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Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where Sven Lange is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Deubiquitinases: from mechanisms to their inhibition by small molecules
Lange, S. M., Armstrong, L. A. & Kulathu, Y., 6 Jan 2022, In: Molecular Cell. 82, 1, p. 15-29 15 p.Research output: Contribution to journal › Review article › peer-review
4 Citations (Scopus) -
Purification, crystallization and drug screening of the IRAK pseudokinases
Lange, S. M. & Kulathu, Y., 4 May 2022, Pseudokinases. Jura, N. & Murphy, J. M. (eds.). Academic Press, Vol. 667. p. 101-121 21 p. (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
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Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies
Armstrong, L. A., Lange, S. M., de Cesare, V., Matthews, S. P., Nirujogi, R. S., Cole, I., Hope, A., Cunningham, F., Toth, R., Mukherjee, R., Bojkova, D., Gruber, F., Gray, D., Wyatt, P. G., Cinatl, J., Dikic, I., Davies, P. & Kulathu, Y., 16 Jul 2021, In: PLoS ONE. 16, 7, 25 p., e0253364.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Citations (Scopus)33 Downloads (Pure) -
Dimeric structure of the pseudokinase IRAK3 suggests an allosteric mechanism for negative regulation
Lange, S., Nelen, M. I., Cohen, P. & Kulathu, Y., 4 Mar 2021, In: Structure. 29, 3, p. 238-251.e4 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile10 Citations (Scopus)100 Downloads (Pure) -
Linking K29-Ub chains to biology
Lange, S. M. & Kulathu, Y., Aug 2021, In: Nature Chemical Biology. 17, 8, p. 843-844 2 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile50 Downloads (Pure)