Research output per year
Research output per year
Project Details
| Status | Finished |
|---|---|
| Effective start/end date | 1/07/13 → 31/10/18 |
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
Datasets
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BindingDB Entry 50015035: Optimization of TAM16, a Benzofuran That Inhibits the Thioesterase Activity of Pks13; Evaluation toward a Preclinical Candidate for a Novel Antituberculosis Clinical Target.
BindingDB, Green, S. (Creator), Wyatt, P. (Creator), Wilson, C. (Creator), Ray, P. (Creator), Zuccotto, F. (Creator), Hernandez, J. (Creator), Aggarwal, A. (Creator), Mackenzie, C. (Creator), Caldwell, N. (Creator), Taylor, M. (Creator), Huggett, M. (Creator), Mathieson, M. (Creator), Murugesan, D. (Creator), Smith, A. (Creator), Davis, S. (Creator), Cocco, M. (Creator), Parai, M. K. (Creator), Acharya, A. (Creator), Tamaki, F. (Creator), Scullion, P. (Creator), Epemolu, O. (Creator), Riley, J. (Creator), Stojanovski, L. (Creator), Lopez-Román, E. M. (Creator), Torres-Gómez, P. A. (Creator), Toledo, A. M. (Creator), Guijarro-Lopez, L. (Creator), Camino, I. (Creator), Engelhart, C. A. (Creator), Schnappinger, D. (Creator), Massoudi, L. M. (Creator), Lenaerts, A. J. (Creator), Robertson, G. T. (Creator), Matthews, D. (Creator), Floyd, D. (Creator), Sacchettini, J. C. (Creator), Read, K. (Creator), Encinas, L. (Creator) & Bates, R. H. (Creator), BindingDB, 15 Dec 2023
DOI: 10.7270/q24t6p88
Dataset
Research output
- 8 Article
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Design and development of lysyl tRNA synthetase inhibitors, for the treatment of tuberculosis
Davis, S. H., Mathieson, M., Buchanan, K. I., Dawson, A., Smith, A., Cocco, M., Tamaki, F. K., Post, J. M., Baragaña, B., Jansen, C., Kiczun, M., Zuccotto, F., Wood, G., Scullion, P., Ray, P. C., Epemolu, O., Lopez-Román, E. M., Guijarro López, L., Engelhart, C. A. & Kim, J. & 8 others, , 14 Aug 2025, In: Journal of Medicinal Chemistry. 68, 15, p. 16459-16482 24 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)103 Downloads (Pure) -
Identification of a series containing a pentafluorophenyl moiety that targets Pks13 to inhibit growth of Mycobacterium tuberculosis
Green, S. (Lead / Corresponding author), Harrison, J., Thompson, S., Murugesan, D., Libardo, M. D. J., Engelhart, C. A., Meshanni, J., Fletcher, D. A., Scullion, P., Edwards, D., Epemolu, O., Mutter, N., Shishikura, Y., Riley, J., Ioerger, T. R., Roca Guillén, J. J., Guijarro-Lopez, L., Read, K. D., Barry, C. E. & Schnappinger, D. & 3 others, , 14 Mar 2025, In: ACS Infectious Diseases. 11, 3, p. 715-726 12 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Link opens in a new tab Citations (Scopus)113 Downloads (Pure) -
Identification and Optimization of Novel Inhibitors of the Polyketide Synthase 13 Thioesterase Domain with Antitubercular Activity
Green, S. R. (Lead / Corresponding author), Wilson, C., Eadsforth, T. C., Punekar, A. S., Tamaki, F. K., Wood, G., Caldwell, N., Forte, B., Norcross, N. R., Kiczun, M., Post, J. M., Lopez-Román, E. M., Engelhart, C. A., Lukac, I., Zuccotto, F., Epemolu, O., Boshoff, H. I. M., Schnappinger, D., Walpole, C. & Gilbert, I. H. & 3 others, , 23 Nov 2023, In: Journal of Medicinal Chemistry. 66, 22, p. 15380-15408 29 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile19 Link opens in a new tab Citations (Scopus)366 Downloads (Pure)