Tauro, Sudhir

Dr

  • United Kingdom

  • 4461 Citations
  • 16 h-Index
20012019
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Research Output 2001 2019

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Article
2019
11 Citations (Scopus)
72 Downloads (Pure)

TP53 mutation status divides myelodysplastic syndromes with complex karyotypes into distinct prognostic subgroups

International Working Group for MDS Molecular Prognostic Committee, Haase, D., Stevenson, K. E., Neuberg, D., Maciejewski, J. P., Nazha, A., Sekeres, M. A., Ebert, B. L., Garcia-Manero, G., Haferlach, C., Haferlach, T., Kern, W., Ogawa, S., Nagata, Y., Yoshida, K., Graubert, T. A., Walter, M. J., List, A. F., Komrokji, R. S., Padron, E. & 31 others, Sallman, D., Papaemmanuil, E., Campbell, P. J., Savona, M. R., Seegmiller, A., Adès, L., Fenaux, P., Shih, L. Y., Bowen, D., Groves, M. J., Tauro, S., Fontenay, M., Kosmider, O., Bar-Natan, M., Steensma, D., Stone, R., Heuser, M., Thol, F., Cazzola, M., Malcovati, L., Karsan, A., Ganster, C., Hellström-Lindberg, E., Boultwood, J., Pellagatti, A., Santini, V., Quek, L., Vyas, P., Tüchler, H., Greenberg, P. L. & Bejar, R., Jul 2019, In : Leukemia. 33, 7, p. 1747-1758 12 p.

Research output: Contribution to journalArticle

Open Access
File
Myelodysplastic Syndromes
Karyotype
Mutation
Chromosome Aberrations
Critical Care
2018
1 Citation (Scopus)
105 Downloads (Pure)
Open Access
File
Myelodysplastic Syndromes
Cytogenetics
Survival
Intrinsic Factor
Acute Myeloid Leukemia
2017
7 Citations (Scopus)
118 Downloads (Pure)

Telomere length is an independent prognostic marker in MDS but not in de novo AML

Williams, J., Heppel, N. H., Britt-Compton, B., Grimstead, J. W., Jones, R. E., Tauro, S., Bowen, D. T., Knapper, S., Groves, M., Hills, R. K., Pepper, C., Baird, D. M. & Fegan, C., 11 Jul 2017, In : British Journal of Haematology. 178, 2, p. 240-249 10 p.

Research output: Contribution to journalArticle

Open Access
File
Telomere
Acute Myeloid Leukemia
Cytogenetics
Multivariate Analysis
Prospective Studies
2016
2 Citations (Scopus)
189 Downloads (Pure)

An unusual extranodal T-cell non-Hodgkin lymphoma

Coats, J. T., Mackie, A. D. R., Kernohan, N. M., Ramkumar, P. G., McMahon, L. M., Goodlad, J. R. & Tauro, S., 10 Sep 2016, In : Lancet. 388, 10049, p. 1127-1128 2 p.

Research output: Contribution to journalArticle

Open Access
File
1 Citation (Scopus)
119 Downloads (Pure)

Impact of socioeconomic status on disease phenotype, genomic landscape and outcomes in myelodysplastic syndromes

Mastaglio, F., Bedair, K., Papaemmanuil, E., Groves, M. J., Hyslop, A., Keenan, N., Hothersall, E. J., Campbell, P. J., Bowen, D. T. & Tauro, S., Jul 2016, In : British Journal of Haematology. 174, 2, p. 227-234 8 p.

Research output: Contribution to journalArticle

Open Access
File
Myelodysplastic Syndromes
Social Class
Phenotype
Survival
Refractory Anemia
46 Citations (Scopus)
86 Downloads (Pure)

Time-dependent changes in mortality and transformation risk in MDS

Pfeilstocker, M., Tuechler, H., Sanz, G., Schanz, J., Garcia-Manero, G., Solé, F., Bennett, J. M., Bowen, D., Fenaux, P., Dreyfus, F., Kantarjian, H., Kuendgen, A., Malcovati, L., Cazzola, M., Cermak, J., Levis, A., Luebbert, M., Maciejewski, J., Machherndl-Spandl, S., Magalhaes, S. M. M. & 11 others, Miyazaki, Y., Sekeres, M. A., Sperr, W. R., Stauder, R., Tauro, S., Valent, P., Vallespi, T., Van De Loosdrecht, A. A., Germing, U., Haase, D. & Greenberg, P. L., 18 Aug 2016, In : Blood. 128, 7, p. 902-910 9 p.

