Projects per year
Personal profile
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Dive into the research topics where William Farnaby is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Unlocking Mitophagy Activation With Small Molecule Targeted Protein Stabilisers - Fellowship (Joint with UCL/Francis Crick Institute)
Farnaby, W. (Investigator)
1/10/23 → 30/09/28
Project: Research
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KinoGlu: A Chemical Strategy to Illuminate CNS Biology
Farnaby, W. (Investigator)
1/07/23 → 31/10/26
Project: Research
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Novel Bifunctional Chemistries For Unbiased Exploration Of Targeted Protein Degradation Mechanisms
Ciulli, A. (Investigator) & Farnaby, W. (Investigator)
Project: Research
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Early Career - Target Protein Degradation Network (Joint with University of Glasgow and University of Strathclyde)
Ciulli, A. (Investigator), Eugui Anta, A. (Investigator), Farnaby, W. (Investigator), Haubrich, K. (Investigator), Mojsa, B. (Investigator) & Spiteri, V. (Investigator)
Project: Research
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Discovery of a CNS active GSK3 degrader using orthogonally reactive linker screening
Holmqvist, A., Kocaturk, N. M., Duncan, C., Riley, J., Baginski, S., Marsh, G., Cresser-Brown, J., Maple, H., Juvonen, K., Sathe, G., Morrice, N., Sutherland, C., Read, K. D. & Farnaby, W. (Lead / Corresponding author), 6 Oct 2025, In: Nature Communications. 16, 16 p., 8857.Research output: Contribution to journal › Article › peer-review
Open AccessFile16 Link opens in a new tab Citations (Scopus)122 Downloads (Pure) -
Frustration in the protein-protein interface plays a central role in the cooperativity of PROTAC ternary complexes
Ma, N., Bhattacharya, S., Muk, S., Jandova, Z., Schmalhorst, P. S., Ghosh, S., Le, K., Diers, E., Trainor, N., Farnaby, W., Roy, M. J., Kofink, C., Greb, P., Weinstabl, H., Ciulli, A., Bader, G., Sankar, K., Bergner, A. (Lead / Corresponding author) & Vaidehi, N., Dec 2025, In: Nature Communications. 16, 1, 8595.Research output: Contribution to journal › Article › peer-review
Open AccessFile12 Link opens in a new tab Citations (Scopus)73 Downloads (Pure) -
Identification of a Highly Cooperative PROTAC Degrader Targeting GTP-loaded KRAS(on) Alleles
Vetma, V., Puoti, I., Karolak, N. K., Chakraborti, S., Diers, E., Girardi, E., Khan, S., Kidd, G., Kropatsch, K. G., Mclennan, R., O'Connor, S., Samwer, M., Trainor, N., Whitworth, C., Wijaya, A. J., Wong, J. Y. F., Zollman, D., Farnaby, W., Popow, J. & Ciulli, A. (Lead / Corresponding author) & 2 others, , 12 Nov 2025, In: Journal of the American Chemical Society. 147, 45, p. 41367-41378 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile6 Link opens in a new tab Citations (Scopus)106 Downloads (Pure) -
Stick it with VHL
Farnaby, W. (Lead / Corresponding author), Nov 2025, In: Nature Chemical Biology. 21, 11, p. 1644-1645 2 p.Research output: Contribution to journal › Comment/debate › peer-review
Open AccessFile57 Downloads (Pure) -
Confounding Factors in Targeted Degradation of Short-Lived Proteins
Vetma, V., Perez, L. C., Eliaš, J., Stingu, A., Kombara, A., Gmaschitz, T., Braun, N., Ciftci, T., Dahmann, G., Diers, E., Gerstberger, T., Greb, P., Kidd, G., Kofink, C., Puoti, I., Spiteri, V., Trainor, N., Weinstabl, H., Westermaier, Y. & Whitworth, C. & 6 others, , 19 Jul 2024, In: ACS Chemical Biology. 19, 7, p. 1484-1494 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile34 Link opens in a new tab Citations (Scopus)192 Downloads (Pure)
Datasets
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Crystal Structure of compound 4 in complex with KRAS G12V C118S GDP and pVHL:ElonginC:ElonginB
Zollman, D. (Creator), Farnaby, W. (Creator) & Ciulli, A. (Creator), Research Collaboratory for Structural Bioinformatics Protein Data Bank, 6 Dec 2023
DOI: 10.2210/pdb8qw7/pdb
Dataset
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KRAS-G12C in Complex with Compound 1
