Cowling, Victoria

Professor

20022023
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Personal profile

Education/Academic qualification

Doctor of Philosophy

Bachelor of Arts, University of Cambridge

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Messenger RNA Medicine & Life Sciences
Methylation Medicine & Life Sciences
Methyltransferases Medicine & Life Sciences
RNA Polymerase II Medicine & Life Sciences
Transcriptional Activation Medicine & Life Sciences
mRNA guanylyltransferase Medicine & Life Sciences
Breast Neoplasms Medicine & Life Sciences
Genes Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2023

Research Output 2002 2019

3 Downloads (Pure)

CAPAM: the mRNA cap adenosine N6 methyltransferase

Cowling, V., 1 Mar 2019, In : Trends in Biochemical Sciences. 44, 3, p. 183-185 3 p., 1545.

Research output: Contribution to journalArticle

Open Access
File
mRNA guanylyltransferase
Methyltransferases
Adenosine
Messenger RNA
Methylation
6 Downloads (Pure)

Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells

Dunn, S., Lombardi, O., Lukoszek, R. & Cowling, V., 17 Apr 2019, In : Open Biology. 9, 4, p. 1-15 15 p., 190052.

Research output: Contribution to journalArticle

Open Access
File
guanine
methyltransferases
Methyltransferases
breast neoplasms
Cells
4 Citations (Scopus)
23 Downloads (Pure)

DHX15 regulates CMTR1-dependent gene expression and cell proliferation

Inesta-Vaquera, F., Chaugule, V. K., Galloway, A., Chandler, L., Rojas-Fernandez, A., Weidlich, S., Peggie, M. & Cowling, V., 18 Jun 2018, In : Life Science Alliance. 1, 3, 18 p., e201800092.

Research output: Contribution to journalArticle

Open Access
File
RNA Polymerase II
Cell Proliferation
Ribosomes
Gene Expression
Messenger RNA
5 Citations (Scopus)
19 Downloads (Pure)

mRNA cap methyltransferase, RNMT-RAM, promotes RNA pol II-dependent transcription

Varshney, D., Lombardi, O., Schweikert, G., Dunn, S., Suska, O. & Cowling, V., May 2018, In : Cell Reports. 23, 5, p. 1530-1542 13 p.

Research output: Contribution to journalArticle

Open Access
File
RNA Polymerase II
Methyltransferases
Random access storage
Transcription
Messenger RNA
3 Citations (Scopus)
Open Access
Cells
Messenger RNA
RNA Polymerase II
RNA
Cell Physiological Phenomena

Press / Media

£2.5million MRC senior fellowship award for cancer researcher

Victoria Cowling

6/08/137/08/13

2 items of media coverage

Press/Media: Research

Thesis

Cell cycle-dependent regulation of the human RNA cap methyltransferase (RNMT)

Author: Aregger, M., 2013

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Identification and functional characterisation of RAM, a novel and essential component of RNA guanine-7 methylation

Author: Gonatopoulos-Pournatzis, T., 2012

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Investigating the cellular mechanisms that determine RNMT dependency in breast cancer cells

Author: Dunn, S., 2014

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Investigating the role and regulation of mRNA capping in pluripotency and differentiation

Author: Suska, O., 2017

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Investigating the role of mRNA capping enzyme in C-MYC function

Author: Lombardi, O., 2017

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy