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Keyphrases
Plasmodium Falciparum
83%
Plasmodium
54%
In Vivo Efficacy
50%
Phosphatidylinositol 4-kinase (PI4K)
50%
Kinase Inhibitor
33%
Multiple Stages
29%
Diaryl
25%
Methyltransferase Inhibitors
25%
Proteomic Approach
25%
ADME Profile
25%
PRMT1
25%
Humanized Mice
25%
Dual-active
25%
Malaria Infection
25%
7-Azaindole
25%
Life Cycle Stages
25%
Target Landscape
25%
N-arylacetamides
25%
Chemical Proteomics
25%
Novel Inhibitors
25%
1,5-naphthyridine
25%
Disease Model
25%
AUY922
25%
Anticancer
16%
Protein Kinase
16%
Malaria Parasite
16%
ATP6
16%
Physicochemical Properties
16%
Scid
16%
Structure-activity Relationship
16%
Mouse Model
16%
Falciparum Malaria
16%
Chemotype
16%
Resistance Risk
12%
AZD0156
8%
HERG Channel
8%
Arginine Methylation
8%
Repositioning Strategy
8%
Compound Mechanism
8%
New Drug Candidate
8%
Histone Arginine Methylation
8%
Novel Mechanism
8%
Ataxia Telangiectasia mutated Kinase
8%
Multi-lobe
8%
MINK1
8%
Pharmacokinetic Profile
8%
Histone Acetylation
8%
Lipid Kinase
8%
Low Selectivity
8%
High Selectivity
8%
Immunology and Microbiology
Kinase
100%
Phosphotransferase
100%
Plasmodium falciparum
81%
Parasite
62%
Antimalarial Activity
54%
In Vitro
50%
Plasmodium
47%
Hemozoin
25%
Humanized Mouse
25%
Life Cycle Stage
25%
Arginine
25%
Proteomics
25%
Proteinase
25%
Protease
25%
Malaria
22%
Acetic Acid Derivative
16%
Transfer RNA
16%
Resistome
16%
Isoleucine
16%
Cross-Resistance
16%
Methylation
15%
Mouse Model
14%
Antimalarial Agent
14%
Chemotype
11%
Life Cycle
11%
Histone
10%
Heme
8%
Gametocyte
8%
Gamete
8%
Genetic Resistance
8%
Structure Activity Relation
8%
Molecular Docking
8%
Clustered Regularly Interspaced Short Palindromic Repeat
8%
Competitive Inhibition
6%
Ataxia Telangiectasia
6%
Protein Family
5%
Antimalarial Drug Resistance
5%
Lysine
5%
Parasite Development
5%
Pharmacophore
5%
Acetylation
5%
Gene Expression
5%
Pharmacology, Toxicology and Pharmaceutical Science
Plasmodium falciparum
75%
Phosphotransferase Inhibitor
50%
Plasmodium
41%
Antimalarial Agent
33%
Phosphatidylinositol Kinase
25%
Acinetobacter Baumannii
25%
Combination Drug
25%
Antimalarial Activity
25%
Hemozoin
25%
Protein Kinases
25%
Naphthyridine Derivative
25%
Pharmacokinetics
25%
Absorption Distribution Metabolism Excretion
25%
Protein Arginine Methyltransferase
25%
Parasite
25%
Methyltransferase Inhibitor
25%
Histone
16%
Arginine
16%
Drug Resistance
14%
Mouse Model
12%
Malaria Falciparum
12%
Antiinfective Agent
12%
Antibiotics
12%
Wound Infection
12%
Heme
12%
Parasitemia
12%
Cytotoxicity
12%
Lipid
12%
Lysine
8%
Genetic Resistance
8%
Lead Compound
6%
Eravacycline
6%
Brilacidin
6%
Murine
6%
Infection
6%
Acinetobacter
6%
Infectious Agent
6%
Triclosan
6%
Hospital Infection
6%
Adenosine Triphosphatase
6%
Multidrug Resistance Protein 1
6%
Hematin
6%
Luciferase
6%
Rodent Malaria
6%
Benzimidazole
6%
Chloroquine
6%
Aminopyridine
6%
Detoxication
6%
Plasmodium berghei
6%
Antibiotic Resistance
6%