Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Projects
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Early Career - Target Protein Degradation Network (Joint with University of Glasgow and University of Strathclyde)
Ciulli, A. (Investigator), Eugui Anta, A. (Investigator), Farnaby, W. (Investigator), Haubrich, K. (Investigator), Mojsa, B. (Investigator) & Spiteri, V. (Investigator)
Project: Research
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Dual E3 ligase recruitment by monovalent degraders for tunable SMARCA 2/4 degradation
Spiteri, V. A., Segal, D., Correa-Sáez, A., Iso, K., Casement, R., Muñoz i Ordoño, M., Nakasone, M. A., Sathe, G., Schätz, C., Peters, H. E., Doward, M., Kainacher, L., Cowan, A. D., Ciulli, A. (Lead / Corresponding author) & Winter, G. E. (Lead / Corresponding author), 12 May 2026, In: Nature Chemical Biology.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Link opens in a new tab Citation (Scopus)29 Downloads (Pure) -
Targeted protein degradation for cancer therapy
Hinterndorfer, M., Spiteri, V. A., Ciulli, A. (Lead / Corresponding author) & Winter, G. E. (Lead / Corresponding author), Jul 2025, In: Nature Reviews Cancer. 25, 7, p. 493-516 24 p., e1487.Research output: Contribution to journal › Review article › peer-review
Open AccessFile117 Link opens in a new tab Citations (Scopus)423 Downloads (Pure) -
Confounding Factors in Targeted Degradation of Short-Lived Proteins
Vetma, V., Perez, L. C., Eliaš, J., Stingu, A., Kombara, A., Gmaschitz, T., Braun, N., Ciftci, T., Dahmann, G., Diers, E., Gerstberger, T., Greb, P., Kidd, G., Kofink, C., Puoti, I., Spiteri, V., Trainor, N., Weinstabl, H., Westermaier, Y. & Whitworth, C. & 6 others, , 19 Jul 2024, In: ACS Chemical Biology. 19, 7, p. 1484-1494 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile31 Link opens in a new tab Citations (Scopus)88 Downloads (Pure) -
Design of a Cereblon construct for crystallographic and biophysical studies of protein degraders
Kroupova, A., Spiteri, V., Rutter, Z., Furihata, H., Darren, D., Ramachandran, S., Chakraborti, S., Haubrich, K., Pethe, J., Gonzales, D., Wijaya, A., Rodriguez-Rios, M., Sturbaut, M., Lynch, D., Farnaby, W., Nakasone, M., Zollman, D. (Lead / Corresponding author) & Ciulli, A. (Lead / Corresponding author), 15 Oct 2024, In: Nature Communications. 15, 14 p., 8885.Research output: Contribution to journal › Article › peer-review
Open AccessFile20 Link opens in a new tab Citations (Scopus)174 Downloads (Pure) -
Breaking free from the crystal lattice: Structural biology in solution to study protein degraders
Haubrich, K., Spiteri, V., Farnaby, W., Sobott, F. & Ciulli, A. (Lead / Corresponding author), Apr 2023, In: Current Opinion in Structural Biology. 79, 9 p., 102534.Research output: Contribution to journal › Review article › peer-review
Open AccessFile13 Link opens in a new tab Citations (Scopus)306 Downloads (Pure)
Activities
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Modern Medicines - Cafe Science and Lab Tour
Kidd, G. (Speaker), Frost, A. (Speaker) & Spiteri, V. (Speaker)
28 Feb 2024 → 4 Mar 2024Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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CeTPD Outreach: Family Fun with Women in STEM
Gulyurtlu, S. (Contributor), Spiteri, V. (Participant), Puoti, I. (Participant), Chakraborti, S. (Participant), Diehl, C. (Participant), Darren, D. (Participant) & O'Connor, S. (Participant)
11 Mar 2023Activity: Other activity types › Public engagement and outreach - festival/exhibition
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Family Fun with Women in STEM - Dundee Women's Festival 2023
Cameron, A. (Organiser), Doran, H. (Organiser), Rogers, A. (Organiser), Morriss, C. (Organiser), Robertson-Albertyn, S. (Participant), Escudero-Martinez, C. (Participant), Sanchez Avila, A. (Participant), Keitel, A. (Participant), Cabrita Gulyurtlu, S. (Participant), Diehl, C. (Participant), Chakraborti, S. (Participant), Darren, D. (Participant), O'Connor, S. (Participant), Puoti, I. (Participant), Spiteri, V. (Participant), Gold, L. (Participant), Glennie, L. (Participant), Hannah, M. (Participant), Ahmad, S. (Participant), Atanasova, T. (Participant), Buck, B. (Participant), Keitel, C. (Participant), Sen Alpay, S. (Participant), Burton, K. (Participant) & Sobreira, C. (Participant)
11 Mar 2023Activity: Other activity types › Public engagement and outreach - festival/exhibition
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CeTPD Braeview visit June 2023
Kidd, G. (Organiser), Hardee, E. (Organiser), Cabrita Gulyurtlu, S. (Organiser), Kroupova, A. (Contributor), Chakraborti, S. (Contributor), Rodriguez-Rios, M. (Contributor), Correa Saez, A. (Contributor), Krstev, J. (Contributor), McAulay, K. (Contributor), Simpson, L. (Contributor), Spiteri, V. (Contributor), Wijaya, A. (Contributor) & Perez Areales, J. (Contributor)
15 Jun 2023Activity: Other activity types › Schools engagement
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CeTPD Outreach Cafe Science - Day 1
Cabrita Gulyurtlu, S. (Organiser), Wasim, S. (Organiser), Kidd, G. (Contributor), Spiteri, V. (Speaker), Frost, A. (Speaker), Chakraborti, S. (Contributor) & Diehl, C. (Contributor)
15 May 2023Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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