Kapelyukh, Yury

Dr

  • 25 Citations
  • 2 h-Index
20142019
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Fingerprint Dive into the research topics where Yury Kapelyukh is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 6 Similar Profiles
Pharmaceutical Preparations Medicine & Life Sciences
Cytochrome P-450 Enzyme System Medicine & Life Sciences
Cytochrome P-450 CYP1A2 Medicine & Life Sciences
Cytochrome P-450 CYP1A1 Medicine & Life Sciences
Cytochromes b5 Medicine & Life Sciences
Drug Interactions Medicine & Life Sciences
Liver Medicine & Life Sciences
Knockout Mice Medicine & Life Sciences

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Research Output 2014 2019

  • 25 Citations
  • 2 h-Index
  • 5 Article
  • 1 Chapter
27 Downloads (Pure)

An Extensively Humanized Mouse Model to Predict Pathways of Drug Disposition and Drug/Drug Interactions, and to Facilitate Design of Clinical Trials

Henderson, C. J., Kapelyukh, Y., Scheer, N., Rode, A., McLaren, A., MacLeod, K., Lin, D., Wright, J., Stanley, L. A. & Wolf, C. R., Jun 2019, In : Drug Metabolism and Disposition. 47, 6, p. 601-615 15 p.

Research output: Contribution to journalArticle

Open Access
File
Drug Interactions
Clinical Trials
Pharmaceutical Preparations
Pharmacokinetics
Cytochrome P-450 CYP3A
Open Access
Cytochrome P-450 CYP1A2
Cytochrome P-450 CYP1A1
Knockout Mice
Pharmaceutical Preparations
Enzyme Inhibitors

Application of Humanised and Other Transgenic Models to Predict Human Responses to Drugs

Wolf, C. R., Kapelyukh, Y., Scheer, N. & Henderson, C. J., 20 Nov 2016, New Horizons in Predictive drug Metabolism and Pharmocokentics. 49 ed. Royal Society of Chemistry, Vol. 2016-January. p. 152-176 25 p. (RSC Drug Discovery Series; vol. 2016-January, no. 49).

Research output: Chapter in Book/Report/Conference proceedingChapter

Genetically Modified Animals
Drug and Narcotic Control
Pharmaceutical Preparations
Animal Models
Genes
13 Citations (Scopus)

Defining human pathways of drug metabolism in vivo through the development of a multiple humanized mouse model

Scheer, N., Kapelyukh, Y., Rode, A., Oswald, S., Busch, D., McLaughlin, L. A., Lin, D., Henderson, C. J. & Wolf, C. R., Nov 2015, In : Drug Metabolism and Disposition. 43, 11, p. 1679-1690 12 p.

Research output: Contribution to journalArticle

Pharmaceutical Preparations
Cytochrome P-450 Enzyme System
Polypharmacy
Oxygenases
Androgen Receptors
Compartment Model
Transgenic Mice
cytochrome
Null
Mouse