Cowling, Victoria

Professor

20022023
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Personal profile

Education/Academic qualification

Doctor of Philosophy

Bachelor of Arts, University of Cambridge

Fingerprint Dive into the research topics where Victoria Cowling is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Messenger RNA Medicine & Life Sciences
Methylation Medicine & Life Sciences
Methyltransferases Medicine & Life Sciences
RNA Polymerase II Medicine & Life Sciences
Gene expression Chemical Compounds
Transcriptional Activation Medicine & Life Sciences
mRNA guanylyltransferase Medicine & Life Sciences
Transcription Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Projects 2013 2023

Research Output 2002 2019

1 Citation (Scopus)
47 Downloads (Pure)

CAPAM: the mRNA cap adenosine N6 methyltransferase

Cowling, V., 1 Mar 2019, In : Trends in Biochemical Sciences. 44, 3, p. 183-185 3 p., 1545.

Research output: Contribution to journalArticle

Open Access
File
mRNA guanylyltransferase
Methyltransferases
Adenosine
Messenger RNA
Methylation
22 Downloads (Pure)

Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: Insights from accelerated molecular dynamics simulations

Bueren-Calabuig, J., Bage, M., Cowling, V. & Pisliakov, A., 19 Sep 2019, In : Nucleic Acids Research. 47, 16, p. 8675-8692 18 p., gkz613.

Research output: Contribution to journalArticle

Open Access
File
Guanine
Methyltransferases
Molecular Dynamics Simulation
RNA
S-Adenosylmethionine
4 Citations (Scopus)
28 Downloads (Pure)

mRNA cap regulation in mammalian cell function and fate

Galloway, A. & Cowling, V., Mar 2019, In : Biochimica et Biophysica Acta - Gene Regulatory Mechanisms. 1862, 3, p. 270-279 10 p.

Research output: Contribution to journalReview article

Open Access
File
Cells
Messenger RNA
RNA Polymerase II
RNA
Cell Physiological Phenomena
47 Downloads (Pure)

Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells

Dunn, S., Lombardi, O., Lukoszek, R. & Cowling, V., 17 Apr 2019, In : Open Biology. 9, 4, p. 1-15 15 p., 190052.

Research output: Contribution to journalArticle

Open Access
File
guanine
methyltransferases
Methyltransferases
breast neoplasms
Cells
8 Citations (Scopus)
85 Downloads (Pure)

DHX15 regulates CMTR1-dependent gene expression and cell proliferation

Inesta-Vaquera, F., Chaugule, V. K., Galloway, A., Chandler, L., Rojas-Fernandez, A., Weidlich, S., Peggie, M. & Cowling, V., 18 Jun 2018, In : Life Science Alliance. 1, 3, 18 p., e201800092.

Research output: Contribution to journalArticle

Open Access
File
Cell proliferation
Gene expression
gene expression
RNA
cell proliferation

Press / Media

£2.5million MRC senior fellowship award for cancer researcher

Victoria H. Cowling

6/08/137/08/13

2 items of Media coverage

Press/Media: Research

Thesis

Cell cycle-dependent regulation of the human RNA cap methyltransferase (RNMT)

Author: Aregger, M., 2013

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Identification and functional characterisation of RAM, a novel and essential component of RNA guanine-7 methylation

Author: Gonatopoulos-Pournatzis, T., 2012

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Investigating the cellular mechanisms that determine RNMT dependency in breast cancer cells

Author: Dunn, S., 2014

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File

Investigating the role and regulation of mRNA capping in pluripotency and differentiation

Author: Suska, O., 2017

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

Investigating the role of mRNA capping enzyme in C-MYC function

Author: Lombardi, O., 2017

Supervisor: Cowling, V. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy

File