De Cesare, Virginia

Dr

  • 107 Citations
  • 6 h-Index
20162018
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Fingerprint Dive into the research topics where Virginia De Cesare is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 83 Similar Profiles
Ubiquitin Medicine & Life Sciences
Lithocholic Acid Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Phosphorylation Chemical Compounds
Genomic Instability Medicine & Life Sciences
Cyclin D1 Medicine & Life Sciences
Androgen Receptors Medicine & Life Sciences
Drug Discovery Medicine & Life Sciences

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Research Output 2016 2018

  • 107 Citations
  • 6 h-Index
  • 7 Article
19 Citations (Scopus)
61 Downloads (Pure)

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

Kwasna, D., Rehman, S. A. A., Natarajan, J., Matthews, S., Madden, R., De Cesare, V., Weidlich, S., Virdee, S., Ahel, I., Gibbs-Seymour, I. & Kulathu, Y., 5 Apr 2018, In : Molecular Cell. 70, 1, p. 150-164.e6 15 p.

Research output: Contribution to journalArticle

Open Access
File
Genomic Instability
Ubiquitin
Polyubiquitin
DNA Damage
Catalysis
1 Citation (Scopus)
73 Downloads (Pure)

Inhibiting Multiple Deubiquitinases to Reduce Androgen Receptor Expression in Prostate Cancer Cells

de Las Pozas, A., Reiner, T., De Cesare, V., Trost, M. & Perez-Stable, C., 3 Sep 2018, In : Scientific Reports. 8, 1, 16 p., 13146.

Research output: Contribution to journalArticle

Open Access
File
Androgen Receptors
Prostatic Neoplasms
Castration
Histones
Messenger RNA
6 Citations (Scopus)
56 Downloads (Pure)

The MALDI TOF E2/E3 ligase assay as universal tool for drug discovery in the ubiquitin pathway

De Cesare, V., Johnson, C., Barlow, V., Hastie, C., Knebel, A. & Trost, M., 20 Sep 2018, In : Cell Chemical Biology. 25, 9, p. 1117-1127.4 11 p.

Research output: Contribution to journalArticle

Open Access
File
Ubiquitin-Protein Ligases
Drug Discovery
Ubiquitin
Ionization
Assays
12 Citations (Scopus)

Inhibition of USP10 induces degradation of oncogenic FLT3

Weisberg, E. L., Schauer, N. J., Yang, J., Lamberto, I., Doherty, L., Bhatt, S., Nonami, A., Meng, C., Letai, A., Wright, R., Tiv, H., Gokhale, P. C., Ritorto, M. S., De Cesare, V., Trost, M., Christodoulou, A., Christie, A., Weinstock, D. M., Adamia, S., Stone, R. & 8 others, Chauhan, D., Anderson, K. C., Seo, H-S., Dhe-Paganon, S., Sattler, M., Gray, N. S., Griffin, J. D. & Buhrlage, S. J., 2 Oct 2017, In : Nature Chemical Biology. 13, p. 1207-1215 9 p.

Research output: Contribution to journalArticle

Acute Myeloid Leukemia
Phosphotransferases
Proteasome Endopeptidase Complex
Ubiquitin
Point Mutation
9 Citations (Scopus)
182 Downloads (Pure)

Lithocholic Acid Hydroxyamide Destabilizes Cyclin D1 and Induces G0/G1 Arrest by Inhibiting Deubiquitinase USP2a

Magiera, K., Tomala, M., Kubica, K., De Cesare, V., Trost, M., Zieba, B. J., Kachamakova-Trojanowska, N., Les, M., Dubin, G., Holak, T. A. & Skalniak, L., 20 Apr 2017, In : Cell Chemical Biology. 24, 4, p. 458-470 13 p., e18.

Research output: Contribution to journalArticle

Open Access
File
Lithocholic Acid
Cyclin D1
Derivatives
Cell Cycle
Cells