Popow, J. (Creator), Farnaby, W. (Creator), Gollner, A. (Creator), Kofink, C. (Creator), Fischer, G. (Creator), Wurm, M. (Creator), Zollman, D. (Creator), Wijaya, A. (Creator), Mischerikow, N. (Creator), Hasenoehrl, C. (Creator), Prokofeva, P. (Creator), Arnhof, H. (Creator), Arce-Solano, S. (Creator), Bell, S. (Creator), Boeck, G. (Creator), Diers, E. (Creator), Frost, A. (Creator), Goodwin-Tindall, J. (Creator), Karolyi-Oezguer, J. (Creator), Khan, S. (Creator), Klawatsch, T. (Creator), Koegl, M. (Creator), Kousek, R. (Creator), Kratochvil, B. (Creator), Kropatsch, K. (Creator), Lauber, A. A. (Creator), McLennan, R. (Creator), Olt, S. (Creator), Peter, D. (Creator), Petermann, O. (Creator), Roessler, V. (Creator), Stolt-Bergner, P. (Creator), Strack, P. (Creator), Strauss, E. (Creator), Trainor, N. (Creator), Vetma, V. (Creator), Whitworth, C. (Creator), Zhong, S. (Creator), Quant, J. (Creator), Weinstabl, H. (Creator), Kuster, B. (Creator), Ettmayer, P. (Creator) & Ciulli, A. (Creator), Research Collaboratory for Structural Bioinformatics Protein Data Bank, 6 Dec 2023
DOI: 10.2210/pdb8QUG/pdb
Dataset
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Crystal Structure of compound 3 in complex with KRAS G12V C118S GDP and pVHL:ElonginC:ElonginB
Zollman, D. (Creator), Farnaby, W. (Creator) & Ciulli, A. (Creator), Research Collaboratory for Structural Bioinformatics Protein Data Bank, 6 Dec 2023
DOI: 10.2210/pdb8qw6/pdb
Dataset
Activities
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Scientists from CeTPD visit Greyfriars Primary School, St. Andrews
Farnaby, W. (Presenter), Mortlock, H. (Presenter), Mcintosh, W. (Presenter) & Kidd, G. (Advisor)
9 Jun 2026 → 11 Jun 2026Activity: Other activity types › Schools engagement
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Dundee Research Interest Group Open Doors Day 2026
Alessi, D. (Speaker), Howden, A. (Organiser), Hawdon, B. (Organiser), Bandmann, O. (Speaker), Hardie, G. (Contributor), Caldwell, M. (Speaker), Rigg, D. (Contributor), Donaldson, K. (Contributor), Donaldson, M. (Contributor), Robertson, B. (Contributor), Robertson, H. (Contributor), Sammler, E. (Speaker), Cellan-Jones, R. (Speaker), Milne, J. (Contributor), Flitton, C. (Presenter), Elshani, S. (Presenter), Lis, P. (Presenter), Gomes Moreira, S. (Presenter), Farnaby, W. (Presenter), Kidd, G. (Presenter), Goodburn, J. (Organiser), Hallatt, A. (Presenter), Robertson, J. (Presenter), Urbina Teixidor, A. (Presenter), Tan, Z. Y. (Presenter), Ganley, I. (Presenter), Kiely, M. (Contributor), Muqit, M. (Presenter), de Marcos Lousa, C. (Presenter), Yang, Z. (Presenter), Zeneviciute, K. (Presenter), Langlands, A. (Presenter), Edwards, A. (Contributor), McNeill , C. (Contributor), Clarke, R. (Presenter), Lefter, N. (Presenter), Baker, C. (Presenter), Patrick, S. (Contributor), Hirons, Z. (Advisor), Nash, L. (Contributor), Macmillan, C. (Contributor), Jacobs, L. (Contributor), Munro, D. (Contributor), Nelson, H. (Contributor), Taylor, L. (Contributor), Ellmers, M. (Contributor), Matson, S. (Contributor), Sahu, M. (Presenter), Pratuseviciute, N. (Presenter), Promchai, N. (Presenter) & Fasimoye, R. (Presenter)
27 Jan 2026Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Dundee Research Interest Group Open Doors Day 2025
Alessi, D. (Participant), Sammler, E. (Organiser), Howden, A. (Organiser), Muqit, M. (Participant), Ganley, I. (Participant), Gilbertson, T. (Participant), Farnaby, W. (Participant), Hardie, G. (Participant), Hawdon, B. (Organiser), Goodburn, J. (Organiser), Coxe, M. (Participant), Milne, J. (Participant), Rigg, D. (Participant), Vangheluwe, P. (Participant), Kerr, J. (Participant), Stewart, T. (Participant), Lacey-Solymar, G. (Participant), Patrick, S. (Participant), Nash, L. (Participant), Langlands, A. (Participant), Hirons, Z. (Organiser), Grayson, L. (Contributor), Bishnu, A. (Participant), Wilhelm, L. (Participant), Appleton, P. (Participant), Filipe Soares, R. (Participant), Robertson, J. (Participant), Ibba, R. (Participant), Hallatt, A. (Participant) & Wieske, L. (Participant)
28 Feb 2025Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar
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Alzheimer's Scotland and patient parents' visit to School of Life Sciences
Green, C. (Organiser), Ahmed, M. (Participant), Ashford, M. (Participant), Ciulli, A. (Participant), Farnaby, W. (Participant), Cossar, P. (Participant) & Kidd, G. (Participant)
25 Nov 2025Activity: Other activity types › Other
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Nuffield Research Placement Hosting
Farnaby, W. (Member)
24 Jun 2024 → 5 Jul 2024Activity: Other activity types › Public engagement and outreach - public lecture/debate/seminar