Keyse, Stephen


  • 9290 Citations
  • 45 h-Index
1983 …2020
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Fingerprint Dive into the research topics where Stephen Keyse is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 5 Similar Profiles
Phosphotransferases Medicine & Life Sciences
Dual-Specificity Phosphatases Medicine & Life Sciences
Phosphoprotein Phosphatases Medicine & Life Sciences
Mitogen-Activated Protein Kinases Medicine & Life Sciences
Mitogen-Activated Protein Kinase Phosphatases Medicine & Life Sciences
Phosphoric Monoester Hydrolases Medicine & Life Sciences
Dual Specificity Phosphatase 1 Medicine & Life Sciences
Fibroblasts Medicine & Life Sciences

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Projects 2013 2020

Research Output 1983 2019

4 Citations (Scopus)
95 Downloads (Pure)

Dual-specificity MAP kinase phosphatases in health and disease

Seternes, O-M., Kidger, A. M. & Keyse, S., 1 Jan 2019, In : BBA - Molecular Cell Research. 1866, 1, p. 124-143 20 p.

Research output: Contribution to journalArticle

Open Access
Phosphoric Monoester Hydrolases
MAP Kinase Signaling System
Genetic Models
14 Downloads (Pure)

The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy

Reader, C. S., Vallath, S., Steele, C. W., Haider, S., Brentnall, A., Desai, A., Moore, K. M., Jamieson, N. B., Chang, D., Bailey, P., Scarpa, A., Lawlor, R., Chelala, C., Keyse, S. M., Biankin, A., Morton, J. P., Evans, T. R. J., Barry, S. T., Sansom, O. J., Kocher, H. M. & 1 others, Marshall, J. F., 1 Jul 2019, In : Journal of Pathology. 11 p.

Research output: Contribution to journalArticle

Open Access
Pancreatic Neoplasms
22 Citations (Scopus)
83 Downloads (Pure)

Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling

Kidger, A. M., Rushworth, L. K., Stellzig, J., Davidson, J., Bryant, C. J., Bayley, C., Caddye, E., Rogers, T., Keyse, S. M. & Caunt, C. J., 17 Jan 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 3, p. E317-E326 10 p.

Research output: Contribution to journalArticle

Open Access
Dual-Specificity Phosphatases
Cell Proliferation
MAP Kinase Signaling System
Cell Aging
10 Citations (Scopus)
104 Downloads (Pure)

Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2

Perander, M., Al-Mahdi, R., Jensen, T. C., Nunn, J. A. L., Kildalsen, H., Johansen, B., Gabrielsen, M., Keyse, S. M. & Seternes, O-M., 2 Mar 2017, In : Scientific Reports. 7, p. 1-13 13 p., 43471.

Research output: Contribution to journalArticle

Open Access
Mitogen-Activated Protein Kinase 6
Phosphoric Monoester Hydrolases
p38 Mitogen-Activated Protein Kinases
2 Citations (Scopus)

Dual-specificity MAP kinase (MAPK) phosphatases (MKPs) and their involvement in cancer

Kidger, A. M. & Keyse, S. M., 1 Jan 2016, Protein Tyrosine Phosphatases in Cancer. Neel, B. G. & Tonks, N. K. (eds.). New York: Springer New York, p. 201-231 31 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Mitogen-Activated Protein Kinase Phosphatases
Phosphoric Monoester Hydrolases


Functional analysis of the Argonaute family proteins during early embryonic and germ cell development in the mouse

Author: Comazzetto, S., 2013

Supervisor: Keyse, S. (Supervisor) & O'Carroll, D. (External person) (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy


The Development of Photo-crosslinkable Trapping Mutants as Tools to Investigate the Interactions of Protein Tyrosine Phosphatases

Author: Pavic, K., 2013

Supervisor: Keyse, S. (Supervisor), Kohn, M. (External person) (Supervisor), Krijgsveld , J. (External person) (Supervisor) & Lemke, E. (External person) (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy


The Regulation of Oncogenic MAP Kinase Signalling by Dual-Specificity MAP Kinase Phosphatases

Author: Kidger, A. M., 2016

Supervisor: Keyse, S. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy