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Vetma, Vesna

Dr

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20212024

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  • 2024

    Confounding Factors in Targeted Degradation of Short-Lived Proteins

    Vetma, V., Perez, L. C., Eliaš, J., Stingu, A., Kombara, A., Gmaschitz, T., Braun, N., Ciftci, T., Dahmann, G., Diers, E., Gerstberger, T., Greb, P., Kidd, G., Kofink, C., Puoti, I., Spiteri, V., Trainor, N., Weinstabl, H., Westermaier, Y. & Whitworth, C. & 6 others, Ciulli, A., Farnaby, W., McAulay, K., Frost, A. B., Chessum, N. & Koegl, M. (Lead / Corresponding author), 19 Jul 2024, In: ACS Chemical Biology. 19, 7, p. 1484-1494 11 p.

    Research output: Contribution to journal › Article › peer-review

    11 Citations (Scopus)

  • Targeting cancer with small molecule pan-KRAS degraders

    Popow, J., Farnaby, W., Gollner, A., Kofink, C., Fischer, G., Wurm, M., Zollman, D., Wijaya, A., Mischerikow, N., Hasenoehrl, C., Prokofeva, P., Arnhof, H., Arce-Solano, S., Bell, S., Boeck, G., Diers, E., Frost, A. B., Goodwin-Tindall, J., Karolyi-Oezguer, J. & Khan, S. & 23 others, Klawatsch, T., Koegl, M., Kousek, R., Kratochvil, B., Kropatsch, K., Lauber, A. A., McLennan, R., Olt, S., Peter, D., Petermann, O., Roessler, V., Stolt-Bergner, P., Strack, P., Strauss, E., Trainor, N., Vetma, V., Whitworth, C., Zhong, S., Quant, J., Weinstabl, H., Kuster, B., Ettmayer, P. (Lead / Corresponding author) & Ciulli, A. (Lead / Corresponding author), 20 Sept 2024, In: Science. 385, 6715, p. 1338-1347 10 p.

    Research output: Contribution to journal › Article › peer-review

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    23 Citations (Scopus)
    256 Downloads (Pure)
  • 2022

    A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo

    Kofink, C., Trainor, N., Mair, B., Wöhrle, S., Wurm, M., Mischerikow, N., Roy, M. J., Bader, G., Greb, P., Garavel, G., Diers, E., McLennan, R., Whitworth, C., Vetma, V., Rumpel, K., Scharnweber, M., Fuchs, J. E., Gerstberger, T., Cui, Y. & Gremel, G. & 10 others, Chetta, P., Hopf, S., Budano, N., Rinnenthal, J., Gmaschitz, G., Mayer, M., Koegl, M., Ciulli, A., Weinstabl, H. (Lead / Corresponding author) & Farnaby, W. (Lead / Corresponding author), 10 Oct 2022, In: Nature Communications. 13, 15 p., 5969.

    Research output: Contribution to journal › Article › peer-review

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    124 Citations (Scopus)
    281 Downloads (Pure)
  • 2021

    Trivalent PROTACs enhance protein degradation via combined avidity and cooperativity

    Imaide, S., Riching, K. M., Makukhin, N., Vetma, V., Whitworth, C., Hughes, S. J., Trainor, N., Mahan, S. D., Murphy, N., Cowan, A., Chan, K.-H., Craigon, C., Test, A., Maniai, C., Urh, M., Daniels, D. L. & Ciulli, A. (Lead / Corresponding author), Nov 2021, In: Nature Chemical Biology. 17, 11, p. 1157-1167 11 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
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    155 Citations (Scopus)
    266 Downloads (Pure)