Projects per year
Personal profile
Biography
Sourav Banerjee finished his Masters from the University of Glasgow in 2009 and carried out his PhD in Life Sciences from the MRC Protein Phosphorylatyion and Ubiquitylation Unit, University of Dundee under Prof Dario Alessi in 2013. As a PhD student, his work was investigating the regulation, function, and molecular mechanism of action of AMPK-related NUAK1 kinase. Following this, he moved to University of California San Diego, USA to join the laboratory of Prof. Jack E Dixon as a postdoctoral fellow from 2014 to 2020. During that time his research was focused on the role of DYRK2 as a kinase phosphoryating and regulating the 26S proteasome. As a post doctoral scholar, he set up a multi-disciplinary project to identify and characterise a small molecule inhibitor of DYRK2 which showed efficacy in targeting multiple myeloma and triple-negative breast cancer in vivo. In March 2020 he moved to Dundee where he started as a principal investigator and a Ninewells Cancer Campaign Fellow focussing on role of novel kinases in Glioblastoma multiforme.
Research interests
Glioblastoma multiforme of Stage IV glioma has very poor 5 year survival with very limited prognosis. My current research interest is focussed on the role of extracellular post-translational modifications in regulating Glioblastoma multiforme progression. Multiple extracellular substrates like growth factors, interleukins and cytokines are highly overexpressed and phosphorylated during the progression of glioma malignancy. My laboratory will focus on elucidating the oncogenic role(s) of those extracellular phosphorylations and identify novel predictive and prognostic biomarkers for glioblastoma.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Post doctoral associate, University of California at San Diego
10 Jul 2014 → 29 Feb 2020
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Collaborations and top research areas from the last five years
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CNSLive: The Live Brain TumourCollection Programme Of Tayside
Banerjee, S. (Investigator) & King, S. (Investigator)
1/03/24 → 28/02/26
Project: Research
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Establishing A Pleiotropic Brain-Penetrant Small-Molecule To Impede Glioblastoma (Joint with University of Arizona)
Banerjee, S. (Investigator)
15/02/24 → 14/11/24
Project: Research
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A Single Kinase Modulates The Diverse Extracellular Phosphoproteome Of Glioblastoma Multiforme
Banerjee, S. (Investigator)
1/08/22 → 31/07/26
Project: Research
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Exploiting Synthetic Lethality For The Treatment Of Glioma (PhD Sudentship)
Banerjee, S. (Investigator) & Dinkova-Kostova, A. (Investigator)
Project: Research
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Ultra-High Definition Imaging - MRC Equipment Grant
Alessi, D. (Investigator), Banerjee, S. (Investigator), Cantley, J. (Investigator), Corner, G. (Investigator), Hayes, J. (Investigator), Hoskins, P. (Investigator), Kang, L. (Investigator), McNeilly, A. (Investigator), McSorley, H. (Investigator), Murdoch, C. (Investigator) & Rena, G. (Investigator)
1/11/22 → 31/03/23
Project: Research
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A green bio-organic catalyst (taurine) promoted one-pot synthesis of (R/S)-2-thioxo-3,4-dihydropyrimidine(TDHPM)-5-carboxanilides: chiral investigations using circular dichroism and validation by computational approaches
Parmar, M. P., Vala, D. P., Bhalodiya, S. S., Upadhyay, D. B., Patel, C. D., Patel, S. G., Gandholi, S. R., Shaik, A. H., Dunne Miller, A., Nogales, J., Banerjee, S., Padrón, J. M., Amri, N., Kandukuri, N. K. & Patel, H. M. (Lead / Corresponding author), 19 Mar 2024, In: RSC Advances. 14, 13, p. 9300-9313 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Citations (Scopus)84 Downloads (Pure) -
AI is a Viable Alternative to High Throughput Screening: a 318-Target Study
2 Apr 2024, In: Scientific Reports. 14, 16 p., 7526.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)70 Downloads (Pure) -
Alkoxy-functionalised dihydropyrimido[4,5-b]quinolinones enabling anti-proliferative and anti-invasive agents
Patel, S. G., Sharma, I., Parmar, M. P., Nogales, J., Patel, C. D., Bhalodiya, S. S., Vala, D. P., Shah, N. V., Banerjee, S. (Lead / Corresponding author) & Patel, H. M. (Lead / Corresponding author), 20 Jun 2024, In: Chemical Communications. 55, p. 7093-7096 4 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Click-chemistry mediated synthesis of OTBN-1,2,3-Triazole derivatives exhibiting STK33 inhibition with diverse anti-cancer activities
Vala, D. P., Dunne Miller, A., Atmasidha, A., Parmar, M. P., Patel, C. D., Upadhyay, D. B., Bhalodiya, S. S., González-Bakker, A., Khan, A. N., Nogales, J., Padrón, J. M., Banerjee, S. (Lead / Corresponding author) & Patel, H. M. (Lead / Corresponding author), Aug 2024, In: Bioorganic chemistry. 149, 11 p., 107485.Research output: Contribution to journal › Article › peer-review
Open AccessFile37 Downloads (Pure) -
Indole clubbed 2,4-thiazolidinedione linked 1,2,3-triazole as a potent antimalarial and antibacterial agent against drug-resistant strain and molecular modeling studies
Upadhyay, D. B., Mokariya, J. A., Patel, P. J., Patel, S. G., Das, A., Nandi, A., Nogales, J., More, N., Kumar, A., Rajani, D. P., Narayan, M., Kumar, J., Banerjee, S., Sahoo, S. K. & Patel, H. M. (Lead / Corresponding author), Apr 2024, In: Archiv der Pharmazie. 357, 4, 20 p., 2300673.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus)
Prizes
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Student led Award for most Innovative and Inspirational Teaching
Banerjee, S. (Recipient), 19 Apr 2024
Prize: Prize (including medals and awards)
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Activities
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Novel kinases in cancer
Banerjee, S. (Speaker)
20 Mar 2024Activity: Talk or presentation types › Invited talk
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First-in-class brain-penetrant pleiotropic small molecule targets proliferation and stemness of glioma
Banerjee, S. (Speaker), Tandon, V. (Contributor), Ferro, F. (Contributor), Nogales, J. (Contributor), Sharma, I. (Contributor) & Dunne Miller, A. (Contributor)
13 Feb 2024Activity: Talk or presentation types › Oral presentation
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Development of a kinase inhibitor for triple-negative breast cancer therapy
Banerjee, S. (Speaker)
17 Jan 2023Activity: Talk or presentation types › Invited talk
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BBSRC Fellows' Conference 2023
Banerjee, S. (Participant)
28 Jun 2023Activity: Participating in or organising an event types › Participation in conference
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Rationally designed small-molecule impedes triple-negative breast cancer progression
Banerjee, S. (Speaker)
8 Jun 2023Activity: Talk or presentation types › Keynote
Press/Media
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Indole clubbed 2,4-thiazolidinedione linked 1,2,3-triazole as a potent antimalarial and antibacterial agent against drug-resistant strain and molecular modeling studies
Banerjee, S. & Nogales, J.
25/01/24
1 item of Media coverage
Press/Media: Other
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University of Dundee Honours Indian Researcher with a Fellowship in 2022
26/06/22
1 item of Media coverage
Press/Media: Other
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Indian Researcher Wins Fellowship At University Of Dundee
22/06/22
1 item of Media coverage
Press/Media: Other
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Prestigious Fellowship awarded to Dundee researcher
16/06/22
1 item of Media coverage
Press/Media: Other