Research output: Contribution to journalArticle

Open Access
File
Myelodysplastic Syndromes
Mortality
Hazards
Survival
Multicenter Studies
2015
52 Citations (Scopus)

Validation of WHO classification-based Prognostic Scoring System (WPSS) for myelodysplastic syndromes and comparison with the revised International Prognostic Scoring System (IPSS-R). A study of the International Working Group for Prognosis in Myelodysplasia (IWG-PM)

Della Porta, M. G., Tuechler, H., Malcovati, L., Schanz, J., Sanz, G., Garcia-Manero, G., Solé, F., Bennett, J. M., Bowen, D., Fenaux, P., Dreyfus, F., Kantarjian, H., Kuendgen, A., Levis, A., Cermak, J., Fonatsch, C., Le Beau, M. M., Slovak, M. L., Krieger, O., Luebbert, M. & 15 others, Maciejewski, J., Magalhaes, S. M. M., Miyazaki, Y., Pfeilstöcker, M., Sekeres, M. A., Sperr, W. R., Stauder, R., Tauro, S., Valent, P., Vallespi, T., van de Loosdrecht, A. A., Germing, U., Haase, D., Greenberg, P. L. & Cazzola, M., 13 Jul 2015, In : Leukemia. 29, 7, p. 1502-1513 12 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Cytogenetics
Anemia
Bone Marrow
Weights and Measures
2014
158 Citations (Scopus)

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo

Woll, P. S., Kjällquist, U., Chowdhury, O., Doolittle, H., Wedge, D. C., Thongjuea, S., Erlandsson, R., Ngara, M., Anderson, K., Deng, Q., Mead, A. J., Stenson, L., Giustacchini, A., Duarte, S., Giannoulatou, E., Taylor, S., Karimi, M., Scharenberg, C., Mortera-Blanco, T., Macaulay, I. C. & 28 others, Clark, S-A., Dybedal, I., Josefsen, D., Fenaux, P., Hokland, P., Holm, M. S., Cazzola, M., Malcovati, L., Tauro, S., Bowen, D., Boultwood, J., Pellagatti, A., Pimanda, J. E., Unnikrishnan, A., Vyas, P., Göhring, G., Schlegelberger, B., Tobiasson, M., Kvalheim, G., Constantinescu, S. N., Nerlov, C., Nilsson, L., Campbell, P. J., Sandberg, R., Papaemmanuil, E., Hellström-Lindberg, E., Linnarsson, S. & Jacobsen, S. E. W., 16 Jun 2014, In : Cancer Cell. 25, 6, p. 794-808 15 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Myelodysplastic Syndromes
Molecular Evolution
Stem Cells
2013
21 Citations (Scopus)

Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

MacCallum, S. F., Groves, M. J., James, J., Murray, K., Appleyard, V., Prescott, A. R., Drbal, A. A., Nicolaou, A., Cunningham, J., Haydock, S., Ganley, I. G., Westwood, N. J., Coates, P. J., Lain, S. & Tauro, S., 2013, In : Scientific Reports. 3, 1275.

Research output: Contribution to journalArticle

Autophagy
B-Cell Chronic Lymphocytic Leukemia
tenovin-6
Hematopoiesis
Genes
10 Citations (Scopus)

p53 and cell cycle independent dysregulation of autophagy in chronic lymphocytic leukaemia

Groves, M. J., Johnson, C. E., James, J., Prescott, A. R., Cunningham, J., Haydock, S., Pepper, C., Fegan, C., Pirrie, L., Westwood, N. J., Coates, P. J., Ganley, I. G. & Tauro, S., 2013, In : British Journal of Cancer. 109, October, p. 2432=2444 13 p.

