Projects per year
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Projects
Contribution by NRF2 Upregulation to Lung Carcinogenesis and the Possible Therapeutic Value of NRF2 Inhibition by GSK-3 (Joint with Universities of St Andrews, Edinburgh and Pennsylvania)
Dinkova-Kostova, A., Hayes, J., Henderson, C., Keyse, S., Lamond, A. & Sutherland, C.
1/05/16 → 31/10/19
Project: Research
Research Output
Dual-specificity MAP kinase phosphatases in health and disease
Seternes, O-M., Kidger, A. M. & Keyse, S., 1 Jan 2019, In : BBA - Molecular Cell Research. 1866, 1, p. 124-143 20 p.Research output: Contribution to journal › Article
Open Access
File
6
Citations
(Scopus)
158
Downloads
(Pure)
The integrin αvβ6 drives pancreatic cancer through diverse mechanisms and represents an effective target for therapy
Reader, C. S., Vallath, S., Steele, C. W., Haider, S., Brentnall, A., Desai, A., Moore, K. M., Jamieson, N. B., Chang, D., Bailey, P., Scarpa, A., Lawlor, R., Chelala, C., Keyse, S. M., Biankin, A., Morton, J. P., Evans, T. R. J., Barry, S. T., Sansom, O. J., Kocher, H. M. & 1 others, , 1 Jul 2019, In : Journal of Pathology. 11 p.Research output: Contribution to journal › Article
Open Access
File
3
Citations
(Scopus)
73
Downloads
(Pure)
Dual-specificity phosphatase 5 controls the localized inhibition, propagation, and transforming potential of ERK signaling
Kidger, A. M., Rushworth, L. K., Stellzig, J., Davidson, J., Bryant, C. J., Bayley, C., Caddye, E., Rogers, T., Keyse, S. M. & Caunt, C. J., 17 Jan 2017, In : Proceedings of the National Academy of Sciences of the United States of America. 114, 3, p. E317-E326 10 p.Research output: Contribution to journal › Article
Open Access
File
25
Citations
(Scopus)
146
Downloads
(Pure)
Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2
Perander, M., Al-Mahdi, R., Jensen, T. C., Nunn, J. A. L., Kildalsen, H., Johansen, B., Gabrielsen, M., Keyse, S. M. & Seternes, O-M., 2 Mar 2017, In : Scientific Reports. 7, p. 1-13 13 p., 43471.Research output: Contribution to journal › Article
Open Access
File
11
Citations
(Scopus)
157
Downloads
(Pure)
Dual-specificity MAP kinase (MAPK) phosphatases (MKPs) and their involvement in cancer
Kidger, A. M. & Keyse, S. M., 1 Jan 2016, Protein Tyrosine Phosphatases in Cancer. Neel, B. G. & Tonks, N. K. (eds.). New York: Springer New York, p. 201-231 31 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter
4
Citations
(Scopus)
Thesis
Functional analysis of the Argonaute family proteins during early embryonic and germ cell development in the mouse
Author: Comazzetto, S., 2013Supervisor: Keyse, S. (Supervisor) & O'Carroll, D. (External person) (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
The Development of Photo-crosslinkable Trapping Mutants as Tools to Investigate the Interactions of Protein Tyrosine Phosphatases
Author: Pavic, K., 2013Supervisor: Keyse, S. (Supervisor), Kohn, M. (External person) (Supervisor), Krijgsveld , J. (External person) (Supervisor) & Lemke, E. (External person) (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File
The Regulation of Oncogenic MAP Kinase Signalling by Dual-Specificity MAP Kinase Phosphatases
Author: Kidger, A. M., 2016Supervisor: Keyse, S. (Supervisor)
Student thesis: Doctoral Thesis › Doctor of Philosophy
File