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Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

  • 2 Similar Profiles
Ubiquitin-Protein Ligases Medicine & Life Sciences
Anions Chemical Compounds
Cations Chemical Compounds
Histones Chemical Compounds
Ions Chemical Compounds
Proteins Engineering & Materials Science
Molecules Chemical Compounds
Pyrroles Chemical Compounds

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Research Output 2009 2018

  • 478 Citations
  • 13 h-Index
  • 23 Article
  • 2 Review article
  • 1 Meeting abstract
  • 1 Editorial
1 Citations

3-Fluoro-4-hydroxyprolines: Synthesis, conformational analysis and stereoselective recognition by the VHL E3 ubiquitin ligase for targeted protein degradation

Testa, A., Lucas, X., Castro, G., Chan, K. H., Wright, J., Runcie, A., Gadd, M., Harrison, W. T. A., Ko, E. J., Fletcher, D. & Ciulli, A., 25 Jul 2018, In : Journal of the American Chemical Society. 140, 29, p. 9299-9313 15 p.

Research output: Contribution to journalArticle

Open Access
File
Hydroxyproline
Ubiquitin-Protein Ligases
Proteolysis
Proteins
Degradation
Ubiquitin-Protein Ligases
Proteins
Homeostasis
X-Rays
Ligands
1 Citations

Targeting ligandable pockets on PHD zinc finger domains by a fragment-based approach

Amato, A., Lucas, X., Bortoluzzi, A., Wright, D. & Ciulli, A., 20 Apr 2018, In : ACS Chemical Biology. 13, 4, p. 915-921 7 p.

Research output: Contribution to journalArticle

Open Access
File
Zinc Fingers
Histones
Zinc
Homeodomain Proteins
Plant Structures
1 Citations

Thioamide substitution to probe the hydroxyproline recognition of VHL ligands

Soares, P., Lucas, X. & Ciulli, A., 23 Mar 2018, In : Bioorganic & Medicinal Chemistry. 4 p.

Research output: Contribution to journalArticle

Open Access
Thioamides
Hydroxyproline
Substitution reactions
Ligands
Hydrogen
4 Citations

Beyond the BET family: targeting CBP/p300 with 4-acyl pyrroles

Hügle, M., Lucas, X., Ostrovskyi, D., Regenass, P., Gerhardt, S., Einsle, O., Hau, M., Jung, M., Breit, B., Günther, S. & Wohlwend, D., 27 Sep 2017, In : Angewandte Chemie International Edition. 56, 41, p. 12476-12480 6 p.

Research output: Contribution to journalArticle

Open Access
File
Pyrroles
Cells
Cell proliferation
Screening
Crystal structure