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Nicholson, William

Dr

 https://orcid.org/0000-0001-6614-0194
  • 625 Citations
  • 9 h-Index
1993 …2019
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Research Output 1993 2019

  • 625 Citations
  • 9 h-Index
  • 22 Article
  • 3 Conference contribution
  • 1 Poster
  • 1 Meeting abstract
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Article
2019
3 Citations (Scopus)

A domestication history of dynamic adaptation and genomic deterioration in Sorghum

Smith, O., Nicholson, W., Kistler, L., Mace, E., Clapham, A., Rose, P., Stevens, C., Ware, R., Samavedam, S., Barker, G., Jordan, D., Fuller, D. Q. & Allaby, R. G., 8 Apr 2019, In : Nature Plants. 5, 4, p. 369-379 11 p.

Research output: Contribution to journal › Article

domestication
Sorghum (Poaceae)
deterioration
introgression
genomics
1 Citation (Scopus)

EMSY expression affects multiple components of the skin barrier with relevance to atopic dermatitis

Elias, M. S., Wright, S. C., Remenyi, J., Abbott, J. C., Bray, S. E., Cole, C., Edwards, S., Gierlinski, M., Glok, M., McGrath, J. A., Nicholson, W. V., Paternoster, L., Prescott, A. R., Have, S. T., Whitfield, P. D., Lamond, A. I. & Brown, S. J., Aug 2019, In : Journal of Allergy and Clinical Immunology. 144, 2, p. 470-481 12 p.

Research output: Contribution to journal › Article

Open Access
Atopic Dermatitis
Skin
Genome-Wide Association Study
Keratinocytes
Skin Diseases
16 Downloads (Pure)

Proteomic analysis of a filaggrin-deficient skin organoid model shows evidence of increased transcriptional-translational activity, keratinocyte-immune crosstalk and disordered axon guidance

Elias, M. S., Wright, S. C., Nicholson, W. V., Morrison, K. D., Prescott, A. R., Ten Have, S., Whitfield, P. D., Lamond, A. I. & Brown, S. J., 30 Sep 2019, In : Wellcome Open Research. 4, p. 1-21 21 p., 134.

Research output: Contribution to journal › Article

Open Access
File
Organoids
Crosstalk
Keratinocytes
Proteomics
Skin
2016
24 Citations (Scopus)
23 Downloads (Pure)

The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2

Liang, C-C., Li, Z., Lopez-Martinez, D., Nicholson, W. V., Vénien-Bryan, C. & Cohn, M. A., 13 Jul 2016, In : Nature Communications. 7, p. 1-10 10 p., 12124 .

Research output: Contribution to journal › Article

Open Access
File
anemias
Fanconi Anemia
Towers
towers
deoxyribonucleic acid
2013

Erratum: Growth of large and highly ordered 2D crystals of a KD channel, structural role of lipidic environment (Biophysical Journal (2013) 105: 2 (398-408))

De Zorzi, R., Nicholson, W. V., Guigner, J-M., Erne-Brand, F. & Vénien-Bryan, C., 2013, In : Biophysical Journal. 105, 5, p. 1285 1 p.

Research output: Contribution to journal › Article

Manuscripts
Switzerland
Growth
3 Citations (Scopus)

Growth of large and highly ordered 2D crystals of a K+ channel, structural role of lipidic environment

De Zorzi, R., Nicholson, W. V., Guigner, J-M., Erne-Brand, F. & Vénien-Bryan, C., 16 Jul 2013, In : Biophysical Journal. 105, 2, p. 398-408 11 p.

Research output: Contribution to journal › Article

Crystallography
Crystallization
Inwardly Rectifying Potassium Channel
Growth
Membrane Proteins
2012

Comparison of the Structure of a Bacterial Potassium Channel in Both 2D and 3D Crystals

Zorzi, R. D., Nicholson, W. V., Tucker, S. J. & Vénien-Bryan, C., 31 Jan 2012, In : Biophysical Journal. 102, 3, p. 536a 1 p.

Research output: Contribution to journal › Article

Channelopathies
Inwardly Rectifying Potassium Channel
Bacterial Structures
Crystallography
Water-Electrolyte Balance
36 Citations (Scopus)

Structure and operation of the DNA-translocating type I DNA restriction enzymes

Kennaway, C. K., Taylor, J. E., Song, C. F., Potrzebowski, W., Nicholson, W., White, J. H., Swiderska, A., Obarska-Kosinska, A., Callow, P., Cooper, L. P., Roberts, G. A., Artero, J-B., Bujnicki, J. M., Trinick, J., Kneale, G. G. & Dryden, D. T. F., 2012, In : Genes and Development. 26, p. 92-104 13 p.

Research output: Contribution to journal › Article

Type I Site Specific Deoxyribonucleases
DNA
Type II Site Specific Deoxyribonucleases
Enzymes
DNA Restriction-Modification Enzymes
2010
3 Citations (Scopus)

An approach to automated acquisition of cryoEM images from lacey carbon grids

Nicholson, W. V., White, H. & Trinick, J., 3 Sep 2010, In : Journal of Structural Biology. 172, 3, p. 395-399 5 p.

Research output: Contribution to journal › Article

Myosin Type V
Carbon
Automation
Actins
Nitrogen
2004
4 Citations (Scopus)

Correlation-based methods of automatic particle detection in electron microscopy images with smoothing by anisotropic diffusion

Nicholson, W. V. & Malladi, R., 2004, In : Journal of Microscopy. 213, 2, p. 119-128 10 p.

Research output: Contribution to journal › Article

Electron Microscopy
Noise
Theoretical Models
4 Citations (Scopus)

Object detection by correlation coefficients using azimuthally averaged reference projections

Nicholson, W. V., 18 Oct 2004, In : IEEE Transactions on Biomedical Engineering. 51, 11, p. 2006-2012 7 p.

Research output: Contribution to journal › Article

Electrons
Additive noise
Macromolecules
Electron microscopes
Object detection
2002
306 Citations (Scopus)

Microtubule structure at 8 Å resolution

Li, H., DeRosier, D. J., Nicholson, W. V., Nogales, E. & Downing, K. H., 2002, In : Structure. 10, 10, p. 1317-1328 12 p.

Research output: Contribution to journal › Article

Tubulin
Microtubules
Cryoelectron Microscopy
Crystallography
Zinc
2001
82 Citations (Scopus)

Review: Automatic particle detection in electron microscopy

Nicholson, W. V. & Glaeser, R. M., 2001, In : Journal of Structural Biology. 133, 2-3, p. 90-101 12 p.

Research output: Contribution to journal › Article

Particle Size
Electron Microscopy
Technology
1999
25 Citations (Scopus)

Cryo-electron microscopy of GDP-tubulin rings

Nicholson, W. V., Lee, M., Downing, K. H. & Nogales, E., Jun 1999, In : Cell Biochem Biophys. 31, 2, p. 175-183 9 p.

Research output: Contribution to journal › Article

Guanosine
Diphosphates
Tubulin
Electron microscopy
Polymers
1997
6 Citations (Scopus)

Rebinding of the extrinsic proteins of Photosystem II studied by electron microscopy and single particle alignment: an assessment with small two-dimensional ordered arrays of Photosystem II

Rosenberg, M. F., Holzenburg, A., Shepherd, F. H., Nicholson, W. V., Flint, T. D. & Ford, R. C., 28 Mar 1997, In : Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1319, 1, p. 119-132 14 p.

Research output: Contribution to journal › Article

Photosystem II Protein Complex
Electron microscopy
Electron Microscopy
Photosynthetic membranes
Membrane Proteins
1996
12 Citations (Scopus)

A current assessment of photosystem II structure

Nicholson, W. V., Ford, R. C. & Holzenburg, A., Apr 1996, In : Bioscience Reports. 16, 2, p. 159-187 29 p.

Research output: Contribution to journal › Article

Photosystem II Protein Complex
Thylakoids
Electron microscopy
Electron Microscopy
Electrons
21 Citations (Scopus)

Direct Methods in Protein Electron Crystallography: the Ab Initio Structure Determination of Two Membrane Protein Structures in Projection using Maximum Entropy and Likelihood

Gilmore, C. J., Nicholson, W. V. & Dorset, D. L., 1 Nov 1996, In : Acta Crystallographica Section A: Foundations and Advances. 52, 6, p. 937-946 10 p.

Research output: Contribution to journal › Article

Halorhodopsins
Porins
Crystallography
Macromolecules
Escherichia coli

Phasing the cholera toxin electron-diffraction data using the maximum entropy likelihood method with non-crystallographic symmetry imposed in the MICE computer program

Nicholson, W. N. & Gilmore, C. J., 8 Aug 1996, In : Acta Crystallographica Section A: Foundations and Advances. 52, Suppl., p. C68 1 p.

Research output: Contribution to journal › Article

cholera
electron diffraction
projection
entropy
computer programs

The ab initio solution of the halorhodopsin and Omp F porin membrane proteins at 6 Å from electron diffraction projection data using the maximum entropy likelihood method in the MICE computer program

Gilmore, C. J., Nicholson, W. N. & Dorset, D. L., 8 Aug 1996, In : Acta Crystallographica Section A: Foundations and Advances. 52, Suppl., p. C65 1 p.

Research output: Contribution to journal › Article

Halorhodopsins
Porins
Entropy
Membrane Proteins
Software
1993

4-Methoxyindan-1-one oxime

Nicholson, W. V., Sawyer, L., Taylor, P., Dawson, I. & Gould, R. O., Jan 1993, In : Acta Crystallogr Sect C Cryst Struct Commun. 3 p.

Research output: Contribution to journal › Article

82 Citations (Scopus)

Three-dimensional structure of photosystem II

Holzenburg, A., Bewley, M. C., Wilson, F. H., Nicholson, W. V. & Ford, R. C., 3 Jun 1993, In : Nature. 363, p. 470-472 3 p.

Research output: Contribution to journal › Article

photosystem II
multiprotein complexes
proteins
digital images
thylakoids
13 Citations (Scopus)

Thromboxane receptor active analogues based on the 6-oxabicyclo[3.2.1]octane ring system

Muir, G., Jones, R. L., Will, S. G., Winwick, T., Peesapati, V., Wilson, N. H., Griffiths, N., Nicholson, W. V., Taylor, P., Sawyer, L. & Blake, A. J., 1993, In : European Journal of Medicinal Chemistry. p. 609-624 15 p.

Research output: Contribution to journal › Article