Research output: Contribution to journalArticle

Autophagy
B-Cell Chronic Lymphocytic Leukemia
Cell Cycle
Sirtuins
Apoptosis
16 Citations (Scopus)

Post-transplant T cell chimerism predicts graft versus host disease but not disease relapse in patients undergoing an alemtuzumab based reduced intensity conditioned allogeneic transplant

Nikolousis, E., Robinson, S., Nagra, S., Brookes, C., Kinsella, F., Tauro, S., Jeffries, S., Griffiths, M., Mahendra, P., Cook, M., Paneesha, S., Lovell, R., Kishore, B., Chaganti, S., Malladi, R., Raghavan, M., Moss, P., Milligan, D. & Craddock, C., May 2013, In : Leukemia Research. 37, 5, p. 561-565 5 p.

Research output: Contribution to journalArticle

980 Citations (Scopus)

Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2

Massie, C. E., Nangalia, J., Baxter, E. J., Nice, F. L., Gundem, G., Wedge, D. C., Avezov, E., Li, J., Kollmann, K., Kent, D. G., Aziz, A., Godfrey, A. L., Hinton, J., Martincorena, I., Van Loo, P., Jones, A. V., Guglielmelli, P., Tarpey, P., Harding, H. P., Fitzpatrick, J. D. & 32 others, Goudie, C. T., Ortmann, C. A., Loughran, S. J., Raine, K., Jones, D. R., Butler, A. P., Teague, J. W., O'Meara, S., McLaren, S., Bianchi, M., Silber, Y., Dimitropoulou, D., Bloxham, D., Mudie, L., Maddison, M., Robinson, B., Keohane, C., Maclean, C., Hill, K., Orchard, K., Tauro, S., Du, M-Q., Greaves, M., Bowen, D., Huntly, B. J. P., Harrison, C. N., Cross, N. C. P., Ron, D., Vannucchi, A. M., Papaemmanuil, E., Campbell, P. J. & Green, A. R., 2013, In : New England Journal of Medicine. 369, 25, p. 2391-2405 15 p.

Research output: Contribution to journalArticle

Janus Kinase 2
Calreticulin
Mutation
Genes
Neoplasms
2012
3 Citations (Scopus)

Heterogeneity of p53-pathway Protein Expression in Chemosensitive Chronic Lymphocytic Leukemia: A Pilot Study

Groves, M. J., Maccallum, S. F., Boylan, M. T., Haydock, S., Cunningham, J., Gelly, K., Gowans, D., Kerr, R., Coates, P. J. & Tauro, S., 2012, In : Journal of Cancer. 3, p. 354-361 8 p.

Research output: Contribution to journalArticle

B-Cell Chronic Lymphocytic Leukemia
Proteins
Drug Therapy
Chlorambucil
Densitometry
1284 Citations (Scopus)

Revised international prognostic scoring system for myelodysplastic syndromes

Greenberg, P. L., Tuechler, H., Schanz, J., Sanz, G., Garcia-Manero, G., Solé, F., Bennett, J. M., Bowen, D., Fenaux, P., Dreyfus, F., Kantarjian, H., Kuendgen, A., Levis, A., Malcovati, L., Cazzola, M., Cermak, J., Fonatsch, C., Le Beau, M. M., Slovak, M. L., Krieger, O. & 14 others, Luebbert, M., Maciejewski, J., Magalhaes, S. M. M., Miyazaki, Y., Pfeilstöcker, M., Sekeres, M., Sperr, W. R., Stauder, R., Tauro, S., Valent, P., Vallespi, T., Van De Loosdrecht, A. A., Germing, U. & Haase, D., 2012, In : Blood. 120, 12, p. 2454-2465 12 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Cytogenetics
Ferritins
L-Lactate Dehydrogenase
Bone Marrow
2011
27 Citations (Scopus)

Absolute SILAC-compatible expression strain allows SUMO-2 copy number determination in clinical samples

Matic, I., Jaffray, E. G., Oxenham, S. K., Groves, M. J., Barratt, C. L. R., Tauro, S., Stanley-Wall, N. R. & Hay, R. T., Oct 2011, In : Journal of Proteome Research. 10, 10, p. 4869-4875 7 p.

