Wilson, Timothy

Dr

  • United Kingdom

  • 789 Citations
  • 16 h-Index
20072019
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Fingerprint Dive into the research topics where Timothy Wilson is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 21 Similar Profiles
Catalytic RNA Medicine & Life Sciences
Catalysis Chemical Compounds
Riboswitch Medicine & Life Sciences
Acids Medicine & Life Sciences
Guanine Medicine & Life Sciences
Phosphates Medicine & Life Sciences
Guanidine Medicine & Life Sciences
RNA Medicine & Life Sciences

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Research Output 2007 2019

  • 789 Citations
  • 16 h-Index
  • 23 Article
  • 1 Chapter
2 Citations (Scopus)
38 Downloads (Pure)

Comparison of the Structures and Mechanisms of the Pistol and Hammerhead Ribozymes

Wilson, T. J., Liu, Y., Li, N-S., Dai, Q., Piccirilli, J. A. & Lilley, D. M. J., 2019, In : Journal of the American Chemical Society. 141, 19, p. 7865-7875 11 p.

Research output: Contribution to journalArticle

Open Access
File
Catalytic RNA
Conformations
Nucleophiles
Acids
Metal ions
63 Downloads (Pure)

Structure-guided design of a high affinity ligand for a riboswitch

Huang, L., Wang, J., Wilson, T. & Lilley, D., Apr 2019, In : RNA: a Publication of the RNA Society. 25, 4, p. 423-430 8 p.

Research output: Contribution to journalArticle

Open Access
File
Riboswitch
Guanidine
Ligands
Binding Sites
X-Rays
19 Citations (Scopus)
132 Downloads (Pure)

The structure of a nucleolytic ribozyme that employs a catalytic metal ion

Liu, Y., Wilson, T. & Lilley, D., May 2017, In : Nature Chemical Biology. 13, 5, p. 508-513 7 p.

Research output: Contribution to journalArticle

Open Access
File
Catalytic RNA
Metals
Ions
Phosphates
RNA
8 Citations (Scopus)
93 Downloads (Pure)

The structure of the Guanidine-III Riboswitch

Huang, L., Wang, J., Wilson, T. J. & Lilley, D. M. J., 16 Nov 2017, In : Cell Chemical Biology. 24, 11, p. 1407-1415.e2 12 p.

Research output: Contribution to journalArticle

Open Access
File
Riboswitch
Guanidine
Cations
Methylguanidine
Agmatine
34 Citations (Scopus)
101 Downloads (Pure)

Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer

Schmid, P., Pinder, S. E., Wheatley, D., Macaskill, J., Zammit, C., Hu, J., Price, R., Bundred, N., Hadad, S., Shia, A., Sarker, S. J., Lim, L., Gazinska, P., Woodman, N., Korbie, D., Trau, M., Mainwaring, P., Gendreau, S., Lackner, M. R., Derynck, M. & 6 others, Wilson, T. R., Butler, H., Earl, G., Parker, P., Purushotham, A. & Thompson, A., 10 Jun 2016, In : Journal of Clinical Oncology. 34, 17, p. 1987-1994 8 p.

Research output: Contribution to journalArticle

Open Access
File
Phosphatidylinositol 3-Kinases
Estrogen Receptors
Breast Neoplasms
Neoplasms
Therapeutics