., Purdie, C. A., Iwamoto, T., Pusztai, L., Moulder-Thompson, S. L. & Thompson, A. M. (Lead / Corresponding author), 22 Sept 2016, In: BMC Cancer. 16, p. 1-11 11 p., 745.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Link opens in a new tab Citations (Scopus)315 Downloads (Pure) -
Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer
Schmid, P. (Lead / Corresponding author), Pinder, S. E., Wheatley, D., Macaskill, J., Zammit, C., Hu, J., Price, R., Bundred, N., Hadad, S., Shia, A., Sarker, S. J., Lim, L., Gazinska, P., Woodman, N., Korbie, D., Trau, M., Mainwaring, P., Gendreau, S., Lackner, M. R. & Derynck, M. & 6 others, , 10 Jun 2016, In: Journal of Clinical Oncology. 34, 17, p. 1987-1994 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile85 Link opens in a new tab Citations (Scopus)318 Downloads (Pure) -
Therapeutic metformin/AMPK activation promotes the angiogenic phenotype in the ER alpha negative MDA-MB-435 breast cancer model
Hadad, S. M., Appleyard, V. & Thompson, A. M., Mar 2009, In: Breast Cancer Research and Treatment. 114, 2, p. 391-391 1 p.Research output: Contribution to journal › Letter › peer-review
27 Link opens in a new tab Citations (Scopus)