Research output: Contribution to journalArticle

290 Citations (Scopus)

Clinical significance of SF3B1 mutations in myelodysplastic syndromes and myelodysplastic/myeloproliferative neoplasms

Malcovati, L., Papaemmanuil, E., Bowen, D. T., Boultwood, J., Della Porta, M. G., Pascutto, C., Travaglino, E., Groves, M. J., Godfrey, A. L., Ambaglio, I., Galli, A., Da Via, M. C., Conte, S., Tauro, S., Keenan, N., Hyslop, A., Hinton, J., Mudie, L. J., Wainscoat, J. S., Futreal, P. A. & 5 others, Stratton, M. R., Campbell, P. J., Hellstrom-Lindberg, E., Cazzola, M. & Assoc Italiana Ricerca Canc Grp, Int Canc Genome Consortium, 8 Dec 2011, In : Blood. 118, 24, p. 6239-6246 8 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Factors influencing a second myeloid malignancy in patients with Philadelphia-negative-7 or del(7q) clones during tyrosine kinase inhibitor therapy for chronic myeloid leukemia

Groves, M. J., Sales, M., Baker, L., Griffiths, M., Pratt, N. & Tauro, S., Jan 2011, In : Cancer Genetics. 204, 1, p. 39-44 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Predicted costs of iron-chelators in myelodysplastic syndromes: A 10-year analysis based on actual prevalence and red cell transfusion rates

Durairaj, S., Chew, S., Hyslop, A., Keenan, N., Groves, M. J. & Tauro, S., May 2011, In : American Journal of Hematology. 86, 5, p. 406-410 5 p.

Research output: Contribution to journalArticle

697 Citations (Scopus)

Somatic SF3B1 Mutation in Myelodysplasia with Ring Sideroblasts

Papaemmanuil, E., Cazzola, M., Boultwood, J., Malcovati, L., Vyas, P., Bowen, D., Pellagatti, A., Wainscoat, J. S., Hellstrom-Lindberg, E., Gambacorti-Passerini, C., Godfrey, A. L., Rapado, I., Cvejic, A., Rance, R., McGee, C., Ellis, P., Mudie, L. J., Stephens, P. J., McLaren, S., Massie, C. E. & 29 others, Tarpey, P. S., Varela, I., Nik-Zainal, S., Davies, H. R., Shlien, A., Jones, D., Raine, K., Hinton, J., Butler, A. P., Teague, J. W., Baxter, E. J., Score, J., Galli, A., Della Porta, M. G., Travaglino, E., Groves, M., Tauro, S., Munshi, N. C., Anderson, K. C., El-Naggar, A., Fischer, A., Mustonen, V., Warren, A. J., Cross, N. C. P., Green, A. R., Futreal, P. A., Stratton, M. R., Campbell, P. J. & Int Canc Genome Consortium, 2011, In : New England Journal of Medicine. 365, 15, p. 1384-1395 12 p.

Research output: Contribution to journalArticle

2010
66 Citations (Scopus)

Delta 160p53 is a novel N-terminal p53 isoform encoded by Delta 133p53 transcript

Marcel, V., Perrier, S., Aoubala, M., Ageorges, S., Groves, M. J., Diot, A., Fernandes, K., Tauro, S. & Bourdon, J-C., 5 Nov 2010, In : FEBS Letters. 584, 21, p. 4463-4468 6 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Dose-intensified treatment of Burkitt lymphoma and B-cell lymphoma unclassifiable, (with features intermediate between diffuse large B-cell lymphoma and Burkitt lymphoma) in young adults (protocols

Tauro, S., Cochrane, L., Lauritzsen, G. F., Baker, L., Delabie, J., Roberts, C., Mahendra, P. & Holte, H., Apr 2010, In : American Journal of Hematology. 85, 4, p. 261-263 3 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Factors predicting long-term survival after T-cell depleted reduced intensity allogeneic stem cell transplantation for acute myeloid leukemia

