Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 8 Decent Work and Economic Growth
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Dive into the research topics where Thomas Eadsforth is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Research output
- 18 Article
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Crystallographic characterisation and development of bi-substrate inhibitors of coronavirus nsp14 methyltransferase
Georgiou, I., Robinson, C., O'Byrne, S. N., Matsuda, A., Grygier, P., Smith, C. D., O'Neill, S., Ahmad, S. A., Norval, S., Post, J. M., Groenewold, G. J. M., Urakova, N., Wanningen, P., Kresik, L., Plewka, J., Delpal, A., See, K., Eadsforth, T., Wierzbicka, K. & Decroly, E. & 7 others, , 6 Jan 2026, (E-pub ahead of print) In: RSC Medicinal Chemistry. 17, 2, p. 1015-1030 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile15 Downloads (Pure) -
Mechanistic Insights into Dual-Active Liver and Blood-Stage Antiplasmodials
Rawat, M., Boonyalai, T., Smidt, C., Luth, M. R., Chen, D., Plater, A., Post, J., Lin, D., McMillan, J., Eadsforth, T., Moliner Cubel, S., Billker, O., Rayner, J. C., Gamo, F.-J., Baragana, B., Winzeler, E. A. & Lee, M. C. S., 14 Jan 2026, In: MBio. 17, 1, p. e0242325 20 p., e02423-25.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Downloads (Pure) -
Biophysical analysis of an oligomerization-attenuated variant of the Leishmania donovani dynamin-1-like protein
Wuyts, E., Sundaramoorthy, R., Tulloch, L., Monsieurs, P., Eadsforth, T., Pintelon, I., Timmermans, J.-P., Dujardin, J.-C., Domagalska, M. A., Caljon, G., De Rycker, M., Postis, V., Wyllie, S. & Sterckx, Y.G.-J. (Lead / Corresponding author), Sept 2025, In: Molecular and Biochemical Parasitology. 263, 111691.Research output: Contribution to journal › Article › peer-review
Open AccessFile145 Downloads (Pure) -
Characterisation of RNA guanine-7 methyltransferase (RNMT) using a small molecule approach
Pearson, L.-A., Petit, A.-P., Mendoza Martinez, C., Bellany, F., Lin, D., Niven, S., Swift, R., Eadsforth, T., Fyfe, P., Paul, M., Postis, V., Hu, X., Cowling, V. & Gray, D. (Lead / Corresponding author), 17 Feb 2025, In: Biochemical Journal. 482, 4, p. 209-224 16 p., BCJ20240608.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Link opens in a new tab Citations (Scopus)71 Downloads (Pure) -
Pharmacological and structural understanding of the Trypanosoma cruzi proteasome provides key insights for developing site-specific inhibitors
Eadsforth, T. C., Torrie, L. S., Rowland, P., Edgar, E. V., MacLean, L. M., Paterson, C., Robinson, D. A., Shepherd, S. M., Thomas, J., Thomas, M., Gray, D., Postis, V. & De Rycker, M. (Lead / Corresponding author), Jan 2025, In: Journal of Biological Chemistry. 301, 1, 17 p., 108049.Research output: Contribution to journal › Article › peer-review
Open AccessFile3 Link opens in a new tab Citations (Scopus)105 Downloads (Pure)