Patterson, Stephen

Dr

  • 198 Citations
  • 5 h-Index
20142019
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Research Output 2014 2019

  • 198 Citations
  • 5 h-Index
  • 6 Article
  • 1 Review article
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Article
2019
4 Citations (Scopus)

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis

Thomas, M. G., De Rycker, M., Ajakane, M., Albrecht, S., Álvarez-Pedraglio, A. I., Boesche, M., Brand, S., Campbell, L., Cantizani-Perez, J., Cleghorn, L. A. T., Copley, R. C. B., Crouch, S. D., Daugan, A., Drewes, G., Ferrer, S., Ghidelli-Disse, S., Gonzalez, S., Gresham, S. L., Hill, A. P., Hindley, S. J. & 32 others, Lowe, R. M., MacKenzie, C. J., MacLean, L., Manthri, S., Martin, F., Miguel-Siles, J., Nguyen, V. L., Norval, S., Osuna-Cabello, M., Woodland, A., Patterson, S., Pena, I., Quesada-Campos, M. T., Reid, I. H., Revill, C., Riley, J., Ruiz-Gomez, J. R., Shishikura, Y., Simeons, F. R. C., Smith, A., Smith, V. C., Spinks, D., Stojanovski, L., Thomas, J., Thompson, S., Underwood, T., Gray, D. W., Fiandor, J. M., Gilbert, I. H., Wyatt, P. G., Read, K. D. & Miles, T. J., 14 Feb 2019, In : Journal of Medicinal Chemistry. 62, 3, p. 1180-1202 23 p.

Research output: Contribution to journalArticle

Visceral Leishmaniasis
Leishmania major
Leishmania donovani
Standard of Care
Solubility
2017
6 Citations (Scopus)
72 Downloads (Pure)
Open Access
File
Leishmania donovani
Pharmaceutical Preparations
Antimony
Sulfones
Peritoneal Macrophages
2016
25 Citations (Scopus)
76 Downloads (Pure)

Activation of bicyclic nitro-drugs by a novel nitroreductase (NTR2) in Leishmania

Wyllie, S., Roberts, A. J., Norval, S., Patterson, S., Foth, B. J., Berriman, M., Read, K. D. & Fairlamb, A. H., 3 Nov 2016, In : PLoS Pathogens. 12, 11, p. 1-22 22 p., e1005971.

Research output: Contribution to journalArticle

Open Access
File
Nitroreductases
Leishmania
Nitro Compounds
Nifurtimox
Pharmaceutical Preparations
30 Citations (Scopus)
107 Downloads (Pure)

The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis

Patterson, S., Wyllie, S., Norval, S., Stojanovski, L., Simeons, F. R. C., Auer, J. L., Osuna-Cabello, M., Read, K. D. & Fairlamb, A. H., 24 May 2016, In : eLife. 5, p. 1-21 21 p., e09744.

Research output: Contribution to journalArticle

Open Access
File
Visceral Leishmaniasis
Hormesis
Pharmaceutical Preparations
Parasites
Nitroreductases
2015
15 Citations (Scopus)
77 Downloads (Pure)

Genomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African Trypanosome

Jones, D. C., Foth, B. J., Urbaniak, M. D., Patterson, S., Ong, H. B., Berriman, M. & Fairlamb, A. H., 18 Dec 2015, In : PLoS Neglected Tropical Diseases. 9, 12, e0004299.

Research output: Contribution to journalArticle

Open Access
File
Trypanosomiasis
Proteomics
Cell Line
Trypanosoma brucei brucei
Polypharmacology
2014
115 Citations (Scopus)
108 Downloads (Pure)
Open Access
File
Pharmaceutical Preparations
Neglected Diseases
African Trypanosomiasis
Trypanosoma brucei brucei
Trypanosoma cruzi