Borodkin, Vladimir

Dr

  • 885 Citations
  • 16 h-Index
20012019
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Fingerprint Dive into the research topics where Vladimir Borodkin is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 10 Similar Profiles
Uridine Diphosphate Medicine & Life Sciences
Glycosylation Medicine & Life Sciences
Proteins Medicine & Life Sciences
Threonine Medicine & Life Sciences
Peptides Medicine & Life Sciences
Catalytic Domain Medicine & Life Sciences
Serine Medicine & Life Sciences
Substrates Chemical Compounds

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Research Output 2001 2019

42 Downloads (Pure)

Catalytic deficiency of O-GlcNAc transferase leads to X-linked intellectual disability

Pravata, V., Muha, V., Gundogdu, M., Ferenbach, A., Kakade, P., Vandadi, V., Wilmes, A. C., Borodkin, V., Joss, S., Stavridis, M. & van Aalten, D., 23 Jul 2019, In : Proceedings of the National Academy of Sciences. 116, 30, p. 14961-14970 10 p.

Research output: Contribution to journalArticle

Open Access
File
Intellectual Disability
Host Factor 1 Protein
Missense Mutation
Proteome
Catalytic Domain

Genetic recoding to dissect the roles of site-specific protein O-GlcNAcylation

Gorelik, A., Galan Bartual, S., Borodkin, V., Varghese, J., Ferenbach, A. & van Aalten, D., 6 Nov 2019, In : Nature Structural & Molecular Biology. 26, p. 1071-1077 7 p.

Research output: Contribution to journalArticle

Clustered Regularly Interspaced Short Palindromic Repeats
Proteins
Proteome
Dissection
hexosaminidase C
1 Citation (Scopus)
68 Downloads (Pure)

O-GlcNAcase Fragment Discovery with Fluorescence Polarimetry

Borodkin, V. S., Rafie, K., Selvan, N., Aristotelous, T., Navratilova, I., Ferenbach, A. T. & Van Aalten, D. M. F., 18 May 2018, In : ACS Chemical Biology. 13, 5, p. 1353-1360 8 p.

Research output: Contribution to journalArticle

Open Access
File
Polarimeters
Fluorescence
Assays
Hexosaminidase B
Cardiovascular Diseases
68 Downloads (Pure)

The conserved threonine-rich region of the HCF-1PRO repeat activates promiscuous OGT: UDP-GlcNAc glycosylation and proteolysis activities

Kapuria, V., Röhrig, U. F., Waridel, P., Lammers, F., Borodkin, V. S., van Aalten, D. M. F., Zoete, V. & Herr, W., 16 Nov 2018, In : Journal of Biological Chemistry. 293, 46, p. 17754-17768 15 p.

Research output: Contribution to journalArticle

Open Access
File
Proteolysis
Glycosylation
Host Factor 1 Protein
Uridine Diphosphate
Threonine
3 Citations (Scopus)
50 Downloads (Pure)

Thio-linked UDP-peptide conjugates as O-GlcNAc transferase inhibitors

Rafie, K., Gorelik, A., Trapannone, R., Borodkin, V. & Van Aalten, D., 20 Jun 2018, In : Bioconjugate Chemistry. 29, 6, p. 1834-1840 7 p.

Research output: Contribution to journalArticle

Open Access
File
Uridine Diphosphate
Peptides
Polarimeters
Fluorophores
Cell-Penetrating Peptides