Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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SDG 4 Quality Education
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Collaborations and top research areas from the last five years
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Green PROTACs – enabling small molecule (re)programming and manipulation of plant biology
Ciulli, A. (Investigator), Drost, H. (Investigator), Hemsley, P. (Investigator) & Zachariae, U. (Investigator)
1/10/25 → 3/03/27
Project: Research
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Development of CatSper Assay
Barratt, C. (Investigator), Gilbert, I. (Investigator), Johnston, Z. (Investigator), Martins Da Silva, S. (Investigator), Swedlow, J. (Investigator) & Zachariae, U. (Investigator)
6/12/24 → 5/01/28
Project: Research
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Breaking the Membrane Permeability Barrier for Antimicrobials in Gram-negative Bacteria (Vacation Scholarship 2017)
Zachariae, U. (Investigator)
Project: Research
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GPU-Based Machine Learning System For Fundamental Biological Research
Barton, G. (Investigator), Gilbert, I. (Investigator), Lamond, A. (Investigator), Owen-Hughes, T. (Investigator), Pisliakov, A. (Investigator), Schweikert, G. (Investigator), Sknepnek, R. (Investigator), Swedlow, J. (Investigator), Weijer, K. (Investigator) & Zachariae, U. (Investigator)
Biotechnology and Biological Sciences Research Council
1/08/21 → 31/07/22
Project: Research
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A DNA Rotary Pump
Spankie, T. J., Zachariae, U. (Lead / Corresponding author) & Cockroft, S. L. (Lead / Corresponding author), 29 Aug 2026, (E-pub ahead of print) In: ACS Nano. 14 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Downloads (Pure) -
A model for drug transport across two membranes of Gram-negative bacteria by an MFS tripartite assembly
Zhong, Z., Maimaiti, T., Jackson, M. L., Dong, R., Gao, X., Ouyang, Q., Wang, W., Guo, J., Li, S., Shang, W., Liu, H., Jiang, H., Zhang, S., Zachariae, U. (Lead / Corresponding author), Luisi, B. F. (Lead / Corresponding author), Chao, Y. (Lead / Corresponding author) & Du, D. (Lead / Corresponding author), 5 May 2026, In: Nature Communications. 17, 15 p., 4039.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)8 Downloads (Pure) -
FMOPhore for hotspot identification and efficient fragment-to-lead growth strategies
Ibrahim, P. E. G. F. (Lead / Corresponding author), Altmann, S., Zachariae, U., Horn, D., Gilbert, I. H. & Bodkin, M. J., 28 Apr 2026, In: Nature Communications. 17, 17 p., 5813.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)11 Downloads (Pure) -
A widely-occurring family of pore-forming effectors broadens the impact of the Serratia Type VI secretion system
Reglinski, M., Hurst, Q. W., Williams, D. J., Gierlinski, M., Şahin, A. T., Mathers, K., Ostrowski, A., Bergkessel, M., Zachariae, U., Pitt, S. J. & Coulthurst, S. J. (Lead / Corresponding author), 1 Dec 2025, In: EMBO Journal. 44, 23, p. 6892-6918 27 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile8 Link opens in a new tab Citations (Scopus)34 Downloads (Pure) -
In silico characterization of the gating and selectivity mechanism of the human TPC2 cation channel
Sahin, A. T. & Zachariae, U. (Lead / Corresponding author), 5 May 2025, In: Journal of General Physiology. 157, 3, 20 p., e202313506.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Link opens in a new tab Citations (Scopus)83 Downloads (Pure)
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PhD defence/ examination
Zachariae, U. (Examiner)
13 Aug 2024Activity: Examination types › Examination
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Data-Driven Analysis Of Molecular Substructures That Help To Enhance Drug Permeation And Escape Efflux In Gram-Negative Bacteria
Zachariae, U. (Speaker)
19 Aug 2024Activity: Talk or presentation types › Invited talk
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Why are computational chemists making up their data?
Zachariae, U. (Contributor)
28 May 2024Activity: Other activity types › Public engagement and outreach - media article or participation
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Accessibility Video Project - Opening our Doors to the Public
Cameron, A. (Organiser), Soave, S. (Contributor), Stanley-Wall, N. (Contributor), Rosazza, T. (Contributor), Ganley, I. (Contributor), Singh, F. (Contributor), Sammler, E. (Contributor), Filipe Soares, R. (Contributor), Spinelli, L. (Contributor), Findlay, G. (Contributor), Hogg, E. (Contributor), Espejo Serrano, C. (Contributor), Prescott, A. (Contributor), Januschke, J. (Contributor), Pelisch, F. (Contributor), Bel Borja, L. (Contributor), Horn, D. (Contributor), Ridgway, M. (Contributor), Owen-Hughes, T. (Contributor), Sundaramoorthy, R. (Contributor), Barton, G. (Contributor), Sknepnek, R. (Contributor), Zachariae, U. (Contributor), Duce, S. (Contributor), McKim, S. (Contributor), Pugh, L. (Contributor), Griffin, J. (Contributor), Hein, I. (Contributor), Gilroy, E. M. (Contributor), McKenzie, G. (Contributor), Ly, T. (Contributor), Kar, A. (Contributor), Hastie, J. (Contributor), Postis, V. (Contributor), Dawson, A. (Contributor), Fyfe, P. (Contributor), Semenova, O. (Contributor), Robinson, D. (Contributor), Gray, D. (Contributor), Cabrita Gulyurtlu, S. (Contributor), Zollman, D. (Contributor), Spiteri, V. (Contributor) & Webb, T. (Contributor)
2022 → …Activity: Other activity types › Other