Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
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Breaking the Membrane Permeability Barrier for Antimicrobials in Gram-negative Bacteria (Vacation Scholarship 2017)
Zachariae, U. (Investigator)
Project: Research
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GPU-Based Machine Learning System For Fundamental Biological Research
Barton, G. (Investigator), Gilbert, I. (Investigator), Lamond, A. (Investigator), Owen-Hughes, T. (Investigator), Pisliakov, A. (Investigator), Schweikert, G. (Investigator), Sknepnek, R. (Investigator), Swedlow, J. (Investigator), Weijer, K. (Investigator) & Zachariae, U. (Investigator)
Biotechnology and Biological Sciences Research Council
1/08/21 → 31/07/22
Project: Research
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Hidden Fats: Allosteric and Direct Mechanisms of Lipid Signalling Through GPCRs (CASE Studentship)
Zachariae, U. (Investigator)
Biotechnology and Biological Sciences Research Council
1/04/14 → 31/03/19
Project: Research
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A widely-occurring family of pore-forming effectors broadens the impact of the Serratia Type VI secretion system
Reglinski, M., Hurst, Q. W., Williams, D. J., Gierlinski, M., Şahin, A. T., Mathers, K., Ostrowski, A., Bergkessel, M., Zachariae, U., Pitt, S. J. & Coulthurst, S. J. (Lead / Corresponding author), 1 Dec 2025, In: EMBO Journal. 44, 23, p. 6892-6918 27 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)1 Downloads (Pure) -
In silico characterization of the gating and selectivity mechanism of the human TPC2 cation channel
Sahin, A. T. & Zachariae, U. (Lead / Corresponding author), 5 May 2025, In: Journal of General Physiology. 157, 3, 20 p., e202313506.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Citation (Scopus)45 Downloads (Pure) -
Mechanism of negative µ-opioid receptor modulation by sodium ions
Thomson, N. J. & Zachariae, U. (Lead / Corresponding author), 2 Jan 2025, In: Structure. 33, 1, p. 196-205.e2 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus) -
Systematic Analysis of Biomolecular Conformational Ensembles with PENSA
Vögele, M. (Lead / Corresponding author), Thomson, N. J., Truong, S. T., McAvity, J., Zachariae, U. & Dror, R. O. (Lead / Corresponding author), 2 Jan 2025, In: Journal of Chemical Physics. 162, 1, 13 p., 014101.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Citations (Scopus)98 Downloads (Pure) -
Accurate prediction of dynamic protein-ligand binding using P-score ranking
E. G. F. Ibrahim, P., Zuccotto, F., Zachariae, U., Gilbert, I. & Bodkin, M. (Lead / Corresponding author), 30 Jul 2024, In: Journal of Computational Chemistry. 45, 20, p. 1762-1778 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)120 Downloads (Pure)
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Data-Driven Analysis Of Molecular Substructures That Help To Enhance Drug Permeation And Escape Efflux In Gram-Negative Bacteria
Zachariae, U. (Speaker)
19 Aug 2024Activity: Talk or presentation types › Invited talk
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Why are computational chemists making up their data?
Zachariae, U. (Contributor)
28 May 2024Activity: Other activity types › Public engagement and outreach - media article or participation
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PhD defence/ examination
Zachariae, U. (Examiner)
13 Aug 2024Activity: Examination types › Examination
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Broad Spectrum Antibiotics Meeting
Zachariae, U. (Speaker)
2022Activity: Talk or presentation types › Invited talk