• 19 Citations
  • 2 h-Index
20172019
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Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 18 Similar Profiles
Lysophosphatidic Acid Receptors Medicine & Life Sciences
Central Nervous System Agents Medicine & Life Sciences
Proteolysis Chemical Compounds
Enzyme kinetics Chemical Compounds
Drug Discovery Medicine & Life Sciences
Scaffolds Chemical Compounds
Central Nervous System Medicine & Life Sciences
Lead Engineering & Materials Science

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Research Output 2017 2019

  • 19 Citations
  • 2 h-Index
  • 4 Article
1 Citation (Scopus)
36 Downloads (Pure)

SPR-measured dissociation kinetics of PROTAC ternary complexes influence target degradation rate

Roy, M., Winkler, S., Hughes, S. J., Whitworth, C., Galant, M., Farnaby, W., Rumpel, K. & Ciulli, A., 15 Mar 2019, In : ACS Chemical Biology. 14, 3, p. 361-368 8 p.

Research output: Contribution to journalArticle

Open Access
File
Proteolysis
Enzyme kinetics
Degradation
Ubiquitin-Protein Ligases
Assays
1 Citation (Scopus)

Identification of compounds acting as negative allosteric modulators of the LPA receptor

Ellery, J., Dickson, L., Cheung, T., Ciuclan, L., Bunyard, P., Mack, S., Buffham, W. J., Farnaby, W., Mitchell, P., Brown, D., Isaacs, R. & Barnes, M., 15 Aug 2018, In : European Journal of Pharmacology. 833, p. 8-15 8 p.

Research output: Contribution to journalArticle

Lysophosphatidic Acid Receptors
Interferometry
Physiological Phenomena
Arrestin
Benzoic Acid
12 Citations (Scopus)

Assessing molecular scaffolds for CNS drug discovery

Mayol-Llinas, J., Nelson, A., Farnaby, W. & Ayscough, A., Jul 2017, In : Drug Discovery Today. 22, 7, p. 965-969 5 p.

Research output: Contribution to journalArticle

Central Nervous System Agents
Drug Discovery
Central Nervous System
Blood-Brain Barrier
Pharmaceutical Preparations
5 Citations (Scopus)
41 Downloads (Pure)

Modular synthesis of thirty lead-like scaffolds suitable for CNS drug discovery

Mayol-Llinàs, J., Farnaby, W. & Nelson, A., 3 Nov 2017, In : Chemical Communications. 53, 91, p. 12345-12348 4 p.

Research output: Contribution to journalArticle

Open Access
File
Scaffolds
Lead
Drug Discovery