Craddock, C., Nagra, S., Peniket, A., Brookes, C., Buckley, L., Nikolousis, E., Duncan, N., Tauro, S., Yin, J., Liakopoulou, E., Kottaridis, P., Snowden, J., Milligan, D., Cook, G., Tholouli, B., Littlewood, T., Peggs, K., Vyas, P., Clark, F., Cook, M. & 2 others, MacKinnon, S. & Russell, N., Jun 2010, In : Haematologica. 95, 6, p. 989-995 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

Molecular characterisation of a recurrent, semi-cryptic RUNX1 translocation t(7;21) in myelodysplastic syndrome and acute myeloid leukaemia

Foster, N., Paulsson, K., Sales, M., Cunningham, J., Groves, M., O'Connor, N., Begum, S., Stubbs, T., McMullan, D. J., Griffiths, M., Pratt, N. & Tauro, S., Mar 2010, In : British Journal of Haematology. 148, 6, p. 938-943 6 p.

Research output: Contribution to journalArticle

2009
4 Citations (Scopus)

Autoimmune pancytopenia following combination chemotherapy for chronic lymphocytic leukaemia

MacCallum, S., Groves, M., Brass, D., Cunningham, J., Sales, M., Gelly, K. & Tauro, S., 2009, In : Journal of Clinical Pathology. 62, 5, p. 468-470 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Multifocal primary extranodal B-cell non-Hodgkin's lymphoma involving six extranodal sites

Craig, J., Brunton, J., Bayer, L., Walker, K., Oliver, B., Meiklejohn, D., Kernohan, N. & Tauro, S., Jan 2009, In : Journal of Clinical Pathology. 62, 1, p. 89-91 3 p.

Research output: Contribution to journalArticle

2005
388 Citations (Scopus)
458 Downloads (Pure)

Adoptive transfer of cytomegalovirus-specific CTL to stem cell transplant patients after selection by HLA–peptide tetramers

Cobbold, M., Khan, N., Pourgheysari, B., Tauro, S., McDonald, D., Osman, H., Assenmacher, M., Billingham, L., Steward, C., Crawley, C., Olavarria, E., Goldman, J., Chakraverty, R., Mahendra, P., Craddock, C. & Moss, P. A. H., 2005, In : Journal of Experimental Medicine. 202, 3, p. 379-386 8 p.

Research output: Contribution to journalArticle

Open Access
File
Adoptive Transfer
Cytomegalovirus
Patient Selection
Stem Cells
Transplants
187 Citations (Scopus)

Allogeneic stem-cell transplantation using a reduced-intensity conditioning regimen has the capacity to produce durable remissions and long-term disease-free survival in patients with high-risk acute myeloid leukemia and myelodysplasia

Tauro, S., Craddock, C., Peggs, K., Begum, G., Mahendra, P., Cook, G., Marsh, J., Milligan, D., Goldstone, A., Hunter, A., Khwaja, A., Chopra, R., Littlewood, T., Peniket, A., Parker, A., Jackson, G., Hale, G., Cook, M., Russell, N. & Mackinnon, S., 2005, In : Journal of Clinical Oncology. 23, 36, p. 9387-9393 7 p.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Acute Myeloid Leukemia
Disease-Free Survival
Allografts
Transplantation
2002
46 Citations (Scopus)

Functional disturbance of marrow stromal microenvironment in the myelodysplastic syndromes

Tauro, S., Hepburn, M. D., Peddie, C. M., Bowen, D. T. & Pippard, M. J., 2002, In : Leukemia. 16, 5, p. 785-790 6 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Coculture Techniques
Bone Marrow
Apoptosis
Interleukin-3
2001
44 Citations (Scopus)

Assessment of stromal function, and its potential contribution to deregulation of hematopoiesis in the myelodysplastic syndromes

Tauro, S., Hepburn, M. D., Bowen, D. T. & Pippard, M. J., 2001, In : Haematologica. 86, 10, p. 1038-1045 8 p.

Research output: Contribution to journalArticle

Myelodysplastic Syndromes
Hematopoiesis
Superoxides
Bone Marrow
Stromal Cells