Personal profile

Education/Academic qualification

Doctor of Philosophy

Bachelor of Arts, University of Cambridge

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Messenger RNA Medicine & Life Sciences
Methylation Medicine & Life Sciences
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Transcriptional Activation Medicine & Life Sciences
Methyltransferases Medicine & Life Sciences
Transcription Chemical Compounds
Cell Proliferation Medicine & Life Sciences
Random access storage Chemical Compounds

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Research Output 2002 2018

mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II-dependent transcription

Varshney, D., Lombardi, O., Schweikert, G., Dunn, S., Suska, O. & Cowling, V. May 2018 In : Cell Reports. 23, 5, p. 1530-1542 13 p.

Research output: Contribution to journalArticle

Open Access
File
RNA Polymerase II
Methyltransferases
Random access storage
Transcription
Messenger RNA

Positioning Europe for the EPITRANSCRIPTOMICS challenge

Jantsch, M. , Quattrone, A. , O'Connell, M. , Helm, M. , Frye, M. , Macias-Gonzales, M. , Ohman, M. , Ameres, S. , Willems, L. , Fuks, F. , Oulas, A. , Vanacova, S. , Nielsen, H. , Bousquet-Antonelli, C. , Motorin, Y. , Roignant, J-Y. , Balatsos, N. , Dinnyes, A. , Baranov, P. , Kelly, V. & 40 others Lamm, A., Rechavi, G., Pelizzola, M., Liepins, J., Holodnuka Kholodnyuk, I., Zammit, V., Ayers, D., Drablos, F., Dahl, J. A., Bujnicki, J., Jeronimo, C., Almeida, R., Neagu, M., Costache, M., Bankovic, J., Banovic, B., Kyselovic, J., Valor, L. M., Selbert, S., Pir, P., Demircan, T., Cowling, V., Schäfer, M., Rossmanith, W., Lafontaine, D., David, A., Carre, C., Lyko, F., Schaffrath, R., Schwartz, S., Verdel, A., Klungland, A., Purta, E., Timotijevic, G., Cardona, F., Davalos, A., Ballana, E., O Carroll, D., Ule, J. & Fray, R. 9 May 2018 In : RNA Biology. p. 1-8 8 p.

Research output: Contribution to journalArticle

Epigenomics
DNA
RNA
Research
Regeneration

c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production

Dunn, S., Lombardi, O. & Cowling, V. 20 Jan 2017 In : Biochemical Journal. 474, 3, p. 377-384 8 p.

Research output: Contribution to journalArticle

Open Access
File
Methylation
Random access storage
Ribosomal RNA
Messenger RNA
Cell Nucleus Active Transport

Regulation and function of CMTR1-dependent mRNA cap methylation

Inesta-Vaquera, F. & Cowling, V. H. Nov 2017 In : Wiley Interdisciplinary Reviews: RNA. 8, 6, p. 1-6 6 p., e1450

Research output: Contribution to journalReview article

Methylation
Ribose
Innate Immunity
Messenger RNA
Nucleotides

Press / Media

£2.5million MRC senior fellowship award for cancer researcher

Victoria Cowling

6/08/137/08/13

2 items of media coverage

Press/Media: Research

Thesis

Cell cycle-dependent regulation of the human RNA cap methyltransferase (RNMT)

Author: Aregger, M., 2013

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Identification and functional characterisation of RAM, a novel and essential component of RNA guanine-7 methylation

Author: Gonatopoulos-Pournatzis, T., 2012

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Investigating the cellular mechanisms that determine RNMT dependency in breast cancer cells

Author: Dunn, S., 2014

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Investigating the role and regulation of mRNA capping in pluripotency and differentiation

Author: Suska, O., 2017

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Investigating the role of mRNA capping enzyme in C-MYC function

Author: Lombardi, O., 2017

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy