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A Centre of Excellence for Lead Optimisation for Diseases of the Developing World (Joint funding by Wellcome & Gates)
Gilbert, Ian
(Investigator)
Gray, David
(Investigator)
Read, Kevin
(Investigator)
Wyatt, Paul
(Investigator)
Biological Chemistry and Drug Discovery
Drug Discovery Unit
Overview
Research Outputs
(2)
Project Details
Status
Finished
Effective start/end date
1/07/13
→
31/10/18
Funding
Wellcome Trust
(100195/Z/12/Z (VIA MILESTONE)):
£3,572,417.00
View all
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Research Output
Research Output per year
2018
2018
2
Article
Research Output per year
Research Output per year
A role for trypanosomatid aldo-keto reductases in methylglyoxal, prostaglandin and isoprostane metabolism
Roberts, A., Dunne, J., Scullion, S.,
Norval, S.
&
Fairlamb, A.
,
29 Aug 2018
,
In:
Biochemical Journal.
475
,
16
,
p. 2593-2610
18 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
benzonidazole
Aldo-Keto Reductases
Isoprostanes
Parasites
Pyruvaldehyde
2
Citations (Scopus)
141
Downloads (Pure)
Pharmacokinetics of β-Lactam Antibiotics: Clues from the Past to Help Discover Long-Acting Oral Drugs in the Future
Smith, P. W.,
Zuccotto, F.
, Bates, R. H., Martinez-Martinez, M. S.,
Read, K. D.
,
Peet, C.
&
Epemolu, O.
,
12 Oct 2018
,
In:
ACS Infectious Diseases.
4
,
10
,
p. 1439-1447
9 p.
Research output
:
Contribution to journal
›
Article
›
peer-review
Open Access
File
Lactams
Pharmacokinetics
Anti-Bacterial Agents
Pharmaceutical Preparations
Drug Discovery
9
Citations (Scopus)
170
Downloads (Pure)