Projects per year
Personal profile
Biography
Sourav Banerjee finished his Masters from the University of Glasgow in 2009 and carried out his PhD in Life Sciences from the MRC Protein Phosphorylatyion and Ubiquitylation Unit, University of Dundee under Prof Dario Alessi in 2013. As a PhD student, his work was investigating the regulation, function, and molecular mechanism of action of AMPK-related NUAK1 kinase. Following this, he moved to University of California San Diego, USA to join the laboratory of Prof. Jack E Dixon as a postdoctoral fellow from 2014 to 2020. During that time his research was focused on the role of DYRK2 as a kinase phosphoryating and regulating the 26S proteasome. As a post doctoral scholar, he set up a multi-disciplinary project to identify and characterise a small molecule inhibitor of DYRK2 which showed efficacy in targeting multiple myeloma and triple-negative breast cancer in vivo. In March 2020 he moved to Dundee where he started as a principal investigator and a Ninewells Cancer Campaign Fellow focussing on role of novel kinases in Glioblastoma multiforme.
Research interests
Glioblastoma multiforme of Stage IV glioma has very poor 5 year survival with very limited prognosis. My current research interest is focussed on the role of extracellular post-translational modifications in regulating Glioblastoma multiforme progression. Multiple extracellular substrates like growth factors, interleukins and cytokines are highly overexpressed and phosphorylated during the progression of glioma malignancy. My laboratory will focus on elucidating the oncogenic role(s) of those extracellular phosphorylations and identify novel predictive and prognostic biomarkers for glioblastoma.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Post doctoral associate, University of California at San Diego
10 Jul 2014 → 29 Feb 2020
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Network
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Ultra-High Definition Imaging - MRC Equipment Grant
Alessi, D., Banerjee, S., Cantley, J., Corner, G., Hayes, J., Hoskins, P., Kang, L., McNeilly, A., McSorley, H., Murdoch, C. & Rena, G.
1/11/22 → 31/03/23
Project: Research
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A Single Kinase Modulates The Diverse Extracellular Phosphoproteome Of Glioblastoma Multiforme
1/08/22 → 31/07/26
Project: Research
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Secretory Pathway Phosphorylation Regulates Proglucagon Processing
1/11/21 → 31/12/22
Project: Research
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Secreted Phosphoproteme In Blood As Early Detection And Risk Stratification Biomarkers Of Glioma
1/09/21 → 31/08/22
Project: Research
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Dual inhibition of HSF1 and DYRK2 impedes cancer progression
Tandon, V., Moreno, R., Allmeroth, K., Quinn, J., Wiley, S. E., Nicely, L. G., Denzel, M. S., Edwards, J., de la Vega, L. & Banerjee, S., Jan 2023, In: Bioscience Reports. 43, 1, 14 p., BSR20222102.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Downloads (Pure) -
One-pot two-step catalytic synthesis of 6-amino-2-pyridone-3,5-dicarbonitriles enabling anti-cancer bioactivity
Nicely, L. G., Vala, R. M., Upadhyay, D. B., Nogales, J., Chi, C., Banerjee, S. & Patel, H. M., 24 Aug 2022, In: RSC Advances. 12, 37, p. 23889-23897 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)13 Downloads (Pure) -
Optimising Sonodynamic Therapy for Treating Malignant Glioma
Keenlyside, A., Guy-Nicely, L., Marples, T., Hossain-Ibrahim, K., Banerjee, S. & Joseph, J., 2022, Proceedings of the Glasgow Neuro 10th Annual Conference 2022. Surgical Neurology InternationalResearch output: Chapter in Book/Report/Conference proceeding › Conference contribution
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Synthesis of N-(4-chlorophenyl) substituted pyrano[2,3-c]pyrazoles enabling PKBβ/AKT2 inhibitory and in vitro anti-glioma activity
Vala, R. M., Tandon, V., Nicely, L., Guo, L., Gu, Y., Banerjee, S. & Patel, H. M., 2022, In: Annals of Medicine. 54, 1, p. 2549-2561 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)12 Downloads (Pure) -
Syrbactin-class dual constitutive- and immuno-proteasome inhibitor TIR-199 impedes myeloma-mediated bone degeneration in vivo
Tandon, V., Vala, R. M., Chen, A., Sah, R. L., Patel, H. M., Pirrung, M. C. & Banerjee, S., 11 Feb 2022, In: Bioscience Reports. 42, 2, p. 1-13 13 p., BSR20212721.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)47 Downloads (Pure)
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Development of a brain penetrant kinase inhibitor for Glioblastoma
Sourav Banerjee (Speaker)
20 Jan 2023Activity: Talk or presentation types › Invited talk
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Cancer and how we target it
Sourav Banerjee (Speaker)
20 Jan 2023Activity: Talk or presentation types › Invited talk
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Development of a kinase inhibitor for triple-negative breast cancer therapy
Sourav Banerjee (Speaker)
17 Jan 2023Activity: Talk or presentation types › Invited talk
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Life Sciences Virtual Work Experience Week 2021
Erin Hardee (Organiser), Senga Robertson-Albertyn (Contributor), Carmen Escudero-Martinez (Contributor), Anna Sanchez Avila (Contributor), Margarida Trigo (Contributor), Christopher Henstridge (Member), Laureano de la Vega (Contributor), Sourav Banerjee (Contributor), Grant Phillips (Contributor), Kaushik Hatti (Contributor) & Naomi Shek (Contributor)
26 Jul 2021 → 30 Jul 2021Activity: Other activity types › Schools engagement
Press/Media
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University of Dundee Honours Indian Researcher with a Fellowship in 2022
26/06/22
1 item of Media coverage
Press/Media: Other
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Indian Researcher Wins Fellowship At University Of Dundee
22/06/22
1 item of Media coverage
Press/Media: Other
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Prestigious Fellowship awarded to Dundee researcher
16/06/22
1 item of Media coverage
Press/Media: Other