Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Dive into the research topics where William Farnaby is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Projects
- 2 Not started
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KinoGlu: A Chemical Strategy to Illuminate CNS Biology
Engineering and Physical Sciences Research Council
1/07/23 → 30/06/26
Project: Research
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Breaking free from the crystal lattice: Structural biology in solution to study protein degraders
Haubrich, K., Spiteri, V., Farnaby, W., Sobott, F. & Ciulli, A., Apr 2023, In: Current Opinion in Structural Biology. 79, 9 p., 102534.Research output: Contribution to journal › Review article › peer-review
Open AccessFile6 Downloads (Pure) -
Crystallization of VHL-based PROTAC-induced ternary complexes
Wijaya, A. J., Farnaby, W. & Ciulli, A., 2023, Targeted Protein Degradation. Burslem, G. L. (ed.). Academic Press Inc., Vol. 681. p. 241-263 23 p. (Methods in Enzymology).Research output: Chapter in Book/Report/Conference proceeding › Chapter
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Discovery of soticlestat, a potent and selective inhibitor for cholesterol 24-hydroxylase (CH24H)
Koike, T., Yoshikawa, M., Ando, H. K., Farnaby, W., Nishi, T., Watanabe, E., Yano, J., Miyamoto, M., Kondo, S., Ishii, T. & Kuroita, T., 26 Aug 2021, In: Journal of Medicinal Chemistry. 64, 16, p. 12228-12244 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile14 Citations (Scopus)13 Downloads (Pure) -
Transforming targeted cancer therapy with PROTACs: A forward-looking perspective
Farnaby, W., Koegl, M., McConnell, D. B. & Ciulli, A., Apr 2021, In: Current Opinion in Pharmacology. 57, p. 175-183 9 p.Research output: Contribution to journal › Review article › peer-review
Open AccessFile22 Citations (Scopus)82 Downloads (Pure) -
PROTEOLYSIS TARGETING CHIMERA (PROTACS) AS DEGRADERS OF SMARCA2 AND/OR SMARCA4
Ciulli, A., Dank, C., Diers, E., Farnaby, W., Roy, M., Steurer, S. & Trainor, N., 23 Apr 2020, Patent No. WO/2020/078933, 14 Oct 2019, Priority date 16 Oct 2018, Priority No. 18200596.7Research output: Patent
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Drug Discovery Today: Technologies (Journal)
Alessio Ciulli (Guest editor) & William Farnaby (Guest editor)
2018 → 2019Activity: Publication peer-review and editorial work types › Editorial activity
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Chemical Probes Portal (www.chemicalprobes.org) (External organisation)
William Farnaby (Chair)
1 Oct 0202 → …Activity: Membership types › Membership of panel