Kulathu, Yogesh

Dr

  • United Kingdom

20082026
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Personal profile

Keywords

  • Q Science (General)
  • Signal transduction
  • Cancer Biology
  • Immunology
  • structural Biology
  • post-translational modifications
  • Biochemistry
  • ubiquitin

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

Ubiquitin Medicine & Life Sciences
Polyubiquitin Medicine & Life Sciences
Ubiquitination Medicine & Life Sciences
B-Cell Antigen Receptors Medicine & Life Sciences
Ubiquitin-Protein Ligases Medicine & Life Sciences
Tumors Chemical Compounds
B-Lymphocytes Medicine & Life Sciences
Immunoreceptor Tyrosine-Based Activation Motif Medicine & Life Sciences

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Projects 2013 2026

Research Output 2008 2019

27 Downloads (Pure)

Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling

Kelsall, I. R., Kristariyanto, Y. A., Knebel, A., Wood, N. T., Kulathu, Y. & Alpi, A. F., 22 Feb 2019, In : Journal of Biological Chemistry. 294, 8, p. 2651-2664 14 p.

Research output: Contribution to journalArticle

Open Access
File
Cullin Proteins
Ubiquitin-Protein Ligases
Ligases
Ubiquitin
Ubiquitins
17 Citations (Scopus)
47 Downloads (Pure)

Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability

Kwasna, D., Rehman, S. A. A., Natarajan, J., Matthews, S., Madden, R., De Cesare, V., Weidlich, S., Virdee, S., Ahel, I., Gibbs-Seymour, I. & Kulathu, Y., 5 Apr 2018, In : Molecular Cell. 70, 1, p. 150-164.e6 15 p.

Research output: Contribution to journalArticle

Open Access
File
Genomic Instability
Ubiquitin
Polyubiquitin
DNA Damage
Catalysis
2 Citations (Scopus)
40 Downloads (Pure)

Expansion of DUB functionality by alternative isoforms: USP35, a case study

Leznicki, P., Natarajan, J., Bader, G., Spevak, W., Schlattl, A., Rehman, S. A. A., Pathak, D., Weidlich, S., Zoephel, A., Bordone, M. C., Barbosa-Morais, N. L., Boehmelt, G. & Kulathu, Y., 16 May 2018, In : Journal of Cell Science. 131, 16 p., jcs212753 .

Research output: Contribution to journalArticle

Open Access
File
Protein Isoforms
Ubiquitination
TNF-Related Apoptosis-Inducing Ligand
Endoplasmic Reticulum Stress
Staurosporine
Immunoreceptor Tyrosine-Based Activation Motif
Synthetic Biology
B-Cell Antigen Receptors
Amplification
Tyrosine
9 Citations (Scopus)
46 Downloads (Pure)

A single MIU motif of MINDY-1 recognizes K48-linked polyubiquitin chains

Kristariyanto, Y., Rehman, S. A. A., Weidlich, S., Knebel, A. & Kulathu, Y., 1 Mar 2017, In : EMBO Reports. 18, 3, p. 392-402 11 p., e201643205.

Research output: Contribution to journalArticle

Open Access
File
Polyubiquitin
Ubiquitin
Tandem Repeat Sequences
Binders
Conformations

Thesis

Quantitative Deubiquitinase (DUB) Interactomics to Dissect the Biology of Cancer Associated DUBs

Author: Natarajan, J., 2019

Supervisor: Kulathu, Y. (Supervisor)

Student thesis: Doctoral ThesisDoctor of Philosophy