Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Stephen Keyse is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
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LTQ Oritrap Velos Mass Spectrometer from Thermo-Fisher (Quantitative Proteomics for the Dundee Cancer Centre)
Clarke, P. (Investigator), Dinkova-Kostova, A. (Investigator), Hay, R. (Investigator), Hayes, J. (Investigator), Hiom, K. (Investigator) & Keyse, S. (Investigator)
Project: Research
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Regulation of the Oncogenic Potential of Signalling through the Ras/ERK Pathway by Dual-Specificity Phosphates 5 (joint with Universities of Bath and Liverpool and Beatson Institute)
Hiom, K. (Investigator) & Keyse, S. (Investigator)
1/09/16 → 30/09/20
Project: Research
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Contribution by NRF2 Upregulation to Lung Carcinogenesis and the Possible Therapeutic Value of NRF2 Inhibition by GSK-3 (Joint with Universities of St Andrews, Edinburgh and Pennsylvania)
Dinkova-Kostova, A. (Investigator), Hayes, J. (Investigator), Henderson, C. (Investigator), Keyse, S. (Investigator), Lamond, A. (Investigator) & Sutherland, C. (Investigator)
1/05/16 → 31/10/19
Project: Research
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Aref#d: 21731. Annual Equipment Allocation 2008/09
Blow, J. (Investigator), Keyse, S. (Investigator), Lane, B. (Investigator), Lane, D. (Investigator), Leigh, I. (Investigator), Nathke, I. (Investigator), Perkins, N. (Investigator) & Wolf, R. (Investigator)
1/04/05 → 31/03/13
Project: Research
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Oxidative stress responses in mammalian cells
Keyse, S. M., 15 Nov 2024, Molecular Genetics of Drug Resistance. Hayes, J. D. & Wolf, C. R. (eds.). CRC Press, p. 335-372 38 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Suppression of mutant Kirsten-RAS (KRASG12D)-driven pancreatic carcinogenesis by dual-specificity MAP kinase phosphatases 5 and 6
Kidger, A. M., Saville, M. K., Rushworth, L. K., Davidson, J., Stellzig, J., Ono, M., Kuebelsbeck, L. A., Janssen, K.-P., Holzmann, B., Morton, J. P., Sansom, O. J., Caunt, C. J. & Keyse, S. M. (Lead / Corresponding author), 13 May 2022, In: Oncogene. 41, 20, p. 2811-2823 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile11 Citations (Scopus)93 Downloads (Pure) -
DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy
Ferguson, B. S., Wennersten, S. A., Demos-Davies, K. M., Rubino, M., Robinson, E. L., Cavasin, M. A., Stratton, M. S., Kidger, A. M., Hu, T., Keyse, S. M., McKnight, R. A., Lane, R. H., Nozik, E. S., Weiser-Evans, M. C. M. & McKinsey, T. A. (Lead / Corresponding author), Aug 2021, In: American Journal of Physiology - Heart and Circulatory Physiology (AJP - Heart and Circulatory Physiology). 321, 2, p. H382–H389 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)107 Downloads (Pure) -
Dual-specificity MAP kinase phosphatases in health and disease
Seternes, O.-M., Kidger, A. M. & Keyse, S. (Lead / Corresponding author), 1 Jan 2019, In: BBA - Molecular Cell Research. 1866, 1, p. 124-143 20 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile104 Citations (Scopus)578 Downloads (Pure) -
The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy
Reader, C. S., Vallath, S., Steele, C. W., Haider, S., Brentnall, A., Desai, A., Moore, K. M., Jamieson, N. B., Chang, D., Bailey, P., Scarpa, A., Lawlor, R., Chelala, C., Keyse, S. M., Biankin, A., Morton, J. P., Evans, T. R. J., Barry, S. T., Sansom, O. J. & Kocher, H. M. & 1 others, , Nov 2019, In: Journal of Pathology. 249, 3, p. 332-342 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile82 Citations (Scopus)242 Downloads (Pure)
Datasets
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Data from "Dual-specificity phosphatase 5 (DUSP5) controls the localized inhibition, propagation and transforming potential of ERK signaling"
Caunt, J. (Creator), Keyse, S. M. (Contributor) & Bath, U. O. (Contributor), University of Bath, 2016
DOI: 10.15125/bath-00317, http://researchdata.bath.ac.uk/id/eprint/317
Dataset