Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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LTQ Oritrap Velos Mass Spectrometer from Thermo-Fisher (Quantitative Proteomics for the Dundee Cancer Centre)
Clarke, P. (Investigator), Dinkova-Kostova, A. (Investigator), Hay, R. (Investigator), Hayes, J. (Investigator), Hiom, K. (Investigator) & Keyse, S. (Investigator)
Project: Research
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Regulation of the Oncogenic Potential of Signalling through the Ras/ERK Pathway by Dual-Specificity Phosphates 5 (joint with Universities of Bath and Liverpool and Beatson Institute)
Hiom, K. (Investigator) & Keyse, S. (Investigator)
1/09/16 → 30/09/20
Project: Research
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Contribution by NRF2 Upregulation to Lung Carcinogenesis and the Possible Therapeutic Value of NRF2 Inhibition by GSK-3 (Joint with Universities of St Andrews, Edinburgh and Pennsylvania)
Dinkova-Kostova, A. (Investigator), Hayes, J. (Investigator), Henderson, C. (Investigator), Keyse, S. (Investigator), Lamond, A. (Investigator) & Sutherland, C. (Investigator)
1/05/16 → 31/10/19
Project: Research
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Aref#d: 21731. Annual Equipment Allocation 2008/09
Blow, J. (Investigator), Keyse, S. (Investigator), Lane, B. (Investigator), Lane, D. (Investigator), Leigh, I. (Investigator), Nathke, I. (Investigator), Perkins, N. (Investigator) & Wolf, R. (Investigator)
1/04/05 → 31/03/13
Project: Research
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Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6
Kidger, A. M., Saville, M. K., Rushworth, L. K., Davidson, J., Stellzig, J., Ono, M., Kuebelsbeck, L. A., Janssen, K.-P., Holzmann, B., Morton, J. P., Sansom, O. J., Caunt, C. J. & Keyse, S. M. (Lead / Corresponding author), 13 May 2022, In: Oncogene. 41, 20, p. 2811-2823 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)75 Downloads (Pure) -
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy
Ferguson, B. S., Wennersten, S. A., Demos-Davies, K. M., Rubino, M., Robinson, E. L., Cavasin, M. A., Stratton, M. S., Kidger, A. M., Hu, T., Keyse, S. M., McKnight, R. A., Lane, R. H., Nozik, E. S., Weiser-Evans, M. C. M. & McKinsey, T. A. (Lead / Corresponding author), Aug 2021, In: American Journal of Physiology - Heart and Circulatory Physiology (AJP - Heart and Circulatory Physiology). 321, 2, p. H382–H389 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)96 Downloads (Pure) -
Dual-specificity MAP kinase phosphatases in health and disease
Seternes, O.-M., Kidger, A. M. & Keyse, S. (Lead / Corresponding author), 1 Jan 2019, In: BBA - Molecular Cell Research. 1866, 1, p. 124-143 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile93 Citations (Scopus)541 Downloads (Pure) -
The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy
Reader, C. S., Vallath, S., Steele, C. W., Haider, S., Brentnall, A., Desai, A., Moore, K. M., Jamieson, N. B., Chang, D., Bailey, P., Scarpa, A., Lawlor, R., Chelala, C., Keyse, S. M., Biankin, A., Morton, J. P., Evans, T. R. J., Barry, S. T., Sansom, O. J. & Kocher, H. M. & 1 others, , Nov 2019, In: Journal of Pathology. 249, 3, p. 332-342 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile72 Citations (Scopus)207 Downloads (Pure) -
Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling
Kidger, A. M., Rushworth, L. K., Stellzig, J., Davidson, J., Bryant, C. J., Bayley, C., Caddye, E., Rogers, T., Keyse, S. M. (Lead / Corresponding author) & Caunt, C. J. (Lead / Corresponding author), 17 Jan 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 3, p. E317-E326 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile62 Citations (Scopus)242 Downloads (Pure)
Datasets
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Data from "Dual-specificity phosphatase 5 (DUSP5) controls the localized inhibition, propagation and transforming potential of ERK signaling"
Caunt, J. (Creator), Keyse, S. M. (Contributor) & Bath, U. O. (Contributor), University of Bath, 2016
DOI: 10.15125/bath-00317, http://researchdata.bath.ac.uk/id/eprint/317